Cytarzer 500mg Injection

Cytarzer 500mg Injection is an anticancer injection prescribed by the doctor to treat various types of blood cancers including acute myeloid leukemia (AML), acute non-lymphoblastic leukemias, and acute lymphoblastic leukemia (ALL) etc. It is also given to treat blast crises in chronic myeloid leukemia and erythroleukemia. It also helps in the management of Management of meningeal leukemia and meningeal neoplasms via intrathecal administration. Cytarabine is the active ingredient of this medication. It is often combined with other drugs like daunorubicin for remission induction in adults and pediatric patients.

Like any other chemical based medication, Cytarzer 500mg Injection also has multiple side effects that can ranges from common to serious. Immediately contact your doctor if symptoms persist for longer period of time. Seek immediate Medical Attention in case of serious side effects.
● Infections
● Fever
● Cytarabine syndrome
● Nausea
● Vomiting
● Diarrhea
● Abdominal pain
● Loss of appetite
● Mouth sores
● Hair loss
● Skin Reactions
● Fatigue
● Headaches
● Dizziness
● Eye Problems
● Bone Pain
● Fast heartbeat
● Injection site reactions

Cytarzer 500mg Injection is administered intravenously. It can also be administered subcutaneously or intrathecally either alone or with other cancer treatment therapies, depending on the cancer's type and stage. Patients should not self-administer; it must be injected by a doctor or trained nurse. Consult a doctor for precise dosage and timing.

Cytarzer Injection contains 500mg of Cytarabine that works as an antimetabolite chemotherapy.Cytarabine inhibits DNA polymerase, blocking DNA chain elongation, synthesis, and repair during the S-phase of the cell cycle. It also incorporates into DNA and RNA, disrupting replication and causing chain termination. As a result, cancer cells are not able to multiply and eventually reduce in number.

• Liu, J. C., Wang, D., Callen, E., Chen, C., Noriega, S., Shang, Y., ... & Nussenzweig, A. (2025). Mechanism of cytarabine-induced neurotoxicity. Nature, 1-10.
• Poodeh, A. M., Sarab, G. A., Ravari, M. P., Najafzadeh, M., Safarpour, H., Zarban, A., ... & Sajjadi, S. M. (2025). Metformin and chloroquine enhanced the efficacy of cytarabine in acute lymphoblastic leukemia cell lines: a drug repositioning approach. Scientific Reports, 15(1), 16510.
• Karunarathna, I. (2025). Cytarabine in Hematologic Malignancies: Mechanisms, Clinical Applications, Toxicities, and Multidisciplinary Considerations.
• Alzahrani, A. M., Alnuhait, M. A., & Alqahtani, T. (2025). The Clinical Safety and Efficacy of Cytarabine and Daunorubicin Liposome (CPX‐351) in Acute Myeloid Leukemia Patients: A Systematic Review. Cancer Reports, 8(5), e70199.