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pfizer ltd
30 tablets
Nirmatrelvir And Ritonavir
Keep in cold place
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Overview
Paxlovid is an antiviral therapy that has two separate medication formulations which are packed together. The first medication is nirmatrelvir, which inhibits a key enzyme that the COVID virus requires in order to make functional virus particles. The second medication is ritonavir, which shuts down nirmatrelvir’s metabolism in the liver, so that it doesn’t move out of your body as quickly, allowing it to work longer. Together, these two medications are highly effective in fighting the COVID infection.
HIV
Nirmatrelvir is a great way to inhibit the SARS-CoV-2 main protease (Mpro). Mpro is responsible for processing polyprotein precursors, and by inhibiting it, we can prevent viral replication. Ritonavir is a fantastic pharmacokinetic enhancer that helps increase nirmatrelvir plasma concentrations. Not to mention, it has no activity against SARS-CoV-2 Mpro. Together, these two drugs make a great team against the virus!
Following are the possible side effects that can occur during your treatment with Paxlovid tablet (Nirmatrelvir and Ritonavir). Contact your medical practitioner immediately if any of the above-mentioned side effects appear.
Diarrhea
Muscle aches
Nausea
Abdominal pain
Throat tightness
Skin rash
Hoarseness
Hives
Increased blood pressure
Trouble swallowing and breathing
Paxlovid is a two-drug oral antiviral regimen consisting of nirmatrelvir and ritonavir, indicated for the treatment of COVID-19 in adults who do not require supplemental oxygen and who are at an increased risk of progression to severe disease.3

Alcohol
unsafe
Do not consume alcohol while taking Paxlovid tablet (Nirmatrelvir and Ritonavir)

Pregnancy
consult your doctor
Do not take Paxlovid tablet (Nirmatrelvir and Ritonavir) without consulting the doctor, in case of pregnancy.

Breast Feeding
consult your doctor
Do not take Paxlovid tablet (Nirmatrelvir and Ritonavir) if you're breastfeeding. Consultation of the doctor is advised.

Driving
danger
It is advisable not to drive or operate heavy machinery, you may feel dizzy as one of the side effects of Paxlovid tablet (Nirmatrelvir and Ritonavir).

Kidney
precaution
Do not take Paxlovid tablet (Nirmatrelvir and Ritonavir) without a doctor's consultation in case of kidney problems.

Liver
precaution
Share your medical history with the doctor in case of liver disease before taking Paxlovid tablet (Nirmatrelvir and Ritonavir).
It is advisable not to miss a dose. If you miss a scheduled dose of Paxlovid tablet (Nirmatrelvir and Ritonavir), contact your doctor immediately.
Individuals suffering from severe liver disease cannot take Paxlovid tablets.
Paxlovid tablets showed improved signs of COVID-19 and improved symptoms within a day or two.
Paxlovid can sometimes show signs of changes in taste, high blood pressure, and abdominal pain in certain patients.
Patients should isolate for a maximum of 5 days after taking paxlovid tablets.
Yes, paxlovid works on omicron where it reduced the risk of hospitals or deaths by as much as 44%.
pfizer ltd

Written By
Venika Choudhary
Medical Content Writer @ Magicine Pharma
I hold an M.Sc. in Microbiology and have a strong academic foundation in microbial sciences and applied biotechnology. I began my career with extensive hands-on research at CSIR laboratories, focusing on fungal enzyme production, studying fungal diversity in various ecosystems, and developing bio-pesticides as sustainable alternatives to chemical pesticides. This work deepened my understanding of fungal biology, bioactive compounds, and their pharmaceutical and agricultural applications. Transitioning from research, I now work as a medical content writer, where I combine my scientific expertise with a passion for clear and reliable healthcare communication. I apply my research background to create patient-friendly, compliant content for pharmaceutical companies and healthcare platforms, ensuring science is both trustworthy and accessible. Specializing in clear, accurate, and engaging content, I help patients make informed decisions and support pharmaceutical companies in delivering trusted information. Whether writing product descriptions, crafting disease awareness articles, or composing drug information leaflets, I consistently meet regulatory standards and address audience needs, making my content an asset for healthcare brands.

Reviewed By
Dr. Aditya Sarin - MBBS, MD, DrNB - Consultant Medical Oncology
Dr. Aditya Sarin, MBBS, MD, DrNB, is a highly qualified medical oncologist with profound research and clinical expertise, currently working at Sir Ganga Ram Hospital, New Delhi. He is also a member of the European Society of Medical Oncology (ESMO), a non-profit European organization dedicated to eradicating cancer by promoting comprehensive cancer care and advancing medical oncology. He has been honored with several awards, including the International Cancer Foundation scholarship (ESMO congress, 2022) and Young Medical Oncologist of the Year (Times of India, 2024). He is well-known for his breakthrough in oncology. Dr. Sarin is passionate about converting complex health information into a concise and clear form that is understandable to everyone, aiming to create awareness and cancer care among people.