Mfd. by :- Gentech (Fulfilled By : Magicine Pharma)
Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.
Brand Name:- Alecensa
Generic Name:- Alectinib
Manufacturer:- Gentech
Dosage Form:- Capsules
Strength:- 150mg
Composition:- Alectinib
Packaging:- 240 capsules
Indication:- Lung cancer
Storage Conditions:- Store at room temperature
Alectinib 150mg Capsule is a prescription medicine used in the treatment of non-small cell lung cancer that has spread from your lungs to other parts of your body and is caused by an abnormal anaplastic lymphoma kinase ALK gene. Alectinib 150mg Capsule contains the active drug alectinib, which is an ALK inhibitor. It shows its action by blocking receptors found on cancer cells eventually inhibiting the growth of cancer cells. This type of drug is commonly used to treat specific types of cancer. Alectinib 150mg Capsule comes in the form of capsules that are taken orally twice a day with food.
When taken with food, Alecensa reaches peak concentrations approximately 4 hours after dosing. It is metabolized by CYP3A4 to the active metabolite M4. Alectinib 150mg Capsule targets downstream communication and protein signaling that results from ALK phosphorylation and ALK-mediated activation. This is how Alectinib 150mg Capsule inhibits the growth of cancer cells.
Alectinib 150mg Capsule can cause some unwanted side effects :-
Chest pain
Increased blood pressure
Bloody urine
Anemia
Constipation
Joint pain
Loss of appetite
Muscle and bone pain
Weakness
Vomiting
Weight gain
Nausea
Dizziness
Skin rash
Allergic reaction
Bloody stools
Fever
Headache
Irregular heartbeat
Bloating
Blurred vision
Kidney damage
Liver damage
Vision problem
Muscle weakness
Hyperglycemia
Pancreatitis
Note- immediately contact your doctor,if any of these symptoms occurs
Alecensa comes in the form of capsules that are taken by mouth. It should be taken twice a day with food.
In case you miss a dose immediately contact your doctor. Do not double the dosage to make up for the missed dose.
Emergency medical treatment required or contact your doctor in case of an overdose.
Before using Alectinib 150mg Capsule , inform your doctor about medical history.
Contraception
Use reliable methods of contraception to prevent pregnancy while taking Alectinib 150mg Capsule.
Children and adolescents
Alectinib 150mg Capsule is not for use in children and adolescents
Pregnancy
Alectinib 150mg Capsule shouldn’t be used by women who are pregnant. This medicine may cause harm to human fetuses. It is recommended that drugs should be avoided during pregnancy.
Breastfeeding
This medicine should not be used by women who are breastfeeding.
Before starting treatment with Alecensa, make sure you tell your doctor about any other medications you are taking.
Tell your doctor if you have any history of kidney or liver problems.
If you have lung problems or breathing problems. Do not take Alectinib 150mg Capsule without your doctor's advice.
If you have a slow heart rate, Alecensa can worsen your condition.
Do not chew this medicine
Not safe for pregnant women
May harm liver
It’s possible to have bradycardia
AnsAlectinib 150mg Capsule is a cancer medicine that interferes with the growth and spread of cancer cells in the body. It is used to treat a certain type of lung cancer that has spread to other parts of the body.
Ans. Alectinib is a tyrosine kinase inhibitor (TKI). Tyrosine kinases are specific enzymes (a type of protein) that may signal cancer cells to grow. TKIs block these cell signals and by barricading the signals, they prevent the growth of the cancer cells. Alectinib blocks the abnormal ALK (anaplastic lymphoma kinase) protein.
Ans. Some common side effects of Alectinib 150mg Capsule are :- vomiting, constipation, chest pain, joint pain, shortness of breath, muscle and bone pain, weakness, fever, weight gain, swelling, skin rash, slow heart rate.
Ans. It is available in the strength of 150mg.
Ans. You should try to avoid sunlight because Alecensa may make your skin more sensitive to sunlight. While you’re taking this medication you may get severe sunburns. Because of this, you should use sunscreen with at least SPF50. Doing this will help to protect you from sunburn.
Ans. It should be taken orally by mouth twice a day with food. One should take Alectinib 150mg Capsule according to their doctor's instructions.
Ans. No, this is not chemotherapy. Alecensa is a type of targeted therapy that works only on specific cells in your body.
Ans. Immediately contact your doctor in case you miss a dose.
Ans. This medication is not recommended for pregnant women, it may cause harm to the unborn baby.
Ans. It is not known whether it is safe or not. Please consult your doctor.
Ans. This medicine should not be used by women who are breastfeeding.
Ans. Alecensa capsules should be stored at room temperature.
Ans. Keep yourself hydrated while taking this medicine. Avoid sun exposure and crowded places. Maintain good nutrition.
Ans. It may cause dizziness which may affect your ability to concentrate.
Before taking Alecensa capsules, talk with your doctor and tell them about all prescriptions and other drugs you take.
Avastin
Digoxin
Atazanavir
Enbrel
Tacrolimus
Fluconazole
Celexa
Eliquis
Norco
Protonix
Hepatic impairment
Renal impairment
Lung toxicity
Bradycardia
Interaction with alcohol is unknown. Before consuming alcohol, please consult your doctor.
None.
Reference
Alectinib: Mechanism, side effects, and dosage are available at: - https://medlineplus.gov/druginfo/meds/a616007.html, https://www.cancerresearchuk.org/about-cancer/treatment/drugs/alectinib, and https://www.webmd.com/drugs/2/drug-170682/alectinib-oral/details