LYNPARZA

Mfd. by :- AstraZeneca (Fulfilled By : Magicine Pharma)

 Lynparza

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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Brand Name: Lynparza   

Generic Name: Olaparib  

Manufacturer: AstraZeneca  

Dosage Form: Capsule  

Strength: 50mg  

Composition: Olaparib  

Packaging: 112 capsules per bottle  

Indication: Breast cancer and cervical cancer  

Storage: Store at room temperature  

Overview 

Lynparza (Olaparib) medicine is used in the treatment of certain types of cancer (Breast, Fallopian tube, and Ovarian cancer). This medication works by preventing cancer cells from repairing damage to their DNA. This is an anti-cancer medicine that helps to decrease the growth of tumors in both monotherapy and chemotherapy. The recommended dose of medicine is decided by the doctor. Do not take this medicine in the wrong way as it may lead to some severe side effects. It is advisable not to change or stop the dose without taking suggestions from your doctor. If you experience any symptoms while receiving this medicine, inform your doctor immediately. Do not chew or open the capsule.   

Pharmacodynamics of Lynparza  

Lynparza Tablets is an inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes, including PARP1, PARP2, and PARP3. PARP enzymes are involved in normal cellular homeostasis, such as DNA transcription, cell cycle regulation, and DNA repair. After the oral administration, the effect of this medicine can be observed in 1 to 3 hours.  

Usage of Lynparza  

This medicine is used to treat ovarian cancer and pancreatic cancer with certain abnormal inherited genes. It works by slowing the growth of cancerous cells. The dose is decided by a doctor according to your previous medical condition and response to the treatment. Do not miss your regular dosing schedule. Avoid eating grapefruit and Seville orange because this may increase the chance of side effects. This medication may take some time to show results. Do not breastfeed while taking this medicine. Store this medication at room temperature and keep it away from light and moisture. Do not take this medicine if you are allergic to olapari

Side effects of Lynparza  

This medicine may cause some mild or severe side effects. Discuss the risks and benefits of this medication with the doctor before starting the treatment. 

Common side effects   

  • Diarrhea  

  • Nausea  

  • Loss of appetite  

  • Vomiting  

  • Fatigue  

  • Anemia  

  • Taste change  

  • Abdominal pain  

  • Indigestion  

  • Irregular heartbeat  

  • Weight loss  

  • Dizziness  

  • Muscle pain  

  • Cough  

  • Mouth sores  

  • Rash  

  • Bleeding gums  

  • Pale skin  

  • Nasal congestion  

  • Difficulty in breathing  

  • Infections  

  • Severe headache  

  • Fainting  

  • Blurred vision  

  • Heartburn  

  • Low white blood cell counts  

  • Tiredness and weakness  

  • Loss of strength  

  • Joint pain  

  • Difficulty in swallowing  

  • Tingling and painful sensation  

  • Low platelet counts 

  • Back pain  

  • Abnormal kidney function  

  • Runny nose  

  • Respiratory tract infections 

  • Drowsiness  

Note- immediately contact your doctor if any side effects occur  

Dosage 

Take this medicine as prescribed by your doctor. Do not skip or miss your dosing schedule. Take this medicine orally twice a day.  

Missed dose  

  •  It is advisable not to miss a dose. If you miss a scheduled dose of this medicine, contact your doctor immediately.  

Overdose  

  • In case of an overdose, the doctor will provide emergency medical treatment. 

Warnings of  Lynparza

Before starting treatment with the Lynparza capsule, please inform your doctor about your previous medical history. If you experience any symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk.  

  •  Contraception  

  • Use effective methods of contraception to prevent pregnancy while taking this medicine.  

  • Children and adolescents  

  • This medicine is not advisable for use in children and adolescents.  

Warnings for female  

Pregnancy 

  • Do not use a Lynparza capsule if you are pregnant or planning to become pregnant. Avoid this medication at the time of pregnancy.  

Breastfeeding 

  • This medicine is not recommended in breastfeeding unless it is necessary. Please consult your medical advisor before starting treatment with this medication. 

Precautions of  Lynparza

  • Before using this medicine tell your doctor if you have kidney, liver, and breathing problems.  

  • Do not receive any kind of immunizations without consulting your doctor.  

  • The use of this medicine may affect your immune system. 

  • Avoid the use of grapefruit products and Seville orange.  

  • This medicine may increase the risk of bleeding.  

  • Avoid contact with people who have infections.  

  • This medicine may decrease your red blood cells.  

Caution of  Lynparza

  • Do not drive or operate heavy machinery.  

  • Not safe for pregnant women.  

  • Do not breastfeed while receiving this medication.  

  • Do not chew or open the capsule. 

Q1. What is Lynparza (Olaparib)?  

Ans. This medicine is used in the treatment of ovarian cancer. It helps to slow or stop the growth of cancer cells.  

Q2. How does Lynparza (Olaparib) work?  

Ans. This medication works by preventing cancer cells from repairing damage to their DNA.  

Q3. What are the side effects?  

Ans. Some common side effects are:- nausea, fatigue, anemia, diarrhea, dizziness, muscle pain, indigestion, irregular heartbeat, difficulty in breathing, etc.  

Q4. How to take this medicine?  

Ans. Take this medicine as prescribed by your doctor. Do not chew or open the capsule.  

Q5. What should I avoid while receiving this medicine?  

Ans. Avoid drinking or eating grapefruit products and Seville orange. 

Q6.  In what strength is it available?  

Ans. It is available in the strength of 50mg.  

Q7.  What happens if I miss a dose?  

Ans. If you miss a scheduled dose of this medicine, contact your doctor immediately. 

Q8. Can I take this medicine during pregnancy? 

Ans. This medicine is not recommended for pregnant women. 

Q9. Can I consume alcohol while taking this medicine?  

Ans. It is not known whether it is safe or not. Please consult your doctor before consuming alcohol.  

Q10. Can I drive after taking this medicine?  

Ans. This medicine may affect your vision. Do not drive if any symptoms occur.  

Q11.  Can I take this medicine during breastfeeding?  

Ans. This medicine is not recommended in breastfeeding unless it is necessary. 

Q12. What are self-care tips?  

Ans. Keep yourself hydrated and get plenty of rest.  

Q13.  Does this medicine affect kidney function?  

Ans. Please contact your doctor before consuming this drug. 

Q14. What are the storage conditions?  

Ans. Store this medicine at room temperature and protect it from light and moisture.

Interaction of  Lynparza

Interactions may change how your medication works and increase the risk for side effects. Don’t forget to disclose your previous medical history with the doctor.  

Medicine Interactions  

  • Ciprofloxacin  

  • Imatinib  

  • Ozanimod  

  • Deferiprone  

  • Erythromycin  

  • Letermovir  

  • Mitotane  

Disease interactions 

  • Hepatic impairment  

  • Renal impairment  

  • Hematologic toxicities  

  • Pulmonary abnormality  

Alcohol interaction  

  • Interaction with alcohol is unknown. Please consult your doctor before consuming alcohol.  

Contraindications 

  • Do not use this medicine if you are allergic to olaparib.  

  • This medicine is not recommended in patients known to be hypersensitive. 

Above Content has been reviewed by Professionals