Sunicine 12.5mg Capsule

Sunicine 12.5mg Capsule

Prescription requiredRx Required

Salt Composition: Sunitinib

Expiry Date: 01/2028

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28 Capsules in Bottle

About The Product

Kidney Cancer,  Gastrointestinal stromal tumors

Sunicine 12.5mg Capsule is an anticancer drug consisting of an active ingredient called Sunitinib. The doctor prescribes this medication to those who are diagnosed with early-stage Gastrointestinal Stromal Tumor (GIST), Advanced Renal Cell Carcinoma (RCC), and Pancreatic Neuroendocrine Tumors. This drug can only be used as a first-line treatment option for people who are diagnosed with early-stage cancer and cancer that can't be removed by surgery. This capsule restricts the function of specific enzymes that promote the growth of tumor cells. Eventually, it slows down the progression of cancer cells. Sunicine capsule is considered to be an unsafe drug for people under the age of 18.

Uses

  • Gastrointestinal stromal tumor
  • Renal cell carcinoma
  • Pancreatic neuroendocrine tumor

Side Effects

Side effects of Sunicine 12.5mg capsule may occur because the formulations are new to your body's mechanisms. These are manageable and don't require medical attention.

Common side effects include:

  • Diarrhea
  • Fever
  • Nervousness and dizziness
  • Headache
  • Fatigue
  • Difficulty in urination
  • Difficulty in breathing
  • Unusual weight loss
  • Irregular heartbeat
  • Coughing up blood
  • Chest tightness
  • Difficulty in urination
  • Rare side effects:
  • Seizures
  • Abdominal pain
  • Skin rash and darkening
  • Changes in vision
  • Numbness in the leg
  • Decreased white blood cell count (neutrophils)
  • Blistering of the skin
  • Joint stiffness
  • Inform your doctor immediately if you experience any persistent or unusual side effects.

How To Use

  • The dosage and treatment duration with Sunicine 12.5mg Capsule are determined by the doctor as per the stage & type of cancer and the overall patient's health.
  • Swallow the tablet as a whole with water and don't chew, crush, or break it.
  • This tablet can be taken with or without food.
  • Don't miss a dose or overdose on the medicine.

How It Works

Sunicine 12.5mg Capsule contains Sunitinib that belongs to the class of protein kinase inhibitors. It works by targeting and blocking the activity of tyrosine kinase receptors, which are responsible for the growth and multiplication of cancerous cells.

In this way, it reduces the uncontrolled growth of cancer cells and controls the tumor's size. It also prevents the formation of blood vessels in tumors.

Safety Advice

Alcohol

Avoid the consumption of alcohol while taking Sunicine 12.5mg Capsule, as alcohol can reduce the effectiveness of the medicine and worsen the symptoms

Pregnancy

Do not take Sunicine 12.5mg Capsule without consulting the doctor in case of pregnancy, as it is an unsafe medicine during this period.

Breast Feeding

Sunicine 12.5mg Capsule is unsafe to use during breastfeeding as it may cause toxicity to the baby.

Driving

Sunicine 12.5mg Capsule may cause side effects such as dizziness or lack of concentration, which could affect your ability to drive. So it's better to avoid driving or operating heavy machinery.

Kidney

Sunicine 12.5mg Capsule is safe for use in kidney disease if prescribed by the doctor. No dosage adjustment is necessary for this Tablet.

Liver

Sunicine 12.5mg Capsule is safe for use in liver disease if prescribed by the doctor. No dosage adjustment is necessary for this Tablet.

Missed Doses

  • It is advised not to miss any scheduled dosage of Sunicine 12.5mg Capsule.
  • In case you miss a dose, consult your doctor immediately.
  • Don't overdose to compensate for the missed one.
  • Contact your doctor or any healthcare provider and seek medical attention immediately in such cases.

Quick Tips

  • Must avoid consumption of grapefruits in any form as they may interact with Sunicine Capsules.
  • Take Sunicine 12.5mg Capsule preferably at the same time regularly for better results.
  • Drink plenty of water and fluids to avoid dehydration.
  • Taking Sunicine 12.5mg can cause diarrhea.
  • If you're suffering from a bleeding problem, share it with your doctor before taking Sunicine 12.5mg Capsule.
  • Monitor your blood sugar & blood pressure and thyroid hormone levels on a regular basis.
  • Taking Sunicine Capsule can affect these.
  • Don't take this medicine if you're pregnant, breastfeeding, or planning to be pregnant.
  • It is advisable to use effective methods of birth control and contraceptive pills to avoid pregnancy while under treatment with Sunicine 12.5mg Capsule.

FAQs

Sunicine 12.5mg Capsule is given to cure patients diagnosed with Gastrointestinal Stromal Tumor (GIST), Advanced Renal Cell Carcinoma (RCC), and Pancreatic Neuroendocrine Tumors.


Reference

  1. Minor, D. R., Kashani-Sabet, M., Garrido, M., O'Day, S. J., Hamid, O., & Bastian, B. C. (2012). Sunitinib therapy for melanoma patients with KIT mutations. Clinical cancer research, 18(5), 1457-1463 - https://pubmed.ncbi.nlm.nih.gov/22261812/
  2. Ravaud, A., Motzer, R. J., Pandha, H. S., George, D. J., Pantuck, A. J., Patel, A., ... & Patard, J. J. (2016). Adjuvant sunitinib in high-risk renal-cell carcinoma after nephrectomy. New england journal of medicine, 375(23), 2246-2254 - https://pubmed.ncbi.nlm.nih.gov/27718781/
  3. Gan, H. K., Seruga, B., & Knox, J. J. (2009). Sunitinib in solid tumors. Expert opinion on investigational drugs, 18(6), 821-834 - https://pubmed.ncbi.nlm.nih.gov/19453268/
  4. Motzer, R. J., Rini, B. I., Bukowski, R. M., Curti, B. D., George, D. J., Hudes, G. R., ... & Michaelson, M. D. (2006). Sunitinib in patients with metastatic renal cell carcinoma. Jama, 295(21), 2516-2524 - https://pubmed.ncbi.nlm.nih.gov/16757724/
  5. Faivre, S., Demetri, G., Sargent, W., & Raymond, E. (2007). Molecular basis for sunitinib efficacy and future clinical development. Nature reviews Drug discovery, 6(9), 734-745 - https://pubmed.ncbi.nlm.nih.gov/17690708/
  6. Rini, B. I. (2007). Sunitinib. Expert opinion on pharmacotherapy, 8(14), 2359-2369.

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