EFAMAT

Mfd. by :- Mylan (Fulfilled By : Magicine Pharma)

Efamat

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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Brand Name: Efamat 

Generic Name: Efavirenz 

Manufacturer: Mylan 

Dosage Form: Tablet 

Strength: 600mg

Composition: Efavirenz 

Indication: HIV

Packaging: 30 tablets 

Storage: Store at room temperature 

Overview 

Efamat (Efavirenz) tablet is a combination of antiretrovirals medications. It is used in the treatment of HIV (Human immunodeficiency virus) infection. This medication helps to reduce the amount of HIV in your body and improves the quality of life. It is important to take Efamat tablets as prescribed by your doctor. It is advisable not to change your regular dosing schedule without taking suggestions from your doctor. The recommended dose of Efamat medicine is decided by a doctor according to your previous medical condition and response to the treatment. 

Pharmacodynamics

Efavirenz belongs to the NNRTI (non-nucleoside reverse transcriptase inhibitors) class of antiretrovirals. Both nucleoside and non-nucleoside RTIs inhibit the same target, the reverse transcriptase enzyme, an essential viral enzyme that transcribes viral RNA into DNA. Unlike nucleoside RTIs, which bind at the enzyme's active site, NNRTIs act allosterically by binding to a distinct site away from the active site known as the NNRTI pocket. Efavirenz is not effective against HIV-2, as the pocket of the HIV-2 reverse transcriptase has a different structure, which confers intrinsic resistance to the NNRTI class.

Usage of medicine

Efamat tablet is an antiviral medicine that is used to treat HIV (Human immunodeficiency virus) infection. This medication prevents them from multiplying and reducing the amount of virus from the body and it helps to boost the immune system to fight against infection. Do not take this medicine in the wrong way. If you experience any signs and symptoms while receiving this medicine, inform your doctor immediately. Close monitoring of liver function tests is required during the treatment with this medicine. 

Interactions 

Efamat tablets can interact with other medications and it may increase the risk for side effects. Don’t forget to disclose and discuss your previous medical history with the doctor.

Medicine Interactions 

  • Cabozantinib

  • Dasatinib 

  • Guanfacine

  • Ciprofloxacin 

  • Bosutinib

  • Amiodarone 

  • Fluconazole 

Disease interactions 

  • Cholesterol 

  • Liver disease

  • Seizures 

Alcohol interaction 

  • Interaction with alcohol is unknown. Please consult your doctor before consuming alcohol. 

Contraindications

  • Do not take this medicine if you are allergic to Efavirenz.

  • Efamat (Efavirenz) medicine is not recommended in patients known to be hypersensitive.

  • This medication is not recommended in patients with severe liver disease.

Alternate brands

  • Effahope 600mg Tablet

  • Efavir 600 Tablet

  • Evirenz 600mg Tablet

  • Efferven 600mg Tablet

  • Revenz 600mg Tablet

Side effects

This medicine may cause some major and minor side effects. Discuss the risks and benefits of the Efamat tablets with the doctor before starting the treatment.

Common side effects 

  • Abdominal pain 

  • Dizziness

  • Skin rash 

  • Headache

  • Vomiting

  • Abnormal dreams 

  • Weight gain 

  • Cough 

  • Delusions 

  • Itching 

  • Fatigue 

  • Anxiety 

  • Fever 

  • Drowsiness

  • Difficulty in sleeping 

  • Increased liver enzymes 

  • Poor concentration 

  • Increased sweating 

  • Swelling 

  • Chest pain 

  • Seizures 

  • Mouth ulcers

  • Itching 

  • Deficiency of granulocytes in the blood

  • Sleepiness 

  • Back pain 

  • Difficult or painful urination 

  • Confusion 

Note - immediately contact your health care provider if any side effects occur.

 

Dosage

Take this medicine as prescribed by your doctor. Do not stop or skip your regular dosing schedule. 

Missed dose 

  • It is advisable not to miss a dose. If you miss a scheduled dose of Efamat tablets, contact your doctor immediately. 

Overdose 

  • In case of an overdose of Efamat tablets, the doctor will provide emergency medical treatment.

Warning 

Before starting treatment with Efamat medicine, please inform your doctor about your previous medical history. If you experience any signs and symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk. 

  •  Contraception 

    • Use suitable methods of contraception to prevent pregnancy while taking Efamat medicine. 

  • Children and adolescents 

    • Efamat Tablets are not recommended for use in children under the age of 3 months or weighing less than 3.5 kg.  

Warnings for female 

  • Pregnancy

    • Do not use Efamat medicine if you are planning to become pregnant. Avoid this medication at the time of pregnancy. 

  • Breastfeeding

    • This medicine is not recommended in breastfeeding unless it is required. Please consult with your doctor before starting treatment with Efamat (Efavirenz).

Precautions

  • Close monitoring of body fat distribution and body weight is required during treatment with this medicine.

  • This medication should be used with caution in some patients because it may increase the risk of CNS side effects like drowsiness, hallucinations, etc. 

  • Efamat tablets may increase the risk of immune reconstitution syndrome.

  • Inform your doctor if you experience any side effects like - headache, insomnia, allergic reaction, fever, anxiety, etc. 

  • Close monitoring of liver function is required. 

Cautions 

  • Do not drive or operate heavy machinery.

  • Do not crush or break the tablet. 

  • Not safe for pregnant women. 

  • Do not breastfeed while receiving this medication.

Q1- What is Efamat?

A- Efamat (Efavirenz) is an antiretroviral medication. It is used in the treatment of HIV (human immunodeficiency virus), the virus that can cause AIDS (acquired immunodeficiency syndrome).

Q2- What are the storage conditions for Efamat (Efavirenz)?

A- Store Efamat at room temperature (10-30°C). Keep it away from children and pets. 

Q3- What are the common side effects of Efamat (Efavirenz)?

A- Some of the side effects of Efamat (Efavirenz) are headache, dizziness, insomnia, sleepiness, allergy, skin rash, itching, agranulocytosis, anxiety. There can be other side effects also. Make sure to consult your healthcare provider if side effects occur.

Q4- What is the composition and strength of Efamat (Efavirenz)?

A-  Efamat comprises Efavirenz. It is available in the strength of 600 mg.

Q5- What are self-care tips?

A- Take help from a healthcare provider to plan a proper diet chart and follow it.

Q6- How should I take Efamat (Efavirenz)?

A- Take Efamat tablet exactly in the same strength as prescribed by the healthcare professional.

Q7- What should be done in case of missed dose?

A- It is advised to take the missed dose of Efamat tablet as soon as you remember. However, do not double up the dose to catch up.

Q8- What are the warnings and precautionary steps?

A- Administer with caution in case of:

1. Liver disease

2. Kidney disease

3 Heart disease

4. Pregnancy

5. Breastfeeding

Q9- Is it safe to take Efamat (Efavirenz) during pregnancy or breastfeeding?

A- It is advised to consult the healthcare professional before consuming the Efamat tablet, during pregnancy or breastfeeding, because it may harm the developing baby.

Q10- Is it safe to drive after taking Efamat (Efavirenz)?

A- Avoid driving or operating heavy machinery if you feel unwell after consuming this medicine.

 

Above Content has been reviewed by Professionals