HEPBEST

Mfd. by :- Mylan (Fulfilled By : Magicine Pharma)

Hepbest

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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PACKAGE

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Brand name - Hepbest

Generic name - Tenofovir Alafenamide 

Manufacturer - Mylan Pharmaceuticals Pvt Ltd

Strength - 25mg

Dosage - Tablet (Oral administration)

Packaging - Bottle

Indication - HIV infection and Hepatitis B Virus infection

Prescription required - Yes

Storage - Store at room temperature (10-30°C)

Description

Hepbest tablet, comprising Tenofovir Alafenamide, is an antiviral medicine. It is prescribed for the treatment of HIV (Human Immunodeficiency Virus) infection and chronic Hepatitis B Virus (HBV) infection. It works to slow or stop the multiplication of the virus in the body and helps to clear the infection. It is advisable to take this medicine exactly as prescribed by the healthcare provider for better efficacy without increasing or decreasing the dose strength. This medicine is available at the best price in India.

Pharmacodynamics 

Tenofovir Alafenamide is an antiviral drug. It is a phosphonamidate prodrug of tenofovir (2’-deoxyadenosine monophosphate analog). It enters primary hepatocytes by passive diffusion and by the hepatic uptake transporters OATP1B1 and OATP1B3. It is converted to Tenofovir through hydrolysis primarily by carboxylesterase 1 (CES1) in primary hepatocytes. Tenofovir is phosphorylated by cellular kinases to the pharmacologically active metabolite Tenofovir Diphosphate. Tenofovir Diphosphate works to inhibit HBV replication through incorporation into viral DNA by the HBV reverse transcriptase, which results in DNA chain-termination.

Usage of Medicine 

Hepbest (Tenofovir Alafenamide) tablet is available in the strength of 25 mg in the form of tablets for oral administration. It is a prescription medicine that helps to slow down the multiplication of the virus in the body. However, this medicine is not a permanent cure for HIV. it is advisable to not skip a dose, or change the dose strength. Swallow the tablet as a whole with water, without breaking, cutting, or chewing it.

Interactions

Medicine interactions should be discussed with the healthcare provider before taking the Hepbest (Tenofovir Alafenamide) tablet. 

Interaction with Medicine

  • Adefovir 

  • Amikacin/Gentamicin

  • Orlistat 

Interaction with Alcohol

Interaction with alcohol is unknown. Make sure to consult your healthcare provider before its consumption.

Contraindications

  • Hepbest (Tenofovir Alafenamide) tablet is not indicated to patients having a known allergy to Tenofovir Alafenamide or any of the inactive ingredients.

  • Hepbest (Tenofovir Alafenamide) tablet is not indicated to patients who are known to be hypersensitive.

Alternate Brands

  • Qvir Kit 

  • Viread 

  • Tenarica 

  • Tenfoclear 

  • Ricovir

  • Hepdoze 

  • Tenvir 

  • Valten

 

Following are the side effects of Hepbest (Tenofovir Alafenamide) tablet. Note that there can be other side effects also. Therefore, it is advisable to consult a medical practitioner if side effects occur or last longer than usual.

  • Headache

  • Fever

  • Diarrhea

  • Vomiting

  • Nausea

  • Skin rash

  • Itching

  • Chills

  • Dizziness 

  • Cough

  • Abdominal pain

Normal Dose

Take this medicine exactly as prescribed by the healthcare provider for better efficacy without increasing or decreasing the dose strength. Swallow the tablet as a whole with water, without breaking, cutting, or chewing it.

Missed Dose

It is advisable to not skip a dose. If you miss a dose, make sure to take it as soon as you remember. However, if it is already the time for your next scheduled dose, skip the missed dose and take the scheduled dose. Also, make sure to not increase the dose strength to catch up with the missed dose.

Overdose

It is advisable to not overdose. In case of overdose, make sure to consult your healthcare provider immediately.

 

Pregnancy or Breastfeeding

It is advisable to consult the healthcare provider before the consumption of Hepbest (Tenofovir Alafenamide) tablet during pregnancy or breastfeeding because this medicine may harm the baby.

Driving 

After the consumption of Hepbest (Tenofovir Alafenamide) tablet, it is advisable to avoid driving or operating heavy machinery if side effects (like blurred vision, lack of concentration) occur.

Liver or Kidney Disease

It is advisable to administer Hepbest (Tenofovir Alafenamide) tablet with utmost caution in the patients having a known liver or/and kidney disease.

Medical History

Make sure to consult your healthcare provider regarding your medical history, medicines you already take (including supplements), and your current medical condition before consuming Hepbest (Tenofovir Alafenamide) tablet.

 

Q1- What is Hepbest (Tenofovir Alafenamide) tablet used for?
A- Hepbest (Tenofovir Alafenamide) tablet is a prescription medicine. It is used in the treatment of HIV (Human Immunodeficiency Virus) infection and chronic Hepatitis B Virus (HBV) infection.

Q2- What is the strength of this medicine?

A- Hepbest (Tenofovir Alafenamide) tablet is available in the strength of 25mg.

Q3- How should I take Hepbest (Tenofovir Alafenamide) tablet?

A- Take this medicine exactly as prescribed by the healthcare provider for better efficacy without increasing or decreasing the dose strength. Swallow the tablet as a whole with water, without breaking, cutting, or chewing it.

Q4- What are the side effects of Hepbest (Tenofovir Alafenamide) tablets?

A- The side effects of Hepbest (Tenofovir Alafenamide) tablets are headache, fever, diarrhea, vomiting, nausea, skin rash, itching, etc. There can be other side effects also. Make sure to consult your healthcare provider if side effects occur or last longer than usual.

Q5- What should I avoid while consuming this medicine?

A- Avoid the consumption of alcohol.

Q6- Can I take Hepbest (Tenofovir Alafenamide) tablet during pregnancy?

A- It is advisable to consult the healthcare provider before the consumption of Hepbest (Tenofovir Alafenamide) tablet during pregnancy because this medicine may harm the developing baby.

Q7- Can I take Hepbest (Tenofovir Alafenamide) tablet during breastfeeding? 

A- It is advisable to consult the healthcare provider before the consumption of Hepbest (Tenofovir Alafenamide) tablet during breastfeeding because this medicine may harm the baby.

Q8- Can I take this medicine in liver/kidney disease?

A- It is advisable to administer Hepbest (Tenofovir Alafenamide) tablet with utmost caution in the patients having a known liver or/and kidney disease.

Q9- Can I drive after consuming Hepbest (Tenofovir Alafenamide) tablet?

A- After the consumption of Hepbest (Tenofovir Alafenamide) tablet, it is advisable to avoid driving or operating heavy machinery if side effects (like blurred vision, lack of concentration) occur.

Q10- Is it a habit-forming medicine?

A- No, it is not a habit-forming medicine.

 

Above Content has been reviewed by Professionals