COMETRIQ

Mfd. by :- Exelixis (Fulfilled By : Magicine Pharma)

Cometriq

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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Brand Name: Cometriq  

Generic Name: Cabozantinib  

Manufacturer: Exelixis  

Dosage Form: Capsules  

Strength: 100mg  

Composition: Cabozantinib  

Packaging: Blisters pack  

Indication: Kidney, Thyroid, and liver cancer 

Storage: Store at room temperature 

Overview  

Cometriq (cabozantinib) is used to treat certain types of cancer (kidney, thyroid, and liver cancer). It works by slowing or stopping the growth of cancer cells. The recommended dose of medicine is decided by the doctor. Medicine interferes with the growth of cancer cells, which are eventually destroyed by the body. Comteriq medicine comes in the form of a capsule. Your doctor will decide the dosing schedule according to your medical condition and your response to the treatment. Do not take this medicine in the wrong way as it may lead to some severe side effects. Inform your medical advisor if you are using any other medications. Do not crush or chew the capsule.  

Pharmacodynamics of Cometriq (Cabozantinib)   

Cabozantinib suppresses metastasis, angiogenesis, and oncogenesis by inhibiting receptor tyrosine kinases. After oral administration, the effect of this medicine can be observed in 2-5 hours. 

Usage of Cometriq (Cabozantinib) 

Cometriq medicine is available in the form of capsules. Take this medicine regularly at the same time to get the most benefit from it. Cabozantinib belongs to the class of drugs known as tyrosine kinase inhibitors. This medication works by blocking signals that allow cancer cells to grow and multiply. It is also used to treat advanced kidney and thyroid cancer that has spread to other parts of the body. Consult your doctor immediately if you experience any symptoms during treatment with this medicine. This medication may take some time to show results. Do not skip or miss the dosing schedule. It is important to take this medicine exactly as prescribed by your medical advisor. This medicine is not recommended in pregnant women. Store this medicine at room temperature. Protect it from moisture and heat.  

 

Side effects of Cometriq  

This medicine may cause some major and minor side effects. Discuss the risks and benefits of this medication with the doctor before starting the treatment.  

Common side effects  

  • Blurred vision  

  • Diarrhea  

  • Nausea  

  • Vomiting  

  • Constipation  

  • Fainting  

  • Headache  

  • Mouth sores  

  • Stomach pain  

  • Irregular heartbeat  

  • Weight loss  

  • Back pain  

  • Seizures  

  • High blood pressure  

  • Muscle pain  

  • Loss of taste  

  • Indigestion  

  • Cough  

  • Fatigue  

  • Jaw pain  

  • Shortness of breath  

  • Pale skin  

  • Dehydration  

  • Loss of appetite  

  • Poor wound healing  

  • Lightheadedness  

  • Dizziness  

  • Nosebleeds  

  • Skin rash  

  • Blood clots  

  • Loss of coordination  

  • Sunken eyes  

  • Pounding in the ears  

  • Dry skin  

  • Hair loss  

  • Easy bruising  

  • Swelling in your ankles and feets 

Note- please contact your doctor if any side effects occur 

Dosage of Cometriq

Take this medicine as prescribed by your doctor. Do not crush or chew the capsule. Take this medicine on an empty stomach one hour before or two hours after the meals.  

Missed dose  

  •  It is advisable not to miss a dose. If you miss a scheduled dose of this medicine, contact your doctor immediately.  

Overdose  

  • In case of an overdose, the doctor will provide emergency medical treatment.  

Warnings of Cometriq

Before starting treatment with the Cometriq capsule, do not forget to discuss your previous medical history with your doctor. If you experience any symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk.  

 Contraception  

  • Use effective methods of contraception to prevent pregnancy while taking this medicine.  

  • Children and adolescents  

  • This medicine is not advisable for use in children and adolescents.  

Warnings for female  

Pregnancy  

  • Do not use Cometriq if you are pregnant or planning to become pregnant. Avoid this medication at the time of pregnancy.  

Breastfeeding  

  • This medicine is not recommended in breastfeeding unless it is necessary. Please consult your medical advisor before starting treatment with this medication. 

Precautions of Cometriq

  • This medication delays wound healing.  

  • Do not take this medicine with food.  

  • Avoid the use of grapefruit products while taking this medicine.  

  • Do not breastfeed while taking this medicine.  

  • This drug may cause dizziness.  

  • Before starting treatment tell the doctor about your previous medical history.  

  • Do not receive any vaccinations without consulting with your doctor. 

Cautions of Cometriq

  • Do not crush, chew, or break the capsule.   

  • Do not drive or operate heavy machinery.  

  • Not safe for pregnant women.  

  • Do not breastfeed while receiving this medication.

Q1. What is Cometriq (Cabozantinib)?  

Ans. Cometriq (cabozantinib) is used to treat certain types of cancer (kidney, thyroid, and liver cancer). This medication works by slowing or stopping the growth of cancer cells. 

Q2. How does Cometriq (Cabozantinib) work?  

Ans. Cometriq medicine works by blocking signals that allow cancer cells to grow and multiply.  

Q3. What are the common side effects?  

Ans. Some common side effects are:- Anemia, blurred vision, dizziness, fever, dehydration, loss of appetite, nausea, diarrhea, irregular heartbeat, etc.  

Q4. In what strength is it available?  

Ans. It is available in the strength of 60mg, 100mg, 140mg.  

Q5. What should I avoid while receiving this medicine?  

Ans. Avoid the use of grapefruit products while taking this medicine.  

Q6. What are the self-care tips?  

Ans. Maintain good nutrition and get plenty of rest. 

Q7. What happens if I miss a dose?  

Ans. If you miss a scheduled dose of this medicine, contact your doctor immediately. 

Q8. Can I consume alcohol while taking this medicine?  

Ans. It is not known whether it is safe or not. Please consult your doctor before consuming alcohol. 

Q9. Can I drive after taking this medicine?  

Ans. This medicine may affect your vision. Do not drive if any symptoms occur.  

Q10. Can I take this medicine during pregnancy? 

Ans. This medicine is not recommended for pregnant women.  

Q11. What are the storage conditions?  

Ans. Store this medicine at room temperature.  

Q12. How to take this medicine?  

Ans. Take this medicine on an empty stomach, at least 1 hour before or 2 hours after the meal.    

Q13. How long does it take this medicine to show effect?  

Ans. The effect of this medicine can be observed in 2 to 5 hours.   

Q14. Can I take this medicine during breastfeeding?  

Ans. This medicine is not recommended in breastfeeding unless it is necessary. 

 

Interactions of Cometriq

Interactions may change how your medication works and increase the risk for side effects. Don’t forget to disclose your previous medical history with the doctor. 

Medicine interaction  

  • Ibrutinib  

  • Methadone  

  • Ritonavir  

  • Ticlopidine  

  • Warfarin  

  • Adenosine   

  • Avapritinib  

  • Dalteparin  

  • Flutamide  

Disease interaction  

  • Lung toxicity  

  • Hypertension  

  • Renal impairment  

  • Hepatic impairment  

  • Hemorrhagic events  

Alcohol interaction  

  • Interaction with alcohol is unknown. Please consult with your doctor before consuming alcohol.  

Contraindications 

  • Cometriq medicine is not recommended for use in patients with a known allergy to cabozantinib.  

  • This medicine is not recommended in patients known to be hypersensitive.  

Above Content has been reviewed by Professionals