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Xbira 250mg Tablet

4.8
Google Rating

Prescription Required

Marketed By

cipla

Pack of

120 Tablets in Bottle

Salt Composition

Abiraterone Acetate

Storage

Keep in cold place

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Overview

  • Xbira 250mg Tablet is an anti-cancer medication used to treat adult male patients with metastatic prostate cancer who have reached their limit with regards to hormonal treatments and surgery.
  • Xbira 250mg Tablet targets the CYP17 enzyme, thereby lowering testosterone levels that fuel cancer growth. This form of chemotherapy is often administered in conjunction with steroids such as prednisone or prednisolone due to side effects such as hypertension, hypokalemia, and fluid retention.
  • Indications of Xbira 250mg Tablet include both metastatic castration-resistant prostate cancer (mCRPC) when the cancer becomes resistant to hormone therapy or surgical intervention and mHSPC in combination with androgen deprivation therapy (in the early stages).
  • Xbira 250mg Tablet should be taken orally without food, either at least one hour before or two hours after eating. Xbira 250mg Tablet is contraindicated for use by females and children.
  • Some side effects associated with this tablet include joint swelling, diarrhea, edema, fatigue, and hypertension.

Indication

Prostate Cancer

Uses


  • ​Metastatic Castration-Resistant Prostate Cancer (mCRPC)
  • Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)

Side Effects

  • There are various side effects of consuming the Xbira 250mg tablet. They may vary from person to person depending on the health and age of the person. Consult your doctor immediately in case these side effects worsen. 
  • Swelling of a joint
  • General discomfort
  • Low potassium levels in the blood (may cause muscle weakness, twitches, or pounding heartbeat)
  • Swelling (legs, feet, or other areas)
  • Frequent urination at night
  • Indigestion
  • Muscle pain
  • Fluid buildup in legs or feet
  • High blood pressure
  • Urinary tract infection
  • Diarrhea
  • High fat levels in the blood (dyslipidemia)
  • Chest pain
  • Irregular heartbeat
  • Rapid heart rate
  • Bone fracture
  • ​Blood in urine
  • ​Rash

How To Use


  • The doctor determines the dosage of Xbira 250mg Tablet as per the patient's health and other medical conditions.
  • Take it at a fixed time every day exactly as prescribed by the doctor to get effective results.
  • This medicine should be taken orally on an empty stomach.
  • Avoid breaking the tablets by swallowing them whole with water.
  • Pregnant or potentially pregnant women should not handle this medicine without gloves.
  • In case of an overdose, contact your doctor immediately

How It Works


  • Xbira 250mg Tablet is an anticancer medicine prescribed to treat prostate cancer.
  • It works by blocking the action of an enzyme called CYP17.
  • This enzyme is involved in the production of the male hormone androgen, as some prostate cancer depends on these hormones to grow, and this medicine effectively slows down or stops the progression of cancer by inhibiting the action of this enzyme.
  • In this way this tablet cuts off the fuel supply that the cancer cells need to survive.

Safety Advice

Alcohol

UNSAFE

It is advisable not to consume alcohol while taking medicine. The safety of using Xbira 250mg Tablets while drinking alcohol is unknown. Before taking this drug, speak with your doctor.

Pregnancy

UNSAFE

Do not consume Xbira 250mg tablet in case of pregnancy because this medicine is especially designed to treat male-related cancers.

Breast Feeding

UNSAFE

Do not take this medicine if you're breastfeeding because this medicine is especially designed to treat male-related cancers.

Driving

DANGER

It is advisable not to drive or operate heavy machinery, you may feel dizzy as one of the side effects of the medicine.

Kidney

PRECAUTION

Do not consume Xbira 250mg tablet without consulting your doctor in case of kidney problems.

Liver

PRECAUTION

Share your medical history with the doctor in case of liver disease. Before taking Xbira 250mg Tablet, discuss any liver conditions you may have with your doctor. Patients with severe liver issues should not use this drug.

Missed Doses

  • In case of a missed dose, contact your healthcare provider. 

Quick Tips

  • Inform the doctor about your medical history of liver problems, blood pressure, heart disorders, diabetes, or taking any medication for these medical conditions.
  • Xbira 250mg Tablet is used in adult men to treat advanced prostate cancer that has spread, often together with prednisone to reduce side effects. Always pair it with prednisone to prevent adrenal insufficiency.
  • Take this medicine as prescribed by your doctor, once daily on an empty stomach; food can increase medicine levels.
  • It may be combined with testosterone-lowering treatment in earlier stages of prostate cancer.
  • Serious risks include adrenal insufficiency, liver toxicity, heart problems, and bone fractures; regular monitoring is essential.
  • Liver function tests are required before starting the treatment and then regularly.
  • This medicine is not for women or children; men must use contraceptives during treatment and after stopping.
  • Inform your doctor if you have liver problems, heart disease, high blood pressure, diabetes, allergies, or low potassium.
  • Tell your doctor about all medicines, supplements, and herbal products you are taking.
  • Since it contains lactose and sodium, let your doctor know if you have lactose intolerance or are on a salt-restricted diet.

