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ERIBULIN MESYLATE 0.44MG/ML INJECTION (HALAVEN)

Mfd. by :- Eisai Pharmaceuticals (Fulfilled By : Magicine Pharma)

Eribulin Mesylate 0.44mg/ml Injection (Halaven)

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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Medicine Details  

Brand Name: Halaven   

Generic Name: Eribulin mesylate 

Manufacturer: Eisai Pharmaceuticals India Pvt Ltd 

Dosage Form: Injection 

Strength: 1mg/2ml 

Composition: Eribulin mesylate 

Packaging: 1vial 

Indication: Breast cancer  

Storage: Store at room temperature  

Overview 

Halaven (Eribulin mesylate) injection is used for the treatment of metastatic breast cancer (cancer that has spread to other parts of the body). This medicine belongs to a class of medications antineoplastic. It works by interfering with the microtubule structures which helps the cancer cells to divide and multiply.  It is important to take a Halaven injection as prescribed by your doctor. The recommended dose of Epitero injection is decided by a doctor according to your previous medical condition and response to the treatment. This medicine is given as an infusion into your vein. Do not self administer this medicine. 

Pharmacodynamics 

Halaven 1mg/2ml treatment of human breast cancer cells caused changes in morphology and gene expression as well as decreased migration and invasiveness in vitro. It inhibits the growth phase of microtubules without affecting the shortening phase and sequesters tubulin into nonproductive aggregates.  

Usage   

This medicine is used when breast cancer has spread to other parts of the body. Halaven injection helps to stop the growth of cancerous cells and also prevents the multiplication of cancerous cells. Do not take this medicine in the wrong way as it may lead to some severe side effects. If you experience any signs and symptoms while receiving this medicine, inform your doctor immediately. It is advisable not to change or stop the dose without taking suggestions from your doctor. This medicine increases the risk of dizziness. Avoid activities that require more concentration. This injection affects your immune system and may increase the risk of getting infections or bleeding more easily.  

​Interactions 

Halaven injection can interact with other medications and it may increase the risk for side effects. Don’t forget to disclose and discuss your previous medical history with the doctor. 

Medicine Interactions  

  • Moxifloxacin  

  • Adalimumab  

  • Lefamulin  

  • Siponimod  

  • Etanercept  

Disease Interactions  

  • Infections  

  • Renal impairment 

  • Hepatic impairment  

Alcohol Interaction   

  • Interaction with alcohol is unknown. Please consult your doctor while having treatment with this medicine.  

Contraindications 

  • Do not take this medicine if you are allergic to Eribulin mesylate.  

  • Halaven injection is not recommended in patients known to be hypersensitive. 

Side effects  

This medicine may cause some common side effects. Discuss the risks and benefits of the Halaven injection with the doctor before starting the treatment. 

Common side effects  

  • Anemia  

  • Weakness  

  • Hair loss  

  • Constipation  

  • Fatigue  

  • Irregular heartbeat  

  • Dizziness  

  • Decrease white blood cell count  

  • Loss of strength  

  • Fainting  

  • Weight loss  

  • Bloating  

  • Sore throat  

  • Headache  

  • Dry mouth  

  • Runny nose  

  • Muscle stiffness  

  • Back pain  

  • Indigestion  

  • Diarrhea  

  • Rash  

  • Loss of appetite  

  • Tingling and numbness of feet and hand  

  • Cough  

  • Pale skin  

  • Unusual bleeding  

  • Nasal congestion  

  • Decreased urination  

  • Anxiety  

  • Change of taste  

  • Shortness of breath  

  • Inflammation  

  • Dehydration  

  • Fever  

  • Vomiting  

Note -  Contact your medical practitioner if any side effects occur. 

Dosage 

Take this injection as prescribed by your doctor. The injection is given as an infusion into your vein by a doctor or nurse. Do not self administer.  

Missed dose  

  • It is advisable not to miss a dose. If you miss an appointment for a scheduled dose of Halaven injection, contact your doctor immediately.  

Overdose  

  • In case of an overdose of Halaven injection, the doctor will provide emergency medical treatment. 

Warnings  

Before starting treatment with Halaven medicine, please inform your doctor about your previous medical history. If you experience any signs and symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk.  

  •  Contraception  

  • Use suitable methods of contraception to prevent pregnancy while taking this medicine.  

  • Children and adolescents  

  •  Halaven injection is not advisable for use in children and adolescents.  

Warnings for female  

  • Pregnancy 

  • Do not use Halaven medicine if you are planning to become pregnant. Avoid this medication at the time of pregnancy.  

  • Breastfeeding 

  • This medicine is not recommended in breastfeeding unless it is required. Please consult with your doctor before starting treatment with this medication. 

Precautions 

  • This medicine may cause prolongation of the QT interval.  

  • Halaven injection may decrease white blood cells and increase the risk of infections in patients.  

  • Inform your doctor if you experience any side effects like - anemia, infection, nausea, unusual weakness, muscle pain, fever, and bleeding.  

  • Do not skip the scheduled dose of this medicine.  

  • Close monitoring of blood cell counts and electrolyte levels is required during treatment with this medicine.  

  • Avoid contact with people who have infections.  

Cautions 

  • Do not self administer.  

  • Do not drive or operate heavy machinery. 

  • Not safe for pregnant women.  

  • Do not breastfeed while receiving this medication. 

Q1. What is Halaven (Eribulin mesylate)? 

Ans. This injection is used for the treatment of metastatic breast cancer. It helps to stop the growth of cancerous cells and also prevents the multiplication of cancerous cells.  

Q2.  What are the side effects?  

Ans. Some common side effects are - low blood platelets, pale skin, fever, bleeding gums, vomiting, dizziness, etc.  

Q3. How does Halaven injection work?  

Ans. It works by interfering with the microtubule structures which helps the cancer cells to divide and multiply. 

Q4. Can I drive after taking this medicine?  

Ans. This medicine may affect your vision and your ability to concentrate. 

Q5. In what strength is it available?  

Ans. It is available in the strength of 1mg/2ml.  

Q6. Can I take this medicine during pregnancy?  

Ans. This medicine is not recommended during pregnancy.  

Q7. What happens if I miss a dose?  

Ans. If you miss a scheduled dose of Halaven injection, contact your doctor immediately. 

Q8. How to take this injection?  

Ans. It is given as an infusion into the vein. Do not self administer this medicine. 

Q9. Can I consume alcohol while receiving this medicine?  

Ans. Please consult your doctor before consuming alcohol.  

Q10. What should I avoid while receiving this medication?  

Ans. Avoid contact with people who have infections.  

Q11. Can I take this medicine during breastfeeding?  

Ans. This medicine is not recommended in breastfeeding unless it is necessary.  

Q12. Does this medicine affect liver function?  

Ans. Please consult your doctor before consuming this drug. 

Q13. What are the storage conditions?  

Ans. Store this medicine at room temperature.  

Above Content has been reviewed by Professionals