Mfd. by :- Pfizer (Fulfilled By : Magicine Pharma)
Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.
Brand Name: Palbace
Generic Name: Palbociclib
Manufacturer: Pfizer
Dosage Form: Capsule
Strength: 75mg, 100mg, and 125mg
Composition: Palbociclib
Packaging size: 21 capsules (21 / strip)
Indication: Breast cancer
Storage: Store at room temperature
Palbace (palbociclib) capsules are used in the treatment of breast cancer. This medicine belongs to a group of cancer-fighting medications called protein kinase inhibitors. It works by blocking the action of chemicals that cause cancer cells to divide and grow. It is important to take this medicine as prescribed by your doctor. Dosage is based on your medical condition and your response to the treatment. Do not take this medicine in the wrong way as it may lead to some severe side effects. Close monitoring of blood cell count is necessary while having treatment with this medicine.
Palbociclib inhibits cell growth and suppresses DNA replication in retinoblastoma tumor suppressor gene (RB) proficient cancer cells. RB cells present a significant increase in the proportion of cells in the G1 state and the presence of palbociclib produces effective dephosphorylation of RB, reduces proliferation, and induces senescence (a process by cell ages and permanently stops dividing). After the oral administration, the effect of this medicine can be observed between 6 to 12 hours.
Palbace (palbociclib) is an anti-cancer medication and it is also used to treat patients with a certain type of breast cancer that has spread to other parts of the body. Take this medicine with food and swallow the whole capsule with a glass of water. Dosage is based on your medical condition and your response to the treatment. It is advisable not to change or stop the dose without taking suggestions from your doctor. Avoid eating grapefruit or drinking grapefruit juice. Do not take the capsules that are broken.
Palbace capsules can interact with other medications. Interactions can increase the risk of side effects. Don’t forget to disclose and discuss your previous medical history with the doctor.
Atazanavir
Deferiprone
Itraconazole
Carbamazepine
Lonafarnib
Phenobarbital
Hepatic impairment
Lung toxicity
Renal impairment
Neutropenia
Interaction with alcohol is unknown. Please consult your doctor before consuming alcohol.
Do not take this medicine if you are allergic to Palbociclib.
Palbace (Palbociclib) medicine is not recommended in patients known to be hypersensitive.
This medicine may cause some mild or severe side effects. Discuss the risks and benefits of Palbace capsules with the doctor before starting the treatment.
Blurred vision
Loss of appetite
Sore throat
Bleeding gums
Difficulty in breathing
Back pain
Pale skin
Unusual tiredness
Chest pain
Red spots on the skin
Inflammation of the mouth
Fever
Rashes
Unusual weakness
Change in taste
Ulcers
Nose bleeds
Unusual bruising
Headache
Blood in urine
Chills
Rapid heart rate
Trouble in concentrating
Diarrhea
Hair loss
Nausea
Loss of strength
Decrease in white blood cell and platelets
Anemia
Infections
Vomiting
Note - Contact your medical practitioner if any side effects occur.
Take this medicine as prescribed by your doctor. Do not stop or skip your regular dosing schedule.
It is advisable not to miss a dose. If you miss a scheduled dose of Palbace capsules, contact your doctor immediately.
In case of an overdose of the Palbace capsule, the doctor will provide emergency medical treatment.
Before starting treatment with Palbace medicine, please inform your doctor about your previous medical history. If you experience any signs and symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk.
Contraception
Use suitable methods of contraception to prevent pregnancy while taking this medicine.
Children and adolescents
Palbace capsules are not advisable for use in children.
Pregnancy
Do not use this medicine if you are planning to become pregnant. Avoid this medication at the time of pregnancy.
Breastfeeding
This medicine is not recommended in breastfeeding unless it is essential. Please consult with your doctor before starting treatment with this medication.
Palbace capsules may decrease white blood cells in some patients.
Inform your doctor if you experience any side effects like - diarrhea, loss of strength, anemia, vomiting, hair loss, infections, and bleeding.
Close monitoring of blood cell counts is required while having treatment with this medication.
Avoid eating grapefruits and drinking grapefruit juice.
Do not take 2 doses of Palbace capsules at the same time.
Not safe for pregnant women.
Do not breastfeed while receiving this medication.
Do not skip your regular dosing schedule.
Do not drive or operate heavy machinery.
Do not crush or open the capsule.
Ans. It is an anti-cancer medication used in the treatment of breast cancer.
Ans. It works by blocking the action of chemicals that cause cancer cells to divide and grow.
Ans. This medicine is available in the strength of 75mg, 100mg, and 125mg.
Ans. Some common side effects are:- inflammation of the mouth, fever, rashes, pale skin, sore throat, blurred vision, etc.
Ans. It is important to take this medicine as prescribed by your doctor.
Ans. If you miss a scheduled dose of Palbace capsule, contact your doctor immediately.
Ans. This medicine is not recommended during pregnancy.
Ans. Avoid the consumption of grapefruit and grapefruit products.
Ans. Please consult your doctor before consuming alcohol.
Ans. Please consult your doctor before consuming this drug.
Ans. This medicine is not recommended in breastfeeding unless it is necessary.
Ans. This medicine may affect your vision and your ability to concentrate.
Ans. Store this medicine at room temperature.
Ans. Please consult your doctor before consuming this drug.
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