Acalaside 100mg Capsule

Acalaside 100mg Capsule

Prescription requiredRx Required

Salt Composition: Acalabrutinib

Expiry Date: 01/2028

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$258.82

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30 capsule(s) in a bottle

About The Product

mantle cell lymphoma, chronic lymphocytic leukemia, small lymphocytic lymphoma

Description

Acalaside100mg capsule is used in the treatment of mantle cell lymphoma, chronic lymphocytic leukemia and small lymphocytic lymphoma. It contains an active ingredient of Acalabrutinib which belongs to the class of Tyrosine kinase inhibitors.

The medicine works by blocking Bruton’s tyrosine kinase (BTK) that help the cancerous B cells to grow and survive, it slows down the growth or stop the growth of cancer cells in the body. Doctors prescribed this medication as a part of targeted therapy for blood cancer to control the disease and improve patient outcomes.

Indication

Mantle cell lymphoma, chronic lymphocytic leukemia and small lymphocytic lymphoma

Common Side effects

  • Medications show various side effects depending on how an individual’s body responds to the treatment.
  • Consult the doctor if any of the symptoms persist while using Acalaside 100mg capsule.
  • Common side effects include: ● Fatigue ● Diarrhea ● Anaemia ● Upper respiratory tract infection ● Neutropenia (Low neutrophill count) ● Headache ● Musculoskeleton pain

Dosage and administration

  • Acalaside 100mg capsule should be taken orally; healthcare experts mostly prefer with food or between meals, it is better to take it at the fixed time everyday to enhance the effectiveness of the medication.
  • The medicine takes several weeks to show a noticeable response so it is important to take it as prescribed and follow up regularly with the doctor.

Mechanism of action

The body contains bruton’s tyrosine kinase (BTK) which interfere with the B cell receptor signaling pathway and when they goes out of control, B cells can reproduce at an uncontrolled rate and lead to lymphoma.

Acalaside 100mg capsule blocks the Bruton’s tyrosine kinase (BTK) enzyme, it helps to slow or stop the progression of cancer growth in the body.

Safety advice

Alcohol
When patients use Acalaside 100mg capsule for various types of blood cancer, it is necessary to avoid alcohol, smoking and drug to ensure safety and effectiveness of the treatment.
Driving
Patients who experience dizziness, sleepiness and fatigue during the treatment with Acalaside 100mg capsule should avoid driving and operate machinery or performing any activities that require full alertness until these symptoms are not completely gone.
Pregnancy
Women who are pregnant or planning to be pregnant should avoid using Acalaside 100mg capsule as it can harmful for the developing fetus.
Breast Feeding
Acalaside 100mg capsule is not prescribed to breastfeeding women, as it may into breast milk and harm the baby. Discuss with the healthcare provider for safe alternative and guidance on temporarily stopping breast feeding during treatment.
Kidney
Doctor do not suggest to take Acalaside 100mg capsule with severe kidney problems as impaired kidney function and make the patient more prone to side effects or toxicity.
Liver
Acalaside 100mg capsule is not prescribed for liver patients because the medication could harm the patients in various forms.

FAQs

The tablet is used orally in the form of 100mg indication as prescribed by the healthcare provider.

Acalaside 100mg capsule should be taken twice a day with or without food at the same time every day.

Reference

• Wolska-Washer, A., & Robak, T. (2022).

Acalabrutinib: a bruton tyrosine kinase inhibitor for the treatment of chronic lymphocytic leukemia. Expert Review of Hematology, 15(3), 183-194. • Byrd, J.

C., Wierda, W. G., Schuh, A., Devereux, S., Chaves, J.

M., Brown, J. R., ... & Furman, R.

R. (2020).

Acalabrutinib monotherapy in patients with relapsed/refractory chronic lymphocytic leukemia: updated phase 2 results. Blood, The Journal of the American Society of Hematology, 135(15), 1204-1213. • Wang, M., Rule, S., Zinzani, P.

L., Goy, A., Casasnovas, O., Smith, S. D., ... & Jurczak, W.

(2018). Acalabrutinib in relapsed or refractory mantle cell lymphoma (ACE-LY-004): a single-arm, multicentre, phase 2 trial.

The Lancet, 391(10121), 659-667. • Awan, F. T., Schuh, A., Brown, J.

R., Furman, R. R., Pagel, J.

M., Hillmen, P., ... & Byrd, J. C.

(2019). Acalabrutinib monotherapy in patients with chronic lymphocytic leukemia who are intolerant to ibrutinib.

Blood advances, 3(9), 1553-1562. • Byrd, J. C., Woyach, J.

A., Furman, R. R., Martin, P., O’Brien, S., Brown, J.

R., ... & Wierda, W. G.

(2021). Acalabrutinib in treatment-naive chronic lymphocytic leukemia.

Blood, The Journal of the American Society of Hematology, 137(24), 3327-3338.

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