Sugistran 25mg capsule

• Renal cell carcinoma (RCC)
• Gastrointestinal stromal tumors (GIST)
• Pancreatic neuroendocrine tumors (PNET)
• Medullary thyroid cancer
• Certain kidney cancer

Like other anticancer medicines, Sugistran 25mg Capsule also has some common to severe side effects. These undesired symptoms observed in the body after taking this medicine and usually disappear with time as the body adjusts to the medicine.

Common Side Effects Include:

• Decreased appetite
• Mucositis
• High blood pressure
• Hand-foot syndrome
• Bleeding disorder
• Taste change
• Nausea
• Vomiting
• Weakness
• Fatigue
• Diarrhea

Above mentioned effects don't need any special medical attention, but if you observe them continually, talk to your doctor immediately.

• The recommended dose Sugistran 25mg Capsule may vary according to the type & stage of cancer, or age, weight, and other health factors of the patients. This capsule should be swallowed as a whole with water and do not crush, chew, or open it.
• It is usually taken once a day, with or without food, at a fixed time each day. Don't miss a dose or double the dose to compensate for the missed dose.
  
  

• Sugistran 25mg Capsule is an anticancer medicine with active ingredient Sunitinib that works by blocking the action of specific proteins known as tyrosine kinases.
• As this protein helps in signaling pathways that control growth and multiplication of cells. Thereby it effectively controls the progression of cancer, especially in the advance stages of cancer.
  
  

• Motzer, R. J., Rini, B. I., Bukowski, R. M., Curti, B. D., George, D. J., Hudes, G. R., ... & Michaelson, M. D. (2006). Sunitinib in patients with metastatic renal cell carcinoma. Jama, 295(21), 2516-2524. https://pubmed.ncbi.nlm.nih.gov/16757724/
• Kelleher, F. C., & McDermott, R. (2008). Response to sunitinib in medullary thyroid cancer. Annals of internal medicine, 148(7), 567. https://pubmed.ncbi.nlm.nih.gov/18378960/
• Raymond, E., Hammel, P., Dreyer, C., Maatescu, C., Hentic, O., Ruszniewski, P., & Faivre, S. (2012). Sunitinib in pancreatic neuroendocrine tumors. Targeted oncology, 7(2), 117-125. https://pubmed.ncbi.nlm.nih.gov/22661319/
• Gan, H. K., Seruga, B., & Knox, J. J. (2009). Sunitinib in solid tumors. Expert opinion on investigational drugs, 18(6), 821-834. https://pubmed.ncbi.nlm.nih.gov/19453268/
• Motzer, R. J., Rini, B. I., Bukowski, R. M., Curti, B. D., George, D. J., Hudes, G. R., ... & Michaelson, M. D. (2006). Sunitinib in patients with metastatic renal cell carcinoma. Jama, 295(21), 2516-2524. https://pubmed.ncbi.nlm.nih.gov/16757724/
• Hiles, J. J., & Kolesar, J. M. (2008). Role of sunitinib and sorafenib in the treatment of metastatic renal cell carcinoma. American journal of health-system pharmacy, 65(2), 123-131. https://pubmed.ncbi.nlm.nih.gov/18192256/
• Hopkins, T. G., Marples, M., & Stark, D. (2008). Sunitinib in the management of gastrointestinal stromal tumours (GISTs). European Journal of Surgical Oncology (EJSO), 34(8), 844-850. https://www.researchgate.net/publication/5766997_Sunitinib_in_the_management_of_gastrointestinal_stromal_tumors_GISTs