
Avastin 400mg injection
Salt Composition: Bevacizumab
Expiry Date: 01/2028
Inclusive of all taxes
1 Vial
About The Product
Colorectal cancer
Avastin 400mg injection belongs to the category of anticancer medicines. This medicine is primarily used to treat patients diagnosed with breast cancer, brain cancer, cervical cancer, kidney cancer, lung cancer, ovarian cancer, and colorectal cancer. The growth of cancer cells is uncontrollable and abnormal in the human body. It is difficult to diagnose cancer in the early stages.
When diagnosed in advanced stages, only the symptoms of the disease can be reduced. Avastin injection is typically administered in combination with another anticancer medication as part of a combination therapy to enhance the treatment's efficacy. It is given as an infusion, which means it is given into the veins through a small needle or port (device placed under your skin).
Uses
- Cancer of the colon and rectum
- Ovarian cancer
- Cervical cancer
- Kidney cancer
- Brain tumor
- Non-small cell lung cancer
Side Effects
The human body shows undesired symptoms after taking the Avastin 400mg injection. Usually, they disappear with time as the body adjusts to the medicine. These side effects don't need special medical attention. It is advised to consult your doctor if these symptoms become unmanageable.
Some of the common side effects of Avastin injection are mentioned below:
- Fever
- Fatigue
- Back pain
- Headache
- Mouth sore
- Weight loss
- Constipation
- Nose bleeding
- Breathlessness
- Taste alteration of appetite
- Abdominal pain, increased heart rate
- High blood pressure
- Nausea and vomiting
- Numbness in hands and feet. Severe side effects:
- Gut infection
- Blood clotting
- Hemorrhage
- Protein in urine
- Decrease in the level of white blood cells
How To Use
- Avastin 400mg injection is a prescription-based anticancer drug.
- It is advised to take this injection after consulting your healthcare expert.
- This medicine should be given intravenously by an experienced nurse or doctor. Please do not self-administer.
How It Works
- An anti-angiogenic medication, Avastin 400mg injection, works by blocking vascular endothelial growth factor (VEGF), which is a protein.
- It basically functions by cutting the oxygen supply and nutrients to cancerous cells by stopping the formation of blood vessels that supply them.
Safety Advice
The interaction of alcohol with this drug is still unknown. It is advisable not to consume alcohol while taking Avastin 400mg injection. It is advised to consult your doctor for further information.
Avastin 400mg injection may be considered unsafe during pregnancy. Please consult your doctor in such condition.
Avastin 400mg injection is probably not safe if you're breastfeeding. Kindly consult your doctor.
It is advisable not to drive or operate heavy machinery as you may feel dizzy after taking Avastin 400mg injection.
Share your medical history with your healthcare expert in case of kidney disease before taking Avastin 400mg injection.
Inform your doctor before starting Avastin 400mg injection if you have liver disease to avoid any serious side effects.
Missed Doses
- It is advised not to miss any scheduled dosage of Avastin 400mg injection.
- In case you miss a dose, consult your doctor immediately.
- Don't overdose to compensate for the missed one.
- Contact your doctor or any healthcare provider and seek medical attention immediately in such cases.
Quick Tips
It is advised to use effective birth control methods and avoid pregnancy during the treatment with Avastin.
A person should avoid smoking while undergoing treatment with Avastin injection. Smoking may reduce the effectiveness of medicine.
Monitor your blood sugar & pressure, Kidney & Liver function (KFT & LFT), Heart function at proper intervals after taking Avastin 400mg injection
Swelling of hands, lips, and weight gain are some of the side effects observed after taking Avastin. To reduce them, the doctor may suggest some medication.
Skin becomes extremely sensitive after taking the Avastin injection. It is advised to cover your skin exposed to direct sun rays and use high SPF sunscreen before going out.
It is advised to avoid taking analgesics/ antacids (medicines used to neutralize the stomach acid) while taking Avastin 400mg injection, as it may reduce the effectiveness of the medicine.
Keep your body hydrated as Diarrhea is one of the common side effects experienced after taking Avastin 400mg injection. Consult your doctor if it doesn't stop or if blood appears in your stools.
In case you notice symptoms like blurred vision, difficulty breathing, cough & fever, and diarrhea while taking Avastin injection, consult your doctor immediately before these symptoms become severe.
Taking Avastin 400mg injection can lower your ability to heal wounds rapidly. So avoid doing such activities that can lead to bruising and wounds. Inform your doctor if you are going an emergency surgical procedure.
If you experience any kind of symptoms after taking Avastin 400mg injection like unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever), or other signs of infection, it is important to Inform your doctor as soon as possible.
FAQs
Avastin injection can pass through the mother's blood and harm the unborn baby.
So, it is advised not to give this drug to pregnant and breastfeeding women.
Reference
- Bakri SJ, Snyder MR, Reid JM, Pulido JS, Singh RJ. (2023). Pharmacokinetics of intravitreal bevacizumab (Avastin). Ophthalmology. 114(5):855-9 - https://pubmed.ncbi.nlm.nih.gov/17467524/
- Bakri SJ, Snyder MR, Reid JM, Pulido JS, Ezzat MK, Singh RJ. (2024). Pharmacokinetics of intravitreal ranibizumab (Lucentis). Ophthalmology. 114(12):2179-82 - https://pubmed.ncbi.nlm.nih.gov/18054637/
- Oguchi Y, Sekiryu T, Omori T, Kato Y, Ogasawara M, Sugano Y, Itagaki K, Ojima A, Machida T, Sekine H. (2025). Anaphylatoxin concentration in aqueous and vitreous humor in the eyes with vitreoretinal interface abnormalities. Exp Eye Res;195:108025 - https://pubmed.ncbi.nlm.nih.gov/32224205/
- Emerson MV, Lauer AK, Flaxel CJ, Wilson DJ, Francis PJ, Stout JT, Emerson GG, Schlesinger TK, Nolte SK, Klein ML. (2023). Intravitreal bevacizumab (Avastin) treatment of neovascular age-related macular degeneration. Retina 27(4):439-44 - https://pubmed.ncbi.nlm.nih.gov/17420695/
- Kumar A, Sinha S. (2025). Intravitreal bevacizumab (Avastin) treatment of diffuse diabetic macular edema in an Indian population. Indian J Ophthalmol. 55(6):451-5 - https://pubmed.ncbi.nlm.nih.gov/17951903/
- Kandasamy R, Constantinou M, Rogers SL, Sandhu SS, Wickremasinghe S, Al-Qureshi S, Lim LL. (2024). Prospective randomised clinical trial of intravitreal bevacizumab versus triamcinolone in eyes with diabetic macular oedema undergoing cataract surgery: 6-month results. Br J Ophthalmol. 103(12):1753-1758.
- Taira K, Okazaki S, Akiyoshi K, Machida H, Ikeya T, Kimura A, Nakata A, Nadatani Y, Ohminami M, Fukunaga S, Otani K, Hosomi S, Tanaka F, Kamata N, Nagami Y, Fujiwara Y. (2023). Short bevacizumab infusion is an effective and safe treatment for colorectal cancer. Mol Clin Oncol. 17(3):139.
- Perdrizet K, Leighl NB. (2024). The Role of Angiogenesis Inhibitors in the Era of Immune Checkpoint Inhibitors and Targeted Therapy in Metastatic Non-Small Cell Lung Cancer. Curr Treat Options Oncol. 18;20(3):21
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