
Denoci OP 60mg Injection
Salt Composition: Denosumab
Expiry Date: 01/2028
Inclusive of all taxes
1 Prefilled Syringe(s)
About The Product
Bone disease
Description
Denoci OP 60mg Injection is a doctor prescribed injection that used to treat osteoporosis in postmenopausal women and men at high fracture risk, as well as bone loss associated with hormone therapies for breast or prostate cancer, long-term glucocorticoid use, multiple myeloma, and bone metastases.Denoci OP 60mg Injection contains contains 60mg of Denosumab that improves overall bone health.
Indication
Osteoporosis
Dosage And Administration
- Denoci OP 60mg Injection is administered subcutaneously (under the skin in the lower abdomen), depending on the cancer stage.
- Patients should not self-administer; it must be injected by a doctor or trained nurse.
- Consult a doctor for precise dosage and timing.
Mechanism Of Action
Denoci OP 60mg Injection contains 60mg of denosumab( a monoclonal antibody) works by binding to RANK ligand (RANKL), a protein essential for osteoclast formation, function, and survival.Denoci OP 60mg Injection reduces bone resorption, increases bone mineral density, and strengthens bone structure in osteoporosis or cancer-related to bone loss.
Faqs
Denoci OP 60mg Injection is mainly used to treat osteoporosis in postmenopausal women and men at high fracture risk, as well as bone loss associated with hormone therapies for breast or prostate cancer, long-term glucocorticoid use, multiple myeloma, and bone metastases.
References
• Pageau, S. C.
(2009, May). Denosumab.
In MAbs (Vol. 1, No.
3, pp. 210-215).
Taylor & Francis. • Cummings, S. R., Martin, J.
S., McClung, M. R., Siris, E.
S., Eastell, R., Reid, I. R., ... & Christiansen, C.
(2009). Denosumab for prevention of fractures in postmenopausal women with osteoporosis.
New England Journal of Medicine, 361(8), 756-765. • Hanley, D. A., Adachi, J.
D., Bell, A., & Brown, V. (2012).
Denosumab: mechanism of action and clinical outcomes. International journal of clinical practice, 66(12), 1139-1146. • Sheedy, K.
C., Camara, M. I., & Camacho, P.
M. (2015).
Comparison of the efficacy, adverse effects, and cost of zoledronic acid and denosumab in the treatment of osteoporosis. Endocrine Practice, 21(3), 275-279.
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