Cizumab 300mg Injection

Cizumab 300mg Injection

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Salt Composition: Bevacizumab

Expiry Date: 01/2028

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12ml/Vial

About The Product

Rectal Cancer, Colorectal Cancer, Chemotherapy, Brain tumor

Description

Cizumab 300mg Injection is an anti-cancer medication used in the treatment of several types of cancer, such as colorectal, rectal, non-small cell lung cancer, ovarian, and brain tumors. Its active ingredient is Bevacizumab, a monoclonal antibody that works by inhibiting vascular endothelial growth factor (VEGF). It works by blocking VEGF, which prevents the formation of new blood vessels that supply nutrients and oxygen to tumors.

The medicine slows or stops the growth of cancer cells in the body. A doctor's prescription is highly required while taking the medications. The exact dosage and duration is only recommended by the healthcare professional.

Uses

  • Colorectal Cancer
  • Rectal Cancer
  • Non-small cell lung Cancer
  • Ovarian Cancer
  • Brain tumor

Side Effects

Every medication has certain side effects. Cizumab 300mg Injection also caused various side effects. Consult the doctor if any of the symptoms persist:

  • Numbness in hands or feet
  • Weakness and lack of energy
  • Diarrhea, nausea, vomiting, abdominal pain
  • Constipation
  • Loss of appetite
  • Weight loss

  • Headache
  • Vision changes
  • Confusion
  • Severe allergic reactions
  • High Blood pressure
  • Delayed wound healing following surgery
  • Protein in urine
  • Severe infections
  • Decrease in counts of white blood cells
  • Fever
  • Dry skin
  • Back pain

How To Use

  • The doctor prescribed Cizumab 300mg Injection to be administered intravenously (IV) under medical supervision.
  • The medicine should be used under medical supervision to ensure a safe and effective treatment option.
  • Do not skip or miss the dose, as it may decrease the effectiveness of the medication.
  • Consult with the doctor on the missed dose.
  • Do not self-administer as improper use may lead to serious side effects.

How It Works

Colorectal, rectal, ovarian, and some other cancers are formed by vascular endothelial growth factor (VEGF), which is a single protein or growth factor that stimulates the growth of new blood vessels (angiogenesis). Cizumab 300mg Injection blocks the protein called VEGF, which helps cancer grow blood vessels.

When the medicine stops VEGF, the tumor receives less blood and oxygen. This slows down or stops the growth and spread of cancer cells in the body.

Safety Advice

Alcohol
Avoid using alcohol while using Cizumab 300mg Injection, as it affects the treatment effectiveness. For more information, consult the doctor.
Pregnancy
Pregnant women should avoid using Cizumab 300mg Injection because the medication contains hard substances that affect the fetus in various ways. It is better to consult with the doctor before using the medication.
Breast Feeding
Cizumab 300mg Injection is not recommended for women who breastfeed their child as the medication is passed through the breast milk, which can harm the baby.
Driving
Cizumab 300mg Injection does not affect driving mode, but if you experience any harmful symptoms, then consult the doctor and follow the guidance as recommended
Kidney
Cizumab 300mg Injection is not recommended for patients with kidney disease as the medicine can interrupt the kidney function and produce complications in the treatment.
Liver
The liver plays an important role in the body. Cizumab 300mg Injection is not recommended for liver patients because it may harm the liver in many ways.

FAQs

Cizumab 300mg Injection is taken by non small cell lung cancer, colorectal cancer, rectal cancer, kidney cancer, ovarian cancer, cervical cancer, and brain tumor by blocking the epidermal growth factor receptor.

The medicine stops the growth and progression of cancer cells in the body.

References

  • McCormack, P. L., & Keam, S. J. (2008). Bevacizumab: a review of its use in metastatic colorectal cancer. Drugs, 68(4), 487-506. https://pubmed.ncbi.nlm.nih.gov/18318567/
  • Burger, R. A., Brady, M. F., Bookman, M. A., Fleming, G. F., Monk, B. J., Huang, H., ... & Liang, S. X. (2011). Incorporation of bevacizumab in the primary treatment of ovarian cancer. New England Journal of Medicine, 365(26), 2473-2483. https://pubmed.ncbi.nlm.nih.gov/22204724/
  • Bakri, S. J., Snyder, M. R., Reid, J. M., Pulido, J. S., & Singh, R. J. (2007). Pharmacokinetics of intravitreal bevacizumab (Avastin). Ophthalmology, 114(5), 855-859. https://pubmed.ncbi.nlm.nih.gov/17467524/
  • Keating, G. M. (2014). Bevacizumab: a review of its use in advanced cancer. Drugs, 74(16), 1891-1925. https://pubmed.ncbi.nlm.nih.gov/25315029/
  • Ferrara, N., Hillan, K. J., Gerber, H. P., & Novotny, W. (2004). Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer. Nature reviews Drug discovery, 3(5), 391-400. https://pubmed.ncbi.nlm.nih.gov/15136787/

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