Denub 60mg Injection
Prescription Required
Marketed By
alkem
Pack of
1 Vial
Salt Composition
Denosumab
Storage
Keep in cold place
₹6300₹8085.94
22.09% Off
Inclusive of all taxes
1

Denub 60mg Injection
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Indication
Bone Disease
Description
Denub 60mg Injection is a doctor prescribed injection that used to treat osteoporosis in postmenopausal women and men at high fracture risk, as well as bone loss associated with hormone therapies for breast or prostate cancer, long-term glucocorticoid use, multiple myeloma, and bone metastases.Denub 60mg Injection contains contains 60mg of Denosumab that improves overall bone health.
Common Side Effects
• Musculoskeletal pain
• Pain in extremities
• Headache
• Constipation
• Rash
• Nerve pain
• Back pain
• Joint pain
• Abdominal discomfort
• Urinary tract infection
• Respiratory tract infection
• Hair loss
• Eczema
• Injection site reactions
• Osteonecrosis of the jaw
• Hypocalcemia
Dosage And Administration
Denub 60mg Injection is administered subcutaneously (under the skin in the lower abdomen), depending on the cancer stage. Patients should not self-administer; it must be injected by a doctor or trained nurse. Consult a doctor for precise dosage and timing.
Mechanism Of Action
Denub 60mg Injection contains 60mg of denosumab( a monoclonal antibody) works by binding to RANK ligand (RANKL), a protein essential for osteoclast formation, function, and survival.Denub 60mg Injection reduces bone resorption, increases bone mineral density, and strengthens bone structure in osteoporosis or cancer-related to bone loss.
Faqs
Denub 60mg Injection is used to treat osteoporosis in postmenopausal women and men at high fracture risk, as well as bone loss associated with hormone therapies for breast or prostate cancer, long-term glucocorticoid use, multiple myeloma, and bone metastases.
Denub 60mg Injection contains denosumab( a monoclonal antibody) works by binding to RANK ligand (RANKL), a protein essential for osteoclast formation, function, and survival.
No, it is not advised to self administer the Denub 60mg Injection until and unless you yourself are not a doctor or professional, experienced health care personnel.
No, Denub 60mg Injection is not recommended for administration during pregnancy. It causes harm to developing baby in the womb.
Yes, there are serious side effects of Denub 60mg Injection such as osteonecrosis of the jaw, a typical femoral fractures, hypocalcemia (low calcium), and severe skin reactions. These side effects require immediate medical attention.
References
• Pageau, S. C. (2009, May). Denosumab. In MAbs (Vol. 1, No. 3, pp. 210-215). Taylor & Francis.
• Cummings, S. R., Martin, J. S., McClung, M. R., Siris, E. S., Eastell, R., Reid, I. R., ... & Christiansen, C. (2009). Denosumab for prevention of fractures in postmenopausal women with osteoporosis. New England Journal of Medicine, 361(8), 756-765.
• Hanley, D. A., Adachi, J. D., Bell, A., & Brown, V. (2012). Denosumab: mechanism of action and clinical outcomes. International journal of clinical practice, 66(12), 1139-1146.
• Sheedy, K. C., Camara, M. I., & Camacho, P. M. (2015). Comparison of the efficacy, adverse effects, and cost of zoledronic acid and denosumab in the treatment of osteoporosis. Endocrine Practice, 21(3), 275-279.
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MARKETER DETAILS
alkem
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