INSTGRA

Mfd. by :- Emcure (Fulfilled By : Magicine Pharma)

Instgra

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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Brand name - Instgra
Generic name - Dolutegravir
Manufacturer - Emcure
Strength - 50 mg
Dosage - Tablet (Oral administration)
Packaging - Bottle
Indication - HIV infection

Description

Instgra 50 mg tablet is used in the treatment of HIV (Human Immunodeficiency Virus) infection. HIV is the virus that can cause AIDS (Acquired Immunodeficiency Syndrome). It is a prescription medicine. The active ingredient of Instgra tablet is Dolutegravir. It is a small molecule HIV-1intergrase inhibitor that works to block the strand transfer step of the integration of the viral genome into the host cell. 

This medication helps to lower the multiplication of the virus and eventually decreases the infection. It is not a permanent cure for HIV or AIDS. It also helps the patients to get rid of the HIV-related symptoms and attached complications. It may be prescribed with other medicines. It is advisable to take this medicine regularly (according to the doctor’s prescription) and not skip a dose unless the doctor tells you. This medicine is available at the best price in India.

Pharmacodynamics

Instgra, comprising Dolutegravir, is an HIV-1 antiviral agent. It works to inhibit HIV integrase and binds to the active site. It blocks the strand transfer step of retroviral DNA integration in the host cell. During the clinical trials, it was indicated that Dolutegravir has a tight binding and longer dissociative half-life. Therefore, it is indicated in combination with other antiretroviral agents for the treatment of patients with HIV-1 infection, provided their age is 12 or above and present weight is at least 40 kg.

Usage of medicine

Instgra tablet (50 mg) is used in the treatment of HIV (Human Immunodeficiency Virus). It is not a permanent cure but is used to prevent the multiplication of the virus in the body. It should be taken regularly at the right time. It is advisable to not skip the doses. Also, do not stop taking this medicine, unless your healthcare provider tells you. 

Interactions

Interaction with Alcohol

Interaction with alcohol is unknown. It is advisable to consult your healthcare provider before consumption.

Interaction with Medicines

  • Aluminium Hydroxide

  • Efavirenz

  • Phenytoin

  • Metformin

  • Dofetilide

Following are the side effects of Instgra tablet. Note that there can be other side effects also. Therefore, it is advisable to consult a medical practitioner if side effects occur or last longer than usual.

  • Headache

  • Insomnia

  • Dizziness

  • Nausea

  • Fatigue

  • Muscle pain

  • Skin rash

  • Itching

  • Fever

  • Chills

  • Sore throat

  • Mouth sores

  • Loss of appetite

  • Stomach ache

  • Difficulty in breathing

  • Muscle or joint pain

  • Yellowing of skin

  • Vomiting

  • Unusual tiredness

  • Swelling on face, hands, or legs

Normal Dose

Take Instgra tablet exactly in the same strength and duration as prescribed by your healthcare provider. Do not crush, break, chew or cut the tablet. Swallow it as a whole. Also, do not skip a dose.

Missed Dose

If you miss a dose, it is advisable to consult your healthcare provider to get the needed help. Also, make sure to not double the dose strength to catch up.

Overdose 

It is advisable to seek emergency medical attention in case of overdose.

  • Make sure to consult your healthcare provider regarding your medical history, medicines you already take, and allergies(if any).

  • Administer Instgra (Dolutegravir 50 mg) tablet with caution in patients having known kidney or/and liver disease.

  • During pregnancy or breastfeeding, make sure to discuss the potential risks and benefits of taking this medicine.

  • Limit your sugar and salt intake.

  • After taking Instgra (Dolutegravir 50 mg) tablet, avoid driving or operating heavy machinery if side effects like blurred vision or dizziness occur and last longer than usual.

Q1- What is Instgra 50 mg tablet used for?

A- Instgra (Dolutegravir 50 mg) tablet belongs to the class of drugs known as integrase inhibitors. It is prescribed for the treatment of HIV (Human Immunodeficiency Virus) infection. 

Q2- In what strength is it available?

A- Instgra tablet is available in the strength of 50 mg. 

Q3- What are the side effects of Instgra tablets?

A- The side effects of Instgra tablets are fever, chills, mouth sores, vomiting, stomach pain, yellowing of the skin or eyes, nausea, muscle or joint pain, loss of appetite, etc. Make sure to consult a medical practitioner 

Q4- Can I drive after taking this medicine?

A- After taking Instgra tablet, avoid driving or operating heavy machinery if side effects like blurred vision or dizziness occur and last longer than usual.

Q5- Can I take this medicine during pregnancy or breastfeeding?

A- During pregnancy or breastfeeding, taking Instga tablet may not be safe. Kindly consult your doctor to discuss the potential risks and benefits of taking this medicine.

Q6- What is the storage condition for Instgra 50 mg tablet?

A- Store Instgra tablet at room temperature (10-30°C). Keep it away from children and pets.

Q7- What should I avoid while consuming Instgra tablet?

A- Limit your sugar and salt intake because HIV may increase your chance of getting heart disease.

Q8- Can I take this medicine in liver disease?

A- Take Instgra tablet with utmost caution if you have known liver disease. Discuss with your doctor beforehand.

Q9- Can I take this medicine in kidney disease?

A- Take Instgra tablet with utmost caution if you have known kidney disease. Discuss with your doctor beforehand.

Q10- Is it a habit-forming medicine?

A- No, it is not a habit-forming medicine.

Above Content has been reviewed by Professionals