What is Ledifos (Ledipasvir and Sofosbuvir)?
The fixed-dose combination of ledipasvir-sofosbuvir provides an effective and well-tolerated one-pill once-a-day option for treatment of genotypes 1, 4, 5, and 6 chronic hepatitis C (HCV) infection. This direct-acting antiviral regimen was the first FDA-approved interferon- and ribavirin free regimen to treat hepatitis C.
Ledipasvir-sofosbuvir can be used without ribavirin in most patients with genotype 1A, except those who are cirrhotic and treatment-experienced.
How does Ledifos (Ledipasvir and Sofosbuvir) work?
Sofosbuvir is in a class of antiviral medications called nucleotide polymerase inhibitors. They work by lowering the amount of hepatitis C virus. Ledipasvir is in a class of antiviral medications called HCV NS5A inhibitors. It works by stopping the virus that causes hepatitis C from spreading inside the body.
How do I take Ledifos (Ledipasvir and Sofosbuvir)?
Take Ledifos in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. It may be taken with or without food, but it is better to take it at a fixed time.
What does Ledifos comprise of?
Ledifos comprises of Ledipasvir 90 Mg + Sofosbuvir 400 Mg.
What precautions do I need to be aware of before consuming Ledifos (Ledipasvir and Sofosbuvir)?
There are some precautions you need to take before consuming Ledifos (Ledipasvir and Sofosbuvir).
1) if you are taking antacids containing aluminum hydroxide or magnesium hydroxide (Maalox, Mylanta, Tums, others), take them 4 hours before or 4 hours after taking ledipasvir
2) If you become pregnant while taking ledipasvir and sofosbuvir, call your doctor.
What are the side effects of Ledifos (Ledipasvir and Sofosbuvir)?
There are some serious/deteriorating side effects of Ledifos (Ledipasvir and Sofosbuvir).
Side effects include tiredness, headache, difficulty falling asleep or staying asleep, nausea, diarrhea, cough, dizziness, muscle pain and irritability
Serious side effects include rash, blisters, swelling of the face, arms, or legs and shortness of breath