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TS-ONE

TS-ONE

Prescription requiredRx Required

Salt Composition: Tegafur, Gimeracil, Oteracil Potassium

Expiry Date: 01/2028

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56 capsule

About The Product

Gastric Cancer

​TS-ONE Capsule is an anti-cancer medicine used in the treatment of Gastric Cancer with other medications like Cisplatin. It is also used in the treatment of head and neck cancer, lung, biliary tract, breast, pancreatic, and colorectal cancer. TS-ONE capsules comprise three agents namely tegafur (FT), gimeracil (CDHP), and oteracil potassium (Oxo).​

Description

​ The antitumor activity of TS-ONE after its administration (orally) is based on 5-fluorouracil (5-FU) which tends to appear gradually in the body via the transformation of FT. CDHP increased the 5-FU’s concentration, which is converted from FT, by selectively and reversibly inhibiting DPD, a catabolic enzyme of 5-FU, which is particularly distributed in the liver.

5-fluoronucleotides, phosphorylated metabolites of 5-FU, are highly maintained in tumor tissues, thereby enhancing the antitumor activity in proportion to the increase in the concentration of 5-FU in the body. Oxo works to selectively inhibit the production of 5-fluoronucleotides from 5-FU by enabling the distribution in the gastrointestinal tissue as a result of the medicine’s administration and selectively inhibiting orotate phosphoribosyltransferase. ​

Side Effects

​TS-ONE Capsules may cause certain side effects. Some of the common and serious side effects are stated below. Make sure to contact your healthcare professional if side effects occur after administration or last longer than usual.​

Fever 

Headache 

Chills 

Nausea 

Sore throat 

Malaise 

Dehydration

Diarrhea 

Abdominal pain

Speech disorder

Sensory disturbance 

Tiredness 

Lack of energy 

Vomiting 

Irregular heartbeat 

Unusual bleeding 

How To Use

  • ​ The doctor will recommend the dose strength and frequency of your dose as per your health condition and the body’s tolerance.
  • Take the capsule as a whole with water.
  • Do not crush or cut it. ​

Safety Advice

Alcohol
It is advisable not to consume alcohol while taking medicine.
Pregnancy
Do not take ​TS-ONE Capsules without consulting the doctor, in case of pregnancy.
Breast Feeding
Without a doctor's consultation, do not take this medicine if you're breastfeeding.
Driving
It is advisable not to drive or operate heavy machinery, you may feel dizzy as one of the side effects of the medicine.
Kidney
Do not take ​TS-ONE Capsules without a doctor's consultation in case of kidney problems.
Liver
Share your medical history with the doctor in case of liver disease before taking this medicine.

Missed Doses

  • If you forget to take a dose of TS-ONE Capsules , consult your doctor.
  • Don’t double up the next dose to cope with the missed one unless your doctor recommends it. ​

FAQs

​ TS-ONE is used in the treatment of Gastric Cancer with other medications like Cisplatin.

It is also used in the treatment of head and neck cancer, lung, biliary tract, breast, pancreatic, and colorectal cancer. ​

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