What precautions are taken while using Acabrunat 100mg capsule?

Pregnant and breastfeeding women should avoid taking Acabrunat 100mg capsule, people with previous medical history, regular checkups are necessary to ensure the safety and effectiveness of the treatment.

Is Acabrunat 100mg capsule show any side effects after taking it?

Yes, like any other medications Acabrunat 100mg injection also show various common as well as severe side effects, id patients experience any of these consult the doctor immediately.

Can I take Acabrunat 100mg injection with other medication?

Take guidance with healthcare expert before taking Acabrunat 100mg injection with any other medication, including prescription drug to ensure safety and effectiveness.

What is the salt composition of Acabrunat 100mg injection?

Salt composition of Acabrunat 100mg injection is Acalabrutinib, which is the active ingredient responsible for the anticancer effects by preventing the growth and survival malignant B cells.

Buy Acabrunat 100mg Capsule Online: Price, 40% Discount, Uses, and Side Effects

Name: Acabrunat 100mg Capsule
Brand: Acabrunat
Price: 8710 INR
Availability: InStock
Rating: 5 (7 reviews)

Description

Acabrunat 100mg capsule is an anti-cancer medication used in the treatment of treat mantle cell lymphoma (MCL), chronic lymphocytic leukemia (CLL), and small lymphocytic lymphoma (SLL) and other disorders involving abnormal white blood cells that are the part of immune system. The medicine’s active ingredient is Acalabrutinib in the form of 100mg and belongs to the therapeutic class of Tyrosine Kinase Inhibitor (TKI).

Acabrunat 100mg capsule works by inhibiting Bruton’s tyrosine kinase (BTK), a protein that plays role in growth and survival of malignant B cells. By blocking the protein, the medicine helps to slow down or stop progression of cancer cells in the body.

Indication

Mantle cell lymphoma, small lymphocytic lymphoma and chronic lymphocytic leukemia

Common side effects

Medications show side effects as they act on multiple pathways in the body, just like that Acabrunat 100mg capsule may also cause certain side effects because it affects not only cancerous B cells but can also influence normal cells involved in immune and blood functions.
Some of them are: ● Anaemia ● Low blood platelets ● Headache ● Diarrhea ● Decreased white blood cell count ● Upper respiratory tract infections ● Musculoskeletal pain

Dosage and administration

The capsule can be taken orally, twice a day usually with or without food exactly as prescribed by the healthcare provider to ensure proper absorption and effectiveness.
Do not skip the medication, and if a dose is missed, try to take it as soon unless it’s time for the next dose but never double up the dose to make up for the missed one.

Mechanism of action

Acabrunat 100mg capsule works by inhibiting Bruton’s tyrosine kinase (BTK), it disrupts the signaling pathways that cancerous B cells use to survive, this slow down or stops the growth and spread of cancer cells.

This improves the function of immune system to fight against abnormal cells more effectively and helping to control the progression of the disease.

Safety advice

Alcohol

Alcohol is not recommended to the patient of blood cancer or who are taking Acabrunat 100mg capsule, as it can increase the risk of liver damage and worsen the side effects.

Driving

Patient should avoid driving or operating machine while using Acabrunat 100mg capsule if they experience any side effects such as fatigue, dizziness and blurred vision.

Pregnancy

Acabrunat 100mg capsule is not prescribed to pregnant women as it harms the developing fetus. Women who are pregnant or planning to become pregnant should avoid taking this medicine.

Breast Feeding

Breastfeeding women should avoid taking Acabrunat 100mg capsule, as the drug may pass into breast milk and could harm nursing infant.

Kidney

Kidney patients are not recommended to take Acabrunat 100mg capsule as it can increase the risk of side effects.

Liver

Patient with liver problems should not be suggested to take Acabrunat 100mg capsule as reduced liver functions and interfere with the metabolism of the drug.

FAQs

The injection is a prescription based medication used in the treatment of several blood cancers such as Mantle cell lymphoma, chronic lymphocytic leukemia (CML) and Small Lymphocytic leukemia (SLL).

Reference

• Yadav, B. A., & Kuchana, V.

(2024). Analytical method development and validation for the estimation of acalabrutinib in API form and marketed pharmaceutical dosage form by RP-HPLC along with stability studies. • Wu, J., Zhang, M., & Liu, D.

(2016). Acalabrutinib (ACP-196): a selective second-generation BTK inhibitor.

Journal of hematology & oncology, 9(1), 21. • Markham, A., & Dhillon, S. (2018).

Acalabrutinib: first global approval. Drugs, 78(1), 139-145. • Byrd, J.

C., Harrington, B., O’Brien, S., Jones, J. A., Schuh, A., Devereux, S., ... & Furman, R.

R. (2016).

Acalabrutinib (ACP-196) in relapsed chronic lymphocytic leukemia. New England Journal of Medicine, 374(4), 323-332. • Brown, J.

R., Seymour, J. F., Jurczak, W., Aw, A., Wach, M., Illes, A., ... & Ghia, P.

(2025). Fixed-duration acalabrutinib combinations in untreated chronic lymphocytic leukemia.

New England Journal of Medicine, 392(8), 748-762.

Acabrunat 100mg Capsule

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