Mfd. by :- Pfizer (Fulfilled By : Magicine Pharma)
Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.
Brand Name:- Doxorubicin
Generic Name:- Doxorubicin Hydrochloride
Manufacturer:- Pfizer
Dosage Form:- Injection
Strength:- 200mg/100ml
Composition:- Doxorubicin Hydrochloride
Packaging:- 1vial
Indication:- Ovarian cancer, Kaposi’s sarcoma, and multiple myeloma
Storage:- Store this medicine in the refrigerator.
Doxorubicin is used to treat certain types of cancer (ovarian cancer, AIDs related to Kaposi’s sarcoma, and multiple myeloma). This medication belongs to the group of antineoplastics (cancer-fighting medications) known as anthracyclines. Doxorubicin medicine works by slowing or stopping the growth of cancer cells. Take this medicine as prescribed by your medical advisor. Dosage is based on your medical condition and your response to the treatment. This medicine is given as an infusion into your vein. Do not self administer this medicine. Do not take this medicine in the wrong way as it may lead to some severe side effects. If you experience any symptoms while receiving this medicine, inform your doctor immediately.
Doxorubicin is an antineoplastic in the anthracycline class. Doxorubicin forms complexes with DNA by intercalation between base pairs, and it inhibits topoisomerase II activity by stabilizing the DNA-topoisomerase II complex, preventing the relegation portion of the ligation-relegation reaction that topoisomerase II catalyzes.
It is an anti-cancer medication that is used for the treatment of blood, ovaries, and Kaposi’s sarcoma (a type of cancer that causes lesions to grow below the surface of the skin, lymph nodes, etc.) It can lower blood cells that help your body to fight infections. This medicine must be given slowly as an infusion into the vein. It is important to take this medicine exactly as prescribed by your medical advisor. Do not skip or miss the dosing schedule. It is advisable not to change or stop the dose without taking suggestions from your doctor. Do not use this medicine if you are pregnant.
This medicine may cause some major and minor side effects. Discuss the risks and benefits of this medication with the doctor before starting the treatment.
Common side effects
Severe headache
Rash
Sore throat
Nausea
Fever
Vomiting
Pain at the injection site
Dizziness
Muscle pain
Diarrhea
Hair loss
Cough
Loss of appetite
Constipation
Blisters
Anxiety
Shortness of breath
Tiredness
Abdominal pain
Chest pain
Shortness of breath
Irregular heartbeat
Back pain
Difficulty in urination
Pale skin
Fever with chills
Dehydration
Mouth ulcers
Painful blisters on hand and feet
Low blood pressure
Pin when eating and swallowing
Red spots on the skin
Drowsiness
Low red and white blood cells
Blurred vision
Red and itchy eyes
Note- immediately contact your doctor if any side effects occur.
Take this injection as prescribed by your doctor. The injection is given as an infusion into your vein by a doctor or nurse. Do not self administer.
It is advisable not to miss a dose. If you miss an appointment for a scheduled dose of this medicine, contact your doctor immediately.
In case of an overdose, the doctor will provide emergency medical treatment.
Before starting treatment with Doxorubicin, please inform your doctor about your previous medical history. If you experience any symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk.
Contraception
Use effective methods of contraception to prevent pregnancy while taking this medicine.
Children and adolescents
This medicine is not advisable for use in children and adolescents.
Pregnancy
Do not use Doxorubicin if you are pregnant or planning to become pregnant. Avoid this medication at the time of pregnancy.
Breastfeeding
This medicine is not recommended in breastfeeding unless it is necessary. Please consult your medical advisor before starting treatment with this medication.
This medicine may increase the risk of heart failure.
Close monitoring of blood cell count and body temperature is necessary while receiving this medication.
The use of this medicine may decrease the white blood cell count in patients.
Do not receive any vaccines while having treatment with this medicine.
Avoid contact with people who have infections.
Close monitoring of symptoms like mouth ulcers and bleeding is required.
Not safe for pregnant women.
Do not drive or operate heavy machinery.
Do not self administer this medicine.
Do not breastfeed while receiving this medication.
Do not start the treatment if the blood cell count is low
Ans. Doxorubicin is an anti-cancer drug that belongs to a class of medication like anthracyclines. This medication works by slowing or stopping the growth of cancer cells.
Ans. Doxorubicin works by blocking the effect of an enzyme called topoisomerase II that helps cancer cells to divide and grow.
Ans. Some common side effects are:- severe headache, nausea, sore throat, vomiting, dehydration, anxiety, chest pain, rash, irregular heartbeat, shortness of breath, etc.
Ans. It is available in the strength of 200mg/100ml.
Ans. Avoid contact with people who have infections and follow your doctor’s instructions about any restriction.
Ans. If you miss a scheduled dose of this medicine, contact your doctor immediately.
Ans. Keep yourself hydrated and maintain good nutrition.
Ans. It is given as an infusion into the vein. Do not self administer this medicine.
Ans. Please consult your doctor before consuming alcohol.
Ans. This medicine is not recommended for pregnant women.
Ans. This medicine may affect your vision. Do not drive if any symptoms occur.
Ans. Please consult your doctor before consuming this drug.
Ans. This medicine is not recommended during breastfeeding unless it is necessary.
Ans. Store this medicine in the refrigerator.
Interactions may change how your medication works and increase the risk for side effects. Don’t forget to disclose your previous medical history with the doctor.
Methadone
Diltiazem
Pimozide
Tofacitinib
Dexamethasone
Amiodarone
Congestive heart failure
Infections
Hepatic dysfunction
Myelosuppression
Interaction with alcohol is unknown. Please consult your doctor before consuming alcohol.
Use of this medicine is not recommended for patients with a known allergy to Doxorubicin hydrochloride injection.
This medicine is not recommended in patients known to be hypersensitive.