Ciclib 100mg Capsule

Ciclib 100mg Capsule

Prescription requiredRx Required

Salt Composition: Palbociclib

Expiry Date: 01/2028

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21 Capsule in Box

About The Product

Breast Cancer, Metastatic Cancer


Description

Ciclib 100mg tablet is a prescription based anti-cancer medication. It is used in the treatment of certain types of breast cancer (estrogen receptor positive and human epidermal growth factor receptor 2 negative).

Its active ingredient is Palbociclib belongs to the drug class of CDK4/6 inhibitors. It works by blocking the CDK4 and CDK6 enzymes which are responsible for the growth of cancer cells.

The medicine also prevents the body from further growing cancer in the body. Strict medical supervision is highly recommended in the as the medicine is not prescribed adults under the age of 18.​

Uses

  • Breast cancer, metastatic cancer

Side Effects

Every medication has several side effects, like Ciclib 100mg tablet. Patients experience several side effects, some of them resolve on their own and some need proper medical attention. Common symptoms include:

  • Dry skin, rash
  • Infections
  • Low blood cell counts
  • Decreased of appetite
  • Nausea, vomiting
  • Diarrhea
  • Swelling of lips and mouth
  • Changes in taste
  • Nose bleed

  • Dry eye, blurred vision, increased tearing

  • Tiredness
  • Hair loss

How To Use

  • Ciclib 100mg tablet should be taken with food, at the fixed time everyday. Do not miss or skip the medication as consistency is key, regular intake can increase the effectiveness of the medication.
  • Taking it in the wrong way, allows cancer cells to grow and increases the risk of side effects or complications. Always follow the doctor's instructions carefully.​​

How It Works

  • Breast cancer is formed when normal blood cells undergo DNA changes, causing them to undergo uncontrollably, divide excessively and form a tumor. CDK4 and CDK 6 enzyme is a primary reason which is responsible for the formation of cancer cells in the body.
  • Ciclib 100mg tablet contains CDK 4/6 inhibitor that block the DNA mutation and slow the disease progression of the treatment.​​

Safety Advice

Alcohol
Taking Ciclib 100mg tablet with alcohol may be dangerous to the patient's health but consult the doctor before taking the medication.
Pregnancy
Ciclib 100mg tablet is not recommended to pregnant and breastfeeding women as it may affect the fetus or newborn. Take guidance from a healthcare expert to ensure safety and precautions.
Breast Feeding
Breastfeeding women should not be advisable for taking Ciclib 100mg tablet as the medicine is passed through breast that somehow affect breast milk. Discuss with the doctor for more query.
Driving
Ciclib 100mg tablet may not cause dizziness or sleepiness but patient may still experience some side effects. It is important to monitor the response of medication and report any unusual symptoms to the doctor.
Kidney
Kidney patients should take precautions while using Ciclib 100mg tablet as dose adjustment and doctor's prescription is much needed.
Liver
Ciclib 100mg tablet may interrupt with liver function. Patients with liver disease should consult the doctor before using it.

FAQs

Ciclib 100mg tablet treats breast cancer in adult men by blocking the progression of androgen hormones which is responsible for the production of cancer cells in the body.

References

  • Turner, N. C., Ro, J., André, F., Loi, S., Verma, S., Iwata, H., ... & Cristofanilli, M. (2015). Palbociclib in hormone-receptor–positive advanced breast cancer. New England Journal of Medicine, 373(3), 209-219. https://pubmed.ncbi.nlm.nih.gov/26030518/
  • Cadoo, K. A., Gucalp, A., & Traina, T. A. (2014). Palbociclib: an evidence-based review of its potential in the treatment of breast cancer. Breast Cancer: Targets and Therapy, 123-133. https://pubmed.ncbi.nlm.nih.gov/25177151/
  • Serra, F., Lapidari, P., Quaquarini, E., Tagliaferri, B., Sottotetti, F., & Palumbo, R. (2019). Palbociclib in metastatic breast cancer: current evidence and real-life data. Drugs in context, 8, 212579. https://pubmed.ncbi.nlm.nih.gov/31391852/
  • Wedam, S., Fashoyin-Aje, L., Bloomquist, E., Tang, S., Sridhara, R., Goldberg, K. B., ... & Beaver, J. A. (2020). FDA approval summary: palbociclib for male patients with metastatic breast cancer. Clinical Cancer Research, 26(6), 1208-1212. https://pubmed.ncbi.nlm.nih.gov/31649043/
  • Turner, N. C., Slamon, D. J., Ro, J., Bondarenko, I., Im, S. A., Masuda, N., ... & Cristofanilli, M. (2018). Overall survival with palbociclib and fulvestrant in advanced breast cancer. New England journal of medicine, 379(20), 1926-1936.

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