Dacmed 500mg Injection

Dacmed 500mg Injection

Prescription requiredRx Required

Salt Composition: Dacarbazine

Expiry Date: 01/2028

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1 Injection

About The Product

Skin Cancer

Dacmed 500mg Injection is a chemotherapy-based anticancer medicine. This medicine is primarily used to treat patients diagnosed with metastatic malignant melanoma, a type of skin cancer, soft tissue sarcoma, and Hodgkin lymphoma (cancer that forms in the lymph system). The active ingredient of Dacmed is Dacarbazine, which belongs to the drug class of alkylating agents. It is administered as an injection by an experienced nurse or medical professional.

Side Effects

  • Every medicine has some side effects that typically manage on their own as your body gets used to the medicine, but some people may experience severe side effects rarely.
  • In that case, the patient should contact the doctor immediately.
  • Some common side effects of Carfilnat 60mg Injection include: Nausea Vomiting Hair loss Headache Skin reactions Loss of appetite Vision problems Low levels of RBC, WBC, and platelets Some Serious side effects are: Sore throat Liver problems Allergic reaction Extreme tiredness Numbness of the face Fits, confusion, & lethargy Severe vomiting or diarrhea Contact your doctor immediately if you experience any severe or unusual side effects.

How To Use

  • Dacmed 500mg Injection is given intravenously by a doctor or trained nurse under strict medical supervision.
  • It is not self-administrable.
  • The dosage and duration of the treatment are determined by the doctor based on the stage & type of cancer and the patient's health condition.

How It Works

Dacmed 500mg Injection is an alkylating agent that works by alkylation. It inhibits DNA synthesis, which disturbs the normal functioning of DNA.

This process arrests the growth and proliferation of cancer cells, eventually leading to their death.

Safety Advice

Alcohol
Avoid the consumption of alcohol while taking Dacmed 500mg Injection, as alcohol can reduce the effectiveness of the medicine and worsen the symptoms
Pregnancy
Do not take Dacmed 500mg Injection without consulting the doctor in case of pregnancy, as it is an unsafe medicine during this period.
Breast Feeding
Dacmed 500mg Injection should not be used during breastfeeding as it may harm the baby..
Driving
Dacmed 500mg Injection may cause side effects such as dizziness or lack of concentration, which could affect your ability to drive. So it's better to avoid driving or operating heavy machinery.
Kidney
Consumption of Dacmed 500mg Injection should be avoided without informing the doctor if you have any kidney-related issues. It is safe if prescribed.
Liver
Consumption of Dacmed 500mg Injection should be avoided without informing the doctor if you have any liver-related issues. It is safe if prescribed.

Missed Doses

  • It is advised not to miss any scheduled dosage of Dacmed 500mg Injection.
  • In case you miss a dose, consult your doctor immediately.
  • Don't overdose to compensate for the missed one.
  • Contact your doctor or any healthcare provider and seek medical attention immediately in such cases.

Quick Tips

It is advised to use effective birth control methods and avoid pregnancy during the treatment with Dacmed 500mg Injection.


A person should avoid smoking while undergoing treatment with Dacmed Injection. Smoking may reduce the effectiveness of medicine.


Monitor your blood sugar & pressure, Kidney & Liver function (KFT & LFT), Heart function at proper intervals after taking Dacmed 500mg.


Swelling of hands, lips, and weight gain are some of the side effects observed after taking this injection. To reduce them, the doctor may suggest some medication.


Skin becomes supersensitive after taking Dacmed 500mg Injection. It is advised to cover your skin exposed to direct sun rays and use high SPF sunscreen before going out.


It is advised to avoid taking analgesics/ antacids (medicines used to neutralize the stomach acid) while taking Dacmed Injection, as it may reduce the effectiveness of the medicine.


Keep your body hydrated as Diarrhea is one of the common side effects experienced after taking Dacmed 500mg. Consult your doctor if it doesn't stop or if blood appears in your stools.

FAQs

It is important to store the Dacmed 500mg Injection away from light during both storage and administration.

Exposure to light can cause it to become unstable and reduce its effectiveness.

Reference

1. Keilholz, U., Punt, C.

J., Gore, M., Kruit, W., Patel, P., Lienard, D., ... & Eggermont, A. M.

(2005). Dacarbazine, cisplatin, and interferon-alfa-2b with or without interleukin-2 in metastatic melanoma: a randomized phase III trial (18951) of the European Organisation for Research and Treatment of Cancer Melanoma Group.

Journal of clinical oncology, 23(27), 6747-6755. 2.

Robert, C., Thomas, L., Bondarenko, I., O'Day, S., Weber, J., Garbe, C., ... & Wolchok, J. D.

(2011). Ipilimumab plus dacarbazine for previously untreated metastatic melanoma.

New England Journal of Medicine, 364(26), 2517-2526. 3.

Serrone, L., Zeuli, M., Sega, F. M., & Cognetti, F.

(2000). Dacarbazine-based chemotherapy for metastatic melanoma: thirty-year experience overview.

Journal of experimental & clinical cancer research: CR, 19(1), 21-34. 4.

Ugurel, S., Paschen, A., & Becker, J. C.

(2013). Dacarbazine in melanoma: from a chemotherapeutic drug to an immunomodulating agent.

Journal of Investigative Dermatology, 133(2), 289-292. 5.

Cocconi, G., Bella, M., Calabresi, F., Tonato, M., Canaletti, R., Boni, C., ... & Bacchi, M. (1992).

Treatment of metastatic malignant melanoma with dacarbazine plus tamoxifen. New England Journal of Medicine, 327(8), 516-523.

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