Paleno 100mg Capsule
Rx RequiredSalt Composition: Palbociclib
Expiry Date: 01/2028
Price on Request
Inclusive of all taxes
21 Capsules in Box
About The Product
Breast Cancer, Metastatic Cancer
Paleno 100mg Capsule are used in the treatment of breast cancer. Patients with certain breast cancer (human epidermal growth factor receptor 2-negative and estrogen receptor-positive) can also be treated with it.
This medicine contains an active ingredient Palbociclib that belongs to a group of cancer-fighting medications called protein kinase inhibitors. It works by blocking the action of chemicals that cause cancer cells to divide and grow.
It is used in the combination with another medicine, like fulvestrant, in patients with disease progression following endocrine therapy and an aromatase inhibitor as initial endocrine-based therapy in postmenopausal women or in men. Close monitoring of blood cell count is necessary while having treatment with this medicine.
Uses
Breast Cancer
Side Effects
The human body reacts differently to Paleno 100mg Capsule. Response or undesired symptoms vary from individual to individual. Usually, they disappear with time as the body adjusts to the medicine; these side effects don't need special medical attention. Whereas if the symptoms don't disappear with time or you have severe side effects, then consult your doctor immediately.
Some of the common side effects are mentioned below:
- Blurred vision
- Loss of appetite
- Sore throat
- Bleeding gums
- Difficulty in breathing
- Back pain
- Pale skin
- Unusual tiredness
- Chest pain
- Red spots on the skin
- Inflammation of the mouth
- Fever
- Rashes
- Change in taste
How To Use
Take the dose of Paleno 100mg as per your healthcare provider’s prescription. Do not stop taking the medicine suddenly, unless your doctor tells you. This medicine is given under the strict supervision of a doctor.
Do not self-administer. Overdose is a very unusual state for this medicine because it is given under the supervision of a healthcare provider. It can be taken without food or with food.
The doctor will provide emergency medical treatment. You should not break, crush, or chew the medicine; it should be swallowed as a whole.
How It Works
Paleno 100mg, an anticancer medicine, work by inhibiting cyclin-dependent kinase 4 and 6; as a result, cell growth ceases or stops, arresting the cancer cell cycle. Cyclin-dependent kinase 4 and 6 (chemical messengers) play an essential role in downstream signaling pathways, which lead to the proliferation of cells.
It also disrupts the cell cycle by targeting estrogen (hormone) receptor-positive breast cancer cells.
Safety Advice
FAQs
It is an anti-cancer medication used in the treatment of breast cancer.
References
- Turner, N. C., Slamon, D. J., Ro, J., Bondarenko, I., Im, S. A., Masuda, N., ... & Cristofanilli, M. (2018). Overall survival with palbociclib and fulvestrant in advanced breast cancer. New England journal of medicine, 379(20), 1926-1936.
- Wedam, S., Fashoyin-Aje, L., Bloomquist, E., Tang, S., Sridhara, R., Goldberg, K. B., ... & Beaver, J. A. (2020). FDA approval summary: palbociclib for male patients with metastatic breast cancer. Clinical Cancer Research, 26(6), 1208-1212.
- Finn, R. S., Martin, M., Rugo, H. S., Jones, S., Im, S. A., Gelmon, K., ... & Slamon, D. J. (2016). Palbociclib and letrozole in advanced breast cancer. New England journal of medicine, 375(20), 1925-1936.
- Serra, F., Lapidari, P., Quaquarini, E., Tagliaferri, B., Sottotetti, F., & Palumbo, R. (2019). Palbociclib in metastatic breast cancer: current evidence and real-life data. Drugs in context, 8, 212579.
- Cadoo, K. A., Gucalp, A., & Traina, T. A. (2014). Palbociclib: an evidence-based review of its potential in the treatment of breast cancer. Breast Cancer: Targets and Therapy, 123-133.
- Turner, N. C., Ro, J., André, F., Loi, S., Verma, S., Iwata, H., ... & Cristofanilli, M. (2015). Palbociclib in hormone-receptor–positive advanced breast cancer. New England Journal of Medicine, 373(3), 209-219.
Medical Disclaimer
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The content on this website has been produced solely for informational purposes. This is not intended to take the place of medical advice and care provided by a licensed professional, though.
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