What is Iclusig (Ponatinib)?
Iclusig 15mg is used to treat certain types of blood cancer (chronic myelogenous leukemia-CML, acute lymphoblastic leukemia-ALL).
How does Iclusig (Ponatinib) work?
Ponatinib is designed to block tumor cell growth in various ways. Ponatinib aims several proteins (called tyrosine kinases) on the surface of cancer cells, as well as targets within the cell. Several of these targets are thought to be involved in angiogenesis (making of blood vessels). By blocking these targets, it is expected the cancer will shrink.
How do I take Iclusig (Ponatinib)?
Start dosing with 15 mg or 45mg once daily. Consider reducing the dose of Iclusig for patients with chronic phase (CP) CML and accelerated phase (AP) CML who have achieved a major cytogenetic response.
What does Iclusig consist of?
Iglusig consists of Ponatinib.
What strengths is Iclusig available in?
Iclusig is available in 15mg/45mg.
What precautions do I need to be aware of before taking Iclusig (Ponatinib)?
There are some precautions you should know about before taking Iclusig (Ponatinib).
1) Iclusig is not recommended for pregnant women as it harm the unborn baby. 2) Do not take any type of vaccinations while you are taking Iclusig without consulting your doctor. 3) Do not drink grapefruit juice or eat grapefruit during treatment with Iclusig (Ponatinib).
4) Do not breast feed while taking Iclusig.
What are the side effects of Iclusig (Ponatinib)?
There are some serious side effects of Iclusig (Ponatinib). Some of these are headache, dizziness, constipation, or loss of appetite may occur. Ponatinib sometimes causes side effects due to the rapid destruction of cancer cells (tumor lysis syndrome). To lower your risk, your doctor may add a medication and tell you to drink plenty of fluids. For women of childbearing age, ponatinib may affect your ability to have children.