Carfilnat 60mg Injection
Rx RequiredSalt Composition: Carfilzomib
Expiry Date: 01/2028
Price on Request
Inclusive of all taxes
1 Injection
About The Product
- Relapsed or refractory multiple myeloma
- Proteasome inhibition in cancer therapy
- Combination therapy support
Carfilnat 60mg Injection belongs to the category of anticancer medicines. It is primarily used to treat patients diagnosed with multiple myeloma and mantle-cell lymphoma. The active ingredient of Carfilnat is carfilzomib, which belongs to the drug class of proteasome inhibitors.
Carfilzomib is administered as an injection by an experienced nurse or medical professional. This injection works by killing the cancer cells and reducing the size of the tumor. This injection is usually given in combination with another anticancer medicine as a part of combination therapy to increase the efficacy of the treatment.
Side Effects
Every medicine has some side effects that typically manage on their own as your body gets used to the medicine, but some people may experience severe side effects rarely. In that case, the patient should contact the doctor immediately. Contact your healthcare provider if you face any unusual or persistent side effects. Some common side effects of Carfilnat 60mg Injection include:
- Fever
- Cough
- Fatigue
- Diarrhea
- Headache
- Breathlessness
- Skin inflammation
- Nausea
- Back and muscle pain
- Low levels of RBCs & platelets in the blood
- Dyspnea
- Thrombocytopenia
- Hypertension
- Cardiac events (Cardiac arrest, Heart failure)
How To Use
- Cisplat 10mg Injection is given intravenously by a doctor or trained nurse under strict medical supervision.
- It is not self-administrable.
- The dosage and duration of the treatment are determined by the doctor based on the stage & type of cancer and the patient's health condition.
- Carfilnat Injection may cause dehydration, so increase your fluid intake.
- It can also cause dizziness, making it unsafe to drive or operate machinery.
- To prevent rashes, avoid sun exposure and use sunscreen (SPF 15 or higher) along with protective clothing.
How It Works
- Carfilnat 60mg Injection is an anticancer medication that belongs to the class of drugs known as Proteasome Inhibitors.
- This medication works by blocking proteasomes, which are enzymes responsible for breaking down proteins in cells.
- By inhibiting this process, Carfilnat prevents the growth and multiplication of cancer cells, ultimately leading to their death.
Safety Advice
The interaction of alcohol is not known with Carfilnat 60 mg Injection; therefore, consult your doctor regarding this.
Carfilnat 60 mg Injection can cause harm to an unborn baby if given during pregnancy. It is essential to avoid pregnancy during treatment and for several months afterward. Before starting therapy, discuss effective contraception with your doctor, and inform them immediately if you or your partner becomes pregnant while on treatment.
Carfilnat 60mg Injection is unsafe to use during breastfeeding as it may cause toxicity to the baby.
Carfilnat 60mg Injection may cause side effects such as dizziness or lack of concentration, which could affect your ability to drive. So it's better to avoid driving or operating heavy machinery.
Consumption of Carfilnat 60mg Injection should be avoided without informing the doctor if you have any kidney-related issues.
Consumption of Carfilnat 60mg Injection should be avoided without informing the doctor if you have any liver-related issues.
Missed Doses
- It is advised not to miss any scheduled dosage of Carfilnat 60mg Injection.
- In case you miss a dose, consult your doctor immediately.
- Don't overdose to compensate for the missed one.
- Contact your doctor or any healthcare provider and seek medical attention immediately in such cases.
Quick Tips
It is advised to use effective birth control ways and avoid pregnancy during the treatment with Carfilnat Injection.
A person should avoid smoking while undergoing treatment with Carfilnat Injection. Smoking may reduce the effectiveness of medicine.
Monitor your blood sugar & pressure, Kidney & Liver function (KFT & LFT), Heart function at proper intervals after taking Carfilnat 60mg Injection.
Skin becomes extremely sensitive after taking Carfilnat Injection. It is advised to cover your skin exposed to direct sun rays and use high SPF sunscreen before going out.
It is advised to avoid taking analgesics/ antacids (medicines used to neutralize the stomach acid) while taking Carfilnat, as it may reduce the effectiveness of the medicine.
Keep your body hydrated as Diarrhea is one of the common side effects experienced after taking Carfilnat 60mg Injection. Consult your doctor if it doesn't stop or if blood appears in your stools.
If you experience any kind of symptoms after taking Carfilnat 60mg Injection like unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever), or other signs of infection, it is important to Inform your doctor as soon as possible.
Reference
1. Wang, Z., Yang, J., Kirk, C., Fang, Y., Alsina, M., Badros, A., ... & Infante, J.
R. (2013).
Clinical pharmacokinetics, metabolism, and drug-drug interaction of carfilzomib. Drug Metabolism and Disposition, 41(1), 230-237 - https://pubmed.ncbi.nlm.nih.gov/23118326/ 2.
Kortuem, K. M., & Stewart, A.
K. (2013).
Carfilzomib. Blood, The Journal of the American Society of Hematology, 121(6), 893-897.
3.Muchtar, E., Gertz, M. A., & Magen, H.
(2016). A practical review on carfilzomib in multiple myeloma.
European journal of haematology, 96(6), 564-577 - https://pubmed.ncbi.nlm.nih.gov/26893241/ 4. Herndon, T.
M., Deisseroth, A., Kaminskas, E., Kane, R. C., Koti, K.
M., Rothmann, M. D., ... & Pazdur, R.
(2013). US Food and Drug Administration approval: carfilzomib for the treatment of multiple myeloma.
Clinical cancer research, 19(17), 4559-4563. 5.
Waxman, A. J., Clasen, S., Hwang, W.
T., Garfall, A., Vogl, D. T., Carver, J., ... & Weiss, B.
M. (2018).
Carfilzomib-associated cardiovascular adverse events: a systematic review and meta-analysis. JAMA oncology, 4(3), e174519-e174519.
FAQs
No, Carfilnat Injection does not completely cure blood cancer, but it is a better treatment option.
However, it slows down the progression of the cancer cells and improves the survival rate of the patients.
Medical Disclaimer
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