FAQs

What is the use of Xbira 250mg tablet ?

Xbira 250mg tablet is used to treat men with prostate cancer.

What are the possible side effects of Xbira 250mg Tablet?

There can be side effects like high blood pressure, fever, dizziness, diarrhea, fast heartbeat, headache, weakness, and swelling in the legs. There can be some other side effects also. Therefore, make sure to contact your healthcare provider regarding the same.​

What are the storage conditions for Xbira 250mg Tablet?

Store at room temperature (10-30°C). Keep it away from children and pets.

Is it safe to consume Xbira 250mg Tablet during pregnancy and breastfeeding?

Xbira 250mg Tablet is a highly unsafe medicine to use during pregnancy and breastfeeding, as it can fall harmful effects on a developing baby. Also, it is especially designed to treat male conditions.

What is the strength of Xbira 250mg Tablet?

The medicine is available in 250mg strength. 

How Xbira 250 mg tablet should be taken?

The Xbira 250mg Tablet should be taken on an empty stomach and as directed by the physician. The patient is recommended to eat one hour after taking the drug, and food must be consumed at least two hours before taking it.

Is Xbira 250mg Tablet a medication used in chemotherapy?

No, Xbira 250mg Tablet is a hormonal treatment for prostate cancer rather than a chemotherapy medication. It slows the growth of prostate cancer by blocking the production of testosterone.

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References

  • Apothecare Wellness. (n.d.). Buy Xbira 250 mg Tablet Online: Uses, Price, Dosage, Side Effects. Retrieved from the Apothecare website Fizazi, K., Scher, H. I., Molina, A., Logothetis, C. J., Chi, K. N., Jones, R. J.,  & de Bono, J. S. (2012).
  • Abiraterone acetate for treatment of metastatic castration‑resistant prostate cancer: Final overall survival analysis of the COU‑AA‑301 randomized, double‑blind, placebo‑controlled phase 3 study. Lancet Oncology, 13(10), 983–992 - https://pubmed.ncbi.nlm.nih.gov/22995653/
  • James, N. D., de Bono, J., Spears, M., Clarke, N. W., Mason, M. D., Dearnaley, D. P., & Attard, G. (2017).
  • Abiraterone plus prednisone in metastatic, castration-sensitive prostate cancer. New England Journal of Medicine, 377(4), 352–360 - https://pubmed.ncbi.nlm.nih.gov/28578607/
  • Practo. (n.d.). Xbira 250 mg Tablet – Uses, Dosage, Side Effects, Price, Composition. Retrieved from Practo (Indian healthcare platform).
  • Ryan, C. J., Smith, M. R., de Bono, J., Molina, A., Logothetis, C. J., de Souza, P., & Scher, H. I. (2013). Abiraterone in metastatic prostate cancer without previous chemotherapy. New England Journal of Medicine, 368(2), 138–148.
  • Tan, G., Xuan, Z., Li, Z., Huang, S., Chen, G., Wu, Y., & Liang, Z. (2020). The efficacy and safety of abiraterone acetate in patients with high‑risk prostate cancer: A meta‑analysis based on six randomized controlled trials. Translational Andrology and Urology, 9(4), 1691–1699.

Ratings And Reviews

4.8
Google Rating

4.67/5

6 Ratings

5

66.67%

4

33.33%

3

0.00%

2

0.00%

1

0.00%

Sophia Martin

Very satisfied with purchase

Very happy with Xbira 250mg Tablet! The quality is top-notch and it's been serving me well. The delivery was quick and packaging was intact. Overall, a great experience and I would definitely order again.

a year ago

Ravi Gupta

Impressed with the quality

Great product! Xbira 250mg Tablet has been working perfectly for me. The quality feels reliable and the value for money is excellent. Delivery was on time and packaging was good. Very satisfied with my purchase.

a year ago

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MARKETER DETAILS

cipla

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The contents of this website are for informative purposes only. They are not deliberated to be an alternative to any professional medical prescription and treatment. Seek the advice of a qualified health provider for questions regarding the medical condition. Do not ignore any professional medical advice because of something you have read on this website. This website offers links to other websites, thereby enabling you to go to the other website directly. Therefore, Magicine Pharma isn't responsible for the content of the links in the website or links in the linked websites. The links are provided to assist the visitors and are not approved by any professional health provider.