Carfilnat 60mg Injection
Prescription Required
Manufactured By
Pack of
1 Injection
Salt Composition
Carfilzomib
Storage
Keep in cold place
All Substitutes
Overview
Carfilnat 60mg Injection belongs to the category of anticancer medicines. It is primarily used to treat patients diagnosed with Multiple myeloma and Mantle-cell lymphoma. The active ingredient of the Carfilnat is Carfilzomib, which belongs to the drug class of Proteasome Inhibitors. It is administered as an injection by an experienced nurse or medical professional. This Injection works by killing the cancer cells and reducing the size of the tumor. This Injection is usually given in combination with another anticancer medicine as a part of combination therapy to increase the efficacy of the treatment.
Indication
Bone marrow Cancer, Multiple Myeloma, Preventing tumor growth, Preventing tumor growth
Side Effects
Every medicine has some side effects that typically manage on their own as your body gets used to the medicine, but some people may experience severe side effects rarely. In that case, the patient should contact the doctor immediately.
Some common side effects of Carfilnat 60mg Injection include:
Fever
Cough
Fatigue
Diarrhea
Headache
Breathlessness
Skin inflammation
Nausea & vomiting
Back and muscle pain
Low levels of RBCs & platelets in the blood
Contact your healthcare provider if you face any unusual or persistent side effects.
How To Use
Cisplat 10mg Injection is given intravenously by a doctor or trained nurse under strict medical supervision. It is not self-administrable. The dosage and duration of the treatment are determined by the doctor based on the stage & type of cancer and the patient's health condition.
How It Works
Carfilnat 60mg Injection is an anticancer medication that belongs to the class of drugs known as Proteasome Inhibitors. This medication works by blocking proteasomes, which are enzymes responsible for breaking down proteins in cells. By inhibiting this process, Carfilnat prevents the growth and multiplication of cancer cells, ultimately leading to their death.
Safety Advice
Alcohol
consult your doctor
Avoid the consumption of alcohol while taking Carfilnat 60mg Injection, as alcohol can reduce the effectiveness of the medicine and worsen the symptoms
Pregnancy
consult your doctor
Do not take Carfilnat 60mg Injection without consulting the doctor in case of pregnancy, as it is an unsafe medicine during this period.
Breast Feeding
consult your doctor
Carfilnat 60mg Injection is unsafe to use during breastfeeding as it may cause toxicity to the baby.
Driving
unsafe
Carfilnat 60mg Injection may cause side effects such as dizziness or lack of concentration, which could affect your ability to drive. So it's better to avoid driving or operating heavy machinery.
Kidney
safe if prescribed
Consumption of Carfilnat 60mg Injection should be avoided without informing the doctor if you have any kidney-related issues.
Liver
safe if prescribed
Consumption of Carfilnat 60mg Injection should be avoided without informing the doctor if you have any liver-related issues.
Missed Doses
It is advised not to miss any scheduled dosage of Carfilnat 60mg Injection. In case you miss a dose, consult your doctor immediately.
Don't overdose to compensate for the missed one. Contact your doctor or any healthcare provider and seek medical attention immediately in such cases.
Quick Tips
It is advised to use effective birth control ways and avoid pregnancy during the treatment with Carfilnat Injection.
A person should avoid smoking while undergoing treatment with Carfilnat Injection. Smoking may reduce the effectiveness of medicine.
Monitor your blood sugar & pressure, Kidney & Liver function (KFT & LFT), Heart function at proper intervals after taking Carfilnat 60mg Injection.
Skin becomes extremely sensitive after taking Carfilnat Injection. It is advised to cover your skin exposed to direct sun rays and use high SPF sunscreen before going out.
It is advised to avoid taking analgesics/ antacids (medicines used to neutralize the stomach acid) while taking Carfilnat, as it may reduce the effectiveness of the medicine.
Keep your body hydrated as Diarrhea is one of the common side effects experienced after taking Carfilnat 60mg Injection. Consult your doctor if it doesn't stop or if blood appears in your stools.
