Bortezomib 2mg Injection

Bortezomib 2mg Injection

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Salt Composition: Bortezomib

Expiry Date: 01/2028

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About The Product

Blood Cancer

Bortezomib 2mg Injection is an anticancer medicine that is the first potent therapeutic proteasome inhibitor. This medicine is primarily prescribed to treat multiple myeloma and mantle-cell lymphoma. It works by slowing down or stopping the growth of cancer cells. This Injection is usually given in combination with another anticancer medicine as a part of combination therapy to increase the efficacy of the treatment.

Side Effects

  • Like any other anticancer medicine, Bortezomib 2mg Injection also shows some side effects, which vary from one person to another according to various health factors.
  • Most of them are mild, and some are serious enough to need immediate medical attention.
  • Some Common side effects include: Fever Anxiety Diarrhea Hair loss Pneumonia Mouth ulcer Dehydration Constipation Muscle Cramps Loss of Appetite Difficulty sleeping Stomach infection Irregular heart rate Nausea and vomiting Difficulty in breathing Weakness & Dizziness Low Blood Cell Counts Some Severe side effects: Swelling in feet Kidney dysfunction High blood pressure Heart rate fluctuation Severe skin Inflammation Contact the doctor immediately in case of any unusual or persistent side effects.

How To Use

  • Bortecine 2mg Injection is a prescription-based anticancer drug.
  • Dosage and duration of treatment are usually decided by the doctor according to the patient's health condition, type & stage of cancer, etc.
  • It is advised to take this injection after consulting your healthcare expert.
  • This medicine should be given intravenously by an experienced nurse or doctor.
  • Please do not self-administer.

How It Works

Bortezomib 2mg Injection is an anticancer medicine that belongs to the drug class of proteasome inhibitors. This medicine acts by causing toxicity in cancer cells.

It inhibits the action of the 26S proteasome and blocks a key cellular signaling pathway. This interference with the signaling pathway transforms the cancer cells into being sensitive to chemotherapy.

It reduces the degradation of proteins within cells. Through which, this drug promotes the deposition of a specific protein while reducing the growth and proliferation of cancer cells.

Safety Advice

Alcohol
The interaction of alcohol with this drug is still unknown. It is advisable not to consume alcohol while taking Bortezomib 2mg Injection.
Pregnancy
Bortezomib 2mg Injection is not recommended during pregnancy as it is unsafe for the developing fetus. Doctors rarely prescribe this medicine in pregnancy.
Breast Feeding
Bortezomib 2mg Injection is unsafe to use during breastfeeding as it may cause toxicity to the baby.
Driving
Bortezomib 2mg Injection may cause side effects such as dizziness or lack of concentration, which could affect your ability to drive. So it's better to avoid driving or operating heavy machinery.
Kidney
Consumption of Bortezomib 2mg Injection should be avoided without informing the doctor if you have any kidney-related issues. It is safe if prescribed.
Liver
Consumption of Bortezomib 2mg Injection should be avoided without informing the doctor if you have any liver-related issues. It is safe if prescribed.

Missed Doses

  • It is advised not to miss any scheduled dosage of Bortecine 2mg Injection.
  • In case you miss a dose, consult your doctor immediately.
  • Don't overdose to compensate for the missed one.
  • Contact your doctor or any healthcare provider and seek medical attention immediately in such cases.

Quick Tips

It is advised to use effective birth control ways and avoid pregnancy during the treatment with Bortecine 2mg Injection.


A person should avoid smoking while undergoing treatment with Bortecine. Smoking may reduce the effectiveness of medicine.


Skin becomes extremely sensitive after taking Bortecine 2mg Injection. It is advised to cover your skin exposed to direct sun rays and use high SPF sunscreen before going out.


Swelling of hands, lips, and weight gain are some of the side effects observed after taking Bortecine 2mg Injection. To reduce them, the doctor may suggest some medication.


It is advised to avoid taking analgesics/ antacids (medicines used to neutralize the stomach acid) while taking Bortecine 2mg Injection, as it may reduce the effectiveness of the medicine.


Keep your body hydrated as Diarrhea is one of the common side effects experienced after taking Bortecine 2mg Injection. Consult your doctor if it doesn't stop or if blood appears in your stools.


Monitor your blood sugar & pressure, Kidney & Liver function (KFT & LFT), Heart function, cholesterol level and bone mineral density (BMD) at proper intervals after taking Bortecine 2mg Injection.


In case you notice symptoms like blurred vision, difficulty breathing, cough & fever, and diarrhea while taking Bortecine 2mg Injection, consult your doctor immediately before these symptoms become severe.


If you experience any kind of symptoms after taking Bortecine 2mg Injection, like unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever), or other signs of infection, it is important to Inform your doctor as soon as possible.

FAQs

Bortecine 2mg Injection is not recommended for use during pregnancy because this medicine can pass from mother to baby via blood and may cause birth defects.


Reference

1.https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/215331s000lbl.pdf

2.https://www.ncbi.nlm.nih.gov/books/NBK519559/

3.https://medlineplus.gov/druginfo/meds/a607007.html

4. Romano, A., Chiarenza, A., Consoli, U., Conticello, C., Forte, S., Uccello, G., ... & Di Raimondo, F. (2013). Intravenous injection of bortezomib, melphalan, and dexamethasone in refractory and relapsed multiple myeloma. Annals of oncology, 24(4), 1038-1044.

5.Wu, S., Zheng, C., Chen, S., Cai, X., Shi, Y., Lin, B., & Chen, Y. (2015). Subcutaneous administration of bortezomib in combination with thalidomide and dexamethasone for treatment of newly diagnosed multiple myeloma patients. BioMed research international, 2015(1), 927105.


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