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Azatirel 100mg Injection

Azatirel 100mg Injection

Prescription requiredRx Required

Salt Composition: Azacitidine

Expiry Date: 01/2028

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1 vial(s)

About The Product

Chemotherapy drug., Bone Marrow Cancer



Description

Azatirel 100mg Injection is a chemotherapy drug which involves in the treatment of bone marrow cancer. The medication active ingredient is Azacitidine which works by stopping the production of cancer cells and preventing from multiplication of tumor cells in the body.

The medication belongs to the class of anti-metabolites which interfere with the with DNA or RNA synthesis, thereby slowing the growth of rapidly dividing malignant cells. A doctor's prescription is strictly required before using the medication, as the injection is not prescribed for the adult child under the age of 18.

Indication

Bone marrow cancer

Common Side Effects

  • Some patients experience various symptoms which resolve on their own but some may require proper medical attention.
  • Some of the side effects of Azatirel 100mg Injection are: ● Injection site reaction (pain, swelling or redness) ● Nausea ● Vomiting ● Weakness ● fever ● Chills ● Diarrhea ● Constipation ● Bruise

Dosage And Duration

  • Azatirel 100mg Injection is an anti-cancer medication.
  • Doctor recommended taking the injection with or without food at the fixed time.
  • The injection is given once daily and after some time cycle repeats every few weeks.
  • Total duration may involve multiple duration over months, depending on the response.
  • The exact dose and number of days in each cycle are determined only by the oncologist.
  • Do not self administer this medication under any circumstances.

Mechanism Of Action

Bone marrow cancer disrupts the production of healthy cells and weakens the immune system that decreases the body's ability to fight with the infection. Azatirel tablet is a nucleoside metabolic inhibitor which works by inhibiting the cancer cells in DNA and prevent the body from multiplication of cancer cells.

The medicine kills abnormal cells while allowing normal cells to recover by improving overall bone marrow function.

Safety Advice

Alcohol
Alcohol is prohibited while using Azatirel 100mg Injection as it interrupt with the treatment. Consult the doctor fore more safety precautions.
Driving
Azatirel 100mg injection do not cause dizziness however consult with the healthcare provider if you experience any harmful symptoms.
Pregnancy
Pregnant women should discuss with the doctor if she have to take Azatirel 100mg Injection on pregnancy for safe and effective treatment option.
Kidney
Azatirel 100mg should be considered safe for kidney patient only under strict medical supervision. Dose adjustment must be needed. Please consult the doctor.
Liver
Liver patient should discuss with the doctor before using Azatirel 100mg Injection as the medicine can disturb the liver function.

Reference

• Issa, J. P.

J., Kantarjian, H. M., & Kirkpatrick, P.

(2005). Azacitidine.

Nature Reviews Drug Discovery, 4(4), 275-276. • Kaminskas, E., Farrell, A. T., Wang, Y.

C., Sridhara, R., & Pazdur, R. (2005).

FDA drug approval summary: azacitidine (5-azacytidine, Vidaza™) for injectable suspension. The oncologist, 10(3), 176-182. • Glover, A.

B., & Leyland-Jones, B. (1987).

Biochemistry of Azacitidine: A Review¹. Cancer treatment reports, 71(10-12), 959. • DiNardo, C.

D., Jonas, B. A., Pullarkat, V., Thirman, M.

J., Garcia, J. S., Wei, A.

H., ... & Pratz, K. W.

(2020). Azacitidine and venetoclax in previously untreated acute myeloid leukemia.

New England journal of medicine, 383(7), 617-629. • Kaminskas, E., Farrell, A., Abraham, S., Baird, A., Hsieh, L. S., Lee, S.

L., ... & Pazdur, R. (2005).

Approval summary: azacitidine for treatment of myelodysplastic syndrome subtypes. Clinical cancer research, 11(10), 3604-3608.

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