
Denosta 60mg injection
Salt Composition: Denosumab
Expiry Date: 01/2028
Inclusive of all taxes
1 prefilled syringe
About The Product
Bone disease
Description
Denosta 60mg Injection is a doctor prescribed injection that used to treat bone related problems associated with multiple cancers such as Multiple Myeloma, Bone metastases from solid tumours and giant cell tumour of the bone (GCTB) .Denosta 60mg Injection contains 60mg of Denosumab that improves overall bone health.
Common Side Effects
• Musculoskeletal pain
• Pain in extremities
• Headache
• Constipation
• Rash
• Nerve pain
• Back pain
• Joint pain
• Abdominal discomfort
• Urinary tract infection
• Respiratory tract infection
• Hair loss
• Eczema
• Injection site reactions
• Osteonecrosis of the jaw
• Hypocalcemia
Dosage And Administration
- Denosta 60mg Injection is administered subcutaneously (under the skin in the lower abdomen), depending on the cancer stage.
- Patients should not self-administer; it must be injected by a doctor or trained nurse.
- Consult a doctor for precise dosage and timing.
Mechanism Of Action
Denosta 60mg Injection contains 60mg of denosumab( a monoclonal antibody) works by binding to RANK ligand (RANKL), a protein essential for osteoclast formation, function, and survival.Denoci OP 60mg Injection reduces bone resorption, increases bone mineral density, and strengthens bone structure in osteoporosis or cancer-related to bone loss.
Faqs
Denosta 60mg Injection is used to treat bone related problems associated with multiple cancers such as Multiple Myeloma, Bone metastases from solid tumours and giant cell tumour of the bone (GCTB).
References
• Pageau, S. C.
(2009, May). Denosumab.
In MAbs (Vol. 1, No.
3, pp. 210-215).
Taylor & Francis. • Cummings, S. R., Martin, J.
S., McClung, M. R., Siris, E.
S., Eastell, R., Reid, I. R., ... & Christiansen, C.
(2009). Denosumab for prevention of fractures in postmenopausal women with osteoporosis.
New England Journal of Medicine, 361(8), 756-765. • Hanley, D. A., Adachi, J.
D., Bell, A., & Brown, V. (2012).
Denosumab: mechanism of action and clinical outcomes. International journal of clinical practice, 66(12), 1139-1146. • Sheedy, K.
C., Camara, M. I., & Camacho, P.
M. (2015).
Comparison of the efficacy, adverse effects, and cost of zoledronic acid and denosumab in the treatment of osteoporosis. Endocrine Practice, 21(3), 275-279.
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