How will Adflu 50mg Injection be given to cancer patients?

Adflu 50mg Injection is a prescription-based anticancer drug. This medicine should be given intravenously by an experienced nurse or doctor. Please do not self-administer.

What precautions should I take during the treatment of Adflu 50mg Injection?

Avoid exposure to the sun and infections, report if you observe any unusual symptoms, and share your medical history with your healthcare expert, especially if you have autoimmune conditions, are pregnant, are planning to be pregnant, or are breastfeeding.

Can I drink alcohol while taking the Adflu 50mg Injection?

It is advised not to take alcohol while taking the Adflu 50mg Injection, because consuming alcohol can cause serious side effects and can damage your liver badly. Consult your doctor if you have concerns or queries.

I forgot to take the Adflu 50mg Injection. What to do?

As soon as you remember, take the missed dose. unless it's time for your next dose. You should never take a double dose to make up for a missed one.

What are the side effects of Adflu 50mg Injection?

Common side effects of Adflu 50mg Injection are constipation, muscle pain, swelling, nausea, diarrhea, infection, loss of appetite, hair loss, vomiting, and weakness.

How does Adflu 50mg Injection work?

Adflu 50mg Injection cross-links with the DNA, and it damages the DNA (genetic material) present in the cancer cells. It prevents the cancer cells from synthesizing or copying their genetic material, hence stopping the growth and division of cancer cells.

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Adflu 50mg Injection

Salt Composition: Fludarabine Phosphate

Expiry Date: 01/2028

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About The Product

Chronic Lymphocytic Leukemia

Adflu 50mg Injection is a medication that contains the active ingredient fludarabine. It is a chemotherapy medicine. It is used to treat B-cell chronic lymphocytic leukemia (CLL). it is a condition when the body produces many abnormal white blood cells and lymph nodes that spread and start to grow in different parts of the body. It leads to a decrease in red blood cells, organ failure, and severe bleeding and infections.

Side Effects

Undesired symptoms or responses vary from person to person as the human body reacts differently to the Admatrone 250mg Tablet, but they typically resolve naturally within a few days as the body adjusts to the medicine, requiring no medical attention.
In case these symptoms don't go away and you face severe side effects, then immediately consult your doctor or medical team.
Some of the common side effects of the Admatrone 250mg Tablet are: Fatigue Headache, Fever High blood pressure Rash Indigestion Nausea diarrhea, or constipation Loss of appetite Low blood count, Hair loss,

How To Use

If a person has a history of renal, liver, cardiovascular illness, hypoglycemia, or fluid retention, they should avoid taking Admatrone 250mg Tablet.
It should be taken two hours before or after meals on an empty stomach.
It is not advised for women or children to use Admatrone.
Admatrone 250mg Tablet can interact with other medications; therefore, it's best to let your doctor know before taking any other medications.
When treating prostate cancer, this medication is frequently used with prednisolone.
The medication should not be broken, crushed, or chewed.

How It Works

Adflu 50mg Injection is given slowly in the veins; it is generally advised to receive lots of water before and after the injection to protect the kidneys. Do not use the same injection or syringe for another injection, as there is a chance of interaction.

Always check the vial of injection before using it for discoloration or any kind of particulate matter, and shake well for uniform mixing of the product. Adflu 50mg Injection is administered once every 3-4 weeks or for 5 consecutive days.

Always consult your doctor before taking the vaccine, especially if you have a family history of blood disorders, heart problems, lung problems, pain in the limbs, or kidney problems.

Safety Advice

Alcohol

Excessive alcohol consumption can decrease the immunity of the individual and weaken the liver function. However, moderate levels of alcohol do not interfere with the working of the Adflu 50mg Injection, as per the research.

Pregnancy

The Adflu 50mg Injection should be injected after consulting the doctor; during pregnancy, it is not suggested to take it routinely. The Adflu 50mg Injection can be injected in case of severe, life-threatening conditions. However, it may harm the unborn.

Breast Feeding

The Adflu 50mg Injection is considered unsafe to be taken while breastfeeding, as there is a chance that it may pass to the developing baby through the breast milk of the mother. It is generally considered unsafe, and there is no clear evidence found in the clinical data that how it harms the baby.

Driving

Driving after taking the Adflu 50mg Injection does not affect or interfere with driving ability or disturb while operating machinery. However, if you get a fever or dizziness after the injection, avoid driving until you feel better.

Kidney

The Adflu 50mg Injection is considered unsafe for people with kidney problems. It contains Fludarabine, which can damage the kidneys.

Liver

The Adflu 50mg Injection is generally considered beneficial and safe for people with mild to moderate liver disease. Dose should be adjusted, take it with caution.

FAQs

During pregnancy, it is not safe to take Adflu 50mg Injection, as it can cause harm to the unborn baby. Also, during breastfeeding, this medicine must not be used.

Please make sure to consult your healthcare provider regarding the same.

Reference

Alas, S., Emmanouilides, C., & Bonavida, B. (2023).

Inhibition of interleukin 10 by rituximab results in down-regulation of Bcl-2 and sensitization of B-cell non-Hodgkin’s lymphoma to apoptosis. Clinical cancer research, 7(3), 709-723.

Catovsky D, Richards S, Matutes E, Oscier D, Dyer M, Bezares RF, Pettitt AR, Hamblin T, Milligan DW, Child JA, Hamilton MS, Dearden CE, Smith AG, Bosanquet AG, Davis Z, Brito-Babapulle V, Else M, Wade R, Hillmen P; UK National Cancer Research Institute (NCRI) Haematological Oncology Clinical Studies Group; NCRI Chronic Lymphocytic Leukaemia Working Group.

Assessment of fludarabine plus cyclophosphamide for patients with chronic lymphocytic leukaemia (the LRF CLL4 Trial): a randomised controlled trial. Lancet.

2007 Jul 21;370(9583):230-239. Keating, M.

J. (2020).

Fludarabine phosphate in the treatment of chronic lymphocytic leukemia. In Seminars in Oncology (Vol.

17, No. 5 Suppl 8, pp.

49-62). Puccio, C.

A., Mittelman, A., Lichtman, S. M., Silver, R.

T., Budman, D. R., Ahmed, T., & Arlin, Z.

A. (2024).

A loading dose/continuous infusion schedule of fludarabine phosphate in chronic lymphocytic leukemia. Journal of Clinical Oncology, 9(9), 1562-1569.

Tam, C. S., O'Brien, S., Wierda, W., Kantarjian, H., Wen, S., Do, K.

A., & Keating, M. J.

(2025). Long-term results of the fludarabine, cyclophosphamide, and rituximab regimen as initial therapy of chronic lymphocytic leukemia.

Blood, The Journal of the American Society of Hematology, 112(4), 975-980.

Last updated: 5 Aug 2026 | 04:33 PM (IST)

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