Brand name - Sofocure
Generic name - Sofosbuvir
Manufacturer - Emcure
Salt composition - Sofosbuvir
Storage - Store at room temperature (10-30°C)
Dosage form - Oral (Tablet)
Strength - 400mg + 100mg
Packaging - Bottle of 28 tablets
Gender - Unisex
Active ingredient - Sofosbuvir
Prescription required - Yes
Indication - Used in the treatment of chronic hepatitis C virus (HCV) infection
Sofocure (sofosbuvir 400mg) is an antiviral medicine. This medicine is used with other medications in the treatment of chronic (long-lasting) Hepatitis C Virus infection in adults. Sofocure should be taken exactly as prescribed by the healthcare provider (in dose and duration). It works by lowering the multiplication of the virus and helps in the removal of virus from the blood over a period of time.
Sofosbuvir inhibits the hepatitis C NS5B protein. Sofosbuvir appears to have a high barrier to the development of resistance. Sofosbuvir is a prodrug of the Protide type, whereby the active phosphorylated nucleotide is granted with cell permeability and oral bioavailability. By hydrolysis of the carboxylate ester by either of the enzymes cathepsin A or carboxylesterase 1, Sofosbuvir is activated in the liver to the triphosphate GS-461203 followed by cleaving of the phosphoramidate by the enzyme histidine triad nucleotide-binding protein 1 (HINT1), along with repeated phosphorylation. Dephosphorylation then creates the inactive metabolite GS-331077. The half life of Sofosbuvir is 0.4 hours, and the half life of GS-331077 is 27 hours. Following a single 400 mg oral dose of sofosbuvir, 80% is normally excreted in urine, 14% in feces, and 2.5% in expired air recovery.
The active ingredient of Sofocure is Sofosbuvir. The inactive ingredients of Sofocure are colloidal silicon dioxide, croscarmellose sodium, magnesium stearate, mannitol, and microcrystalline cellulose.
Usage of medicine
Sofocure (Sofosbuvir) is used with other medications in the treatment of chronic (long-lasting) Hepatitis C Virus infection in adults.
Shortness of breath
Take Sofocure (Sofosbuvir 400mg) exactly as your healthcare provider tells you. Do not alter the dose strength. Do not chew, crush or break the tablet. Swallow the tablet as a whole.
Take the dose as soon as possible, if you miss the dose. However, if it is already the time for the next dose, do not take the missed dose. Do not double up the dose to catch up.
Seek emergency medical attention.
Warning and precautions
Avoid consumption of alcohol.
If you have liver disease, tell your healthcare provider about the same before taking this medicine.
If you have kidney disease, dose alteration may be needed. Therefore, make sure to tell your doctor about the same before taking Sofocure.
Tell your healthcare provider about your medical history and the medicines you take already.
During pregnancy, it is important to consult a doctor before taking any medicine. Make sure to do so in case of this medicine also.
Sofocure 400mg is safe for use during breastfeeding only if prescribed by the healthcare provider.
Q1- What is Sofocure?
A- Sofocure is an antiviral medication, used with other medicines to treat chronic Hepatitis C Virus.
Q2- How should I take Sofocure?
A- Take Sofocure exactly as your healthcare provider tells you. Do not alter the dose, unless your healthcare provider tells you.
Q3- What are the possible side effects of Sofocure?
A- There can be side effects such as fever, chills, diarrhea, dizziness, nausea, anemia, skin rash, itching and irritability. Please consult your healthcare provider if you experience these or any other side effects.
Q4- What are self care tips?
A- Drink plenty of water to stay hydrated.
Q5- What should I avoid consuming with this medicine?
A- Avoid consumption of alcohol.
Q6- In what strength is it available?
A- Sofocure tablet is available in the strength of 400mg.
Q7- What are the storage conditions?
A- Store at room temperature (10-30°C). Keep it away from children, direct light, heat and moisture.
Q8- Can I drive after taking this medicine?
A- Sofocure may cause side effects such as tiredness and blurred vision. Therefore, avoid driving and operating heavy machines if you feel unwell.
Q9- Can I take Sofocure during pregnancy?
A- Before taking any medicine during pregnancy, make sure to ask your healthcare provider.
Q10- Can I take Sofocure during breastfeeding?
A- Sofocure is safe during breastfeeding, only if prescribed.