
Ecosprin AV 75/40 mg Capsule
Salt Composition: Atorvastatin (40mg) + Aspirin (75mg)
Expiry Date: 01/2028
Inclusive of all taxes
10 Capsule
About The Product
Dual action – prevents clots, reduces stroke risk
Indication
Prevent Blood Clots
Dosage And Administration
- Ecosprin AV (75/40) mg Capsule is taken orally.
- Tablet is swallowed as it is with the help of water.
- It can be taken after or before food consumption (Prefer After Food).
- Avoid crushing, chewing, breaking or biting of tablet to maintain its efficacy.
- In general,Ecosprin AV (75/40) mg Capsule dosage in just one tablet at same time every day.
- For more personalized assistance and exact dosage, talk to your doctor about the same.
Mechanism Of Action
Ecosprin AV (75/40) mg Capsule functions in two ways: atorvastatin (40mg) competitively inhibits HMG-CoA reductase in the liver to reduce cholesterol biosynthesis, lowering LDL/triglycerides and stabilising plaques, while aspirin (75mg) irreversibly inhibits platelet COX-1 via acetylation to block thromboxane A2 synthesis and prevent aggregation/clot formation.
Faqs
Ecosprin AV (75/40) mg Capsule used to heart attacks, strokes, and cardiovascular events prescribed mainly for high-risk patients with dyslipidemia, atherosclerosis, post-heart attack/stroke prevention, angina, or peripheral artery disease.
References
• Hebert, P. R., Pfeffer, M.
A., & Hennekens, C. H.
(2002). Use of statins and aspirin to reduce risks of cardiovascular disease.
Journal of cardiovascular pharmacology and therapeutics, 7(2), 77-80. • Tippabhotla, S. K., Betha, M.
R., Gadiko, C., Battula, R., Nakkawar, M., Cheerla, R., ... & Vobalaboina, V. (2013).
Bioequivalence of fixed dose combination of atorvastatin 10 mg and aspirin 150 mg capsules: A randomized, open-label, single-dose, two-way crossover study in healthy human subjects. Drug research, 63(05), 250-257. • Farid, N.
A., Small, D. S., Payne, C.
D., Jakubowski, J. A., Brandt, J.
T., Li, Y. G., ... & Winters, K.
J. (2008).
Effect of atorvastatin on the pharmacokinetics and pharmacodynamics of prasugrel and clopidogrel in healthy subjects. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 28(12), 1483-1493. • Hirsh, J., Dalen, J.
E., Fuster, V., Harker, L. B., Patrono, C., & Roth, G.
(1995). Aspirin and other platelet-active drugs: the relationship among dose, effectiveness, and side effects.
Chest, 108(4), 247S-257S.
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