If you experience any kind of symptoms after taking Carfilnat 60mg Injection like unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever), or other signs of infection, it is important to Inform your doctor as soon as possible.
Reference
1. Wang, Z., Yang, J., Kirk, C., Fang, Y., Alsina, M., Badros, A., ... & Infante, J. R. (2013). Clinical pharmacokinetics, metabolism, and drug-drug interaction of carfilzomib. Drug Metabolism and Disposition, 41(1), 230-237.
2. Kortuem, K. M., & Stewart, A. K. (2013). Carfilzomib. Blood, The Journal of the American Society of Hematology, 121(6), 893-897.
3.Muchtar, E., Gertz, M. A., & Magen, H. (2016). A practical review on carfilzomib in multiple myeloma. European journal of haematology, 96(6), 564-577.
4. Herndon, T. M., Deisseroth, A., Kaminskas, E., Kane, R. C., Koti, K. M., Rothmann, M. D., ... & Pazdur, R. (2013). US Food and Drug Administration approval: carfilzomib for the treatment of multiple myeloma. Clinical cancer research, 19(17), 4559-4563.
5. Waxman, A. J., Clasen, S., Hwang, W. T., Garfall, A., Vogl, D. T., Carver, J., ... & Weiss, B. M. (2018). Carfilzomib-associated cardiovascular adverse events: a systematic review and meta-analysis. JAMA oncology, 4(3), e174519-e174519.
FAQs
No, Carfilnat Injection does not completely cure blood cancer, but it is a better treatment option. However, it slows down the progression of the cancer cells and improves the survival rate of the patients.
Carfilnat Injection is a potent drug that must be injected intravenously by a doctor or an expert nurse. Do not self-administer it.
Yes, taking Carfilnat injection may lower the platelets, making one more prone to infection. As a result, it leads to low immunity.
No, it is important to tell your doctor if you are taking any prescribed or non-prescribed medicines, vitamins, or supplements. They may interact with the drug and can affect its effectiveness.
Hair loss is the most common side effect observed after taking Carfilnat Injection. Consult your doctor to solve all concerns about hair loss.
Yes, Carfilnat can be used alone or in combination with other drugs to increase the effectiveness of the treatment.
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Author Details
Written By
Venika Choudhary
Medical Content Writer @ Magicine Pharma
I hold an M.Sc. in Microbiology and have a strong academic foundation in microbial sciences and applied biotechnology. I began my career with extensive hands-on research at CSIR laboratories, focusing on fungal enzyme production, studying fungal diversity in various ecosystems, and developing bio-pesticides as sustainable alternatives to chemical pesticides. This work deepened my understanding of fungal biology, bioactive compounds, and their pharmaceutical and agricultural applications. Transitioning from research, I now work as a medical content writer, where I combine my scientific expertise with a passion for clear and reliable healthcare communication. I apply my research background to create patient-friendly, compliant content for pharmaceutical companies and healthcare platforms, ensuring science is both trustworthy and accessible. Specializing in clear, accurate, and engaging content, I help patients make informed decisions and support pharmaceutical companies in delivering trusted information. Whether writing product descriptions, crafting disease awareness articles, or composing drug information leaflets, I consistently meet regulatory standards and address audience needs, making my content an asset for healthcare brands.
Reviewed By
Dr. Aditya Sarin - MBBS, MD, DrNB - Consultant Medical Oncology
Dr. Aditya Sarin, MBBS, MD, DrNB, is a highly qualified medical oncologist with profound research and clinical expertise, currently working at Sir Ganga Ram Hospital, New Delhi. He is also a member of the European Society of Medical Oncology (ESMO), a non-profit European organization dedicated to eradicating cancer by promoting comprehensive cancer care and advancing medical oncology. He has been honored with several awards, including the International Cancer Foundation scholarship (ESMO congress, 2022) and Young Medical Oncologist of the Year (Times of India, 2024). He is well-known for his breakthrough in oncology. Dr. Sarin is passionate about converting complex health information into a concise and clear form that is understandable to everyone, aiming to create awareness and cancer care among people.
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