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CABOZANTINIB TABLET (CABOMETYX)

Mfd. by :- Exelixis (Fulfilled By : Magicine Pharma)

Cabozantinib Tablet (Cabometyx)

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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Overview of Cabozantinib 20mg Tablet

Cabometyx (Cabozantinib) is used to treat certain types of cancer (kidney, thyroid, liver). This medication works by slowing or stopping the growth of cancer cells. The recommended dose of medicine is decided by your medical advisor. This medicine comes in the form of tablets and is to be taken on an empty stomach. It is advisable not to change or stop the dose without taking permission from your doctor. Some side effects may occur during your treatment with this medicine. Do not crush, chew, or break the tablet. 

Pharmacodynamics of Cabometyx (Cabozantinib 20mg Tablet) 

Cabozantinib suppresses metastasis, angiogenesis, and oncogenesis by inhibiting receptor tyrosine kinases. After oral administration, the effect of this medicine can be observed in 2-5 hours. 

Side effect of  Cabometyx (Cabozantinib 20mg Tablet) 

This medicine may cause some serious and unwanted side effects. Which requires immediate medical attention otherwise it can also lead to higher risk. Do not forget to discuss the risk and benefits of this medication with your doctor. 

Common side effects 

  • Blurred vision 

  • Severe headache 

  • Dizziness 

  • Nausea 

  • Coughing up blood 

  • Diarrhea 

  • Hair loss 

  • Change in taste

  • Joint pain 

  • Weight loss

  • Loss of appetite 

  • Bleeding 

  • Irregular heartbeat 

  • Fainting 

  • Anxiety 

  • Pounding in ears 

  • Shortness of breath 

  • Blood clots 

  • Loss of coordination 

  • Dry mouth 

  • Muscle spasms 

  • Dehydration 

  • Fainting 

  • Anemia 

  • Swelling 

  • Wounds that don’t heal 

  • Jaw pain 

  • Hypertension 

  • Numbness 

  • Heartburn 

  • Sunken eyes 

Note- if a side effect occurs, immediately contact your doctor. 

Dosage

Take this medicine as prescribed by your doctor. Do not crush or chew. Take this medicine on an empty stomach. Take this medicine one hour before or two hours after the meals. 

Missed dose 

  •  It is advisable not to miss a dose. If you miss a scheduled dose of this medicine, contact your doctor immediately. 

Overdose 

  • In case of an overdose, the doctor will provide emergency medical treatment.

Usage of Cabometyx (Cabozantinib) 

Cabometyx is used to treat metastatic kidney or thyroid cancer. This medication works by blocking signals that allow cancer cells to grow and multiply. This medicine also helps to block the growth of new blood vessels in the area of the tumor. Take this medicine on an empty stomach. Take this medicine one hour before or two hours after the meals. Your doctor will set your dosing schedule according to your medical conditions and response to the treatment. 

Do not stop the use of this medicine without taking permission from your doctor. Take this medicine as prescribed by your medical advisor. Try not to miss your regular dosing schedule. Protect this medicine from heat and light.

Warnings

Before starting treatment with the Cabometyx tablet, do not forget to discuss your previous medical history with your doctor. 

  •  Contraception 

    • Use effective methods of contraception to prevent pregnancy while taking this medicine. 

  • Children and adolescents 

    • This medicine is not advisable for use in children and adolescents. 

 

Warnings for female 

  • Pregnancy 

    • Cabometyx tablets shouldn’t be used by women who are pregnant. It is recommended that this medication should be avoided during pregnancy. 

 

  • Breastfeeding 

    • This medicine is not recommended in breastfeeding unless it is necessary. Please consult your medical advisor before starting treatment with this medication. 

General warning and precautions

  • This medication delays wound healing. 

  • Do not take this medicine with food. 

  • Avoid the use of grapefruit products while taking this medicine. 

  • Do not breastfeed while taking this medicine. 

  • This drug may cause dizziness. 

  • Before starting treatment tell the doctor about your previous medical history. 

  • Do not receive any vaccinations before consulting with your doctor.

Cautions

  • Do not crush, chew, or break the tablet. 

  • Do not drive or operate heavy machinery. 

  • Not safe for pregnant women. 

  • Do not breastfeed while receiving this medication.

Q1. What is Cabometyx (Cabozantinib 20mg Tablet)?

Ans. Cabometyx is used to treat metastatic kidney or thyroid cancer. This medicine also helps to block the growth of new blood vessels in the area of the tumor. 

Q2. How does Cabometyx (Cabozantinib 20mg Tablet) work? 

Ans. Cabometyx (Cabozantinib) is used to treat certain types of cancer (kidney, thyroid, liver). This medication works by blocking signals that allow cancer cells to grow and multiply.

Q3. In what strength is it available? 

Ans. It is available in the strength of 20mg, 40mg, and 60mg. 

Q4. What are the common side effects? 

Ans. Some common side effects are:- Anemia, blurred vision, dizziness, fever, dehydration, loss of appetite, nausea, diarrhea, irregular heartbeat, etc. 

Q5. What should I avoid while receiving this medicine? 

Ans. Avoid the use of grapefruit products while taking this medicine.  

Q6. How to take this medicine? 

Ans. Take this medicine on an empty stomach, at least 1 hour before or 2 hours after the meal.   

Q7. What are the self-care tips? 

Ans. Maintain good nutrition and get plenty of rest.

Q8. How long does it take this medicine to show effect? 

Ans. The effect of this medicine can be observed in 2 to 5 hours.  

Q9. Can I take this medicine during pregnancy?

Ans. This medicine is not recommended for pregnant women. 

Q10. Can I take this medicine during breastfeeding? 

Ans. This medicine is not recommended in breastfeeding unless it is necessary.

Q11. Can I consume alcohol while taking this medicine? 

Ans. It is not known whether it is safe or not. Please consult your doctor before consuming alcohol. 

Q12. What are the storage conditions? 

Ans. Store this medicine at room temperature. 

Q13.  What happens if I miss a dose? 

Ans. If you miss a scheduled dose of this medicine, contact your doctor immediately. 

Q14. Can I drive after taking this medicine? 

Ans. This medicine may decrease your ability to drive or affect your vision. Do not drive if any symptoms occur.

Interactions

Interactions may change how your medication works and increase the risk for side effects. Don’t forget to disclose your previous medical history with the doctor.

Medicine interaction 

  • Adenosine  

  • Avapritinib 

  • Dalteparin 

  • Flutamide 

  • Ibrutinib 

  • Methadone 

  • Ritonavir 

  • Ticlopidine 

  • Warfarin 

Disease interaction 

  • Lung toxicity 

  • Hypertension 

  • Renal impairment 

  • Hepatic impairment 

  • Hemorrhagic events 

Alcohol interaction 

  • Interaction with alcohol is unknown, please consult your doctor before consuming alcohol. 

Contraindications

  • Cabometyx medicine is not recommended for use in patients with a known allergy to Cabozantinib.  

  • This medicine is contracted in patients known to be hypersensitive.

https://www.magicinepharma.com/tablet/cabometyx-cabozantinib

Above Content has been reviewed by Professionals