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Rituximab 500mg Injection

Rituximab 500mg Injection

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Refrigerated 2–8°C · Online payment only

Salt Composition: rituximab

Expiry Date: 01/2028

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1 Vial

About The Product

Blood Cancer

Rituximab 500mg Injection is used to cure various types of cancer (such as non-Hodgkin's lymphoma, and chronic lymphocytic leukemia). It works by slowing down or preventing the growth of cancer cells.

Description

Rituximab 500mg Injection is a monoclonal antibody. It is used to treat many types of cancers such as to treat non-hodgkin’s lymphoma and chronic lymphocytic leukemia.

It is also indicated to treat moderate-to-severe rheumatoid arthritis in patients. Its active ingredient is rituximab which belongs to the group class of anti-CD20 monoclonal antibodies (immunosuppressive agents).

It works by binding to the CD20 antigen on B cells. The effect helps control B cell proliferation in cancers and modulate immune responses in certain autoimmune disorders.

The dosage and administration must be followed as directed by the healthcare professional to ensure safe and effective treatment option.

Uses

Non- hodgkin's lymphoma, chronic lymphocytic leukemia and moderate to severe rheumatoid arthritis


Side Effects

  • Rituximab 500mg Injection can cause certain side effects some are acute and some are mild.
  • If any of the symptoms persist or worsen, consult the healthcare professional instantly: • Anemia • Muscle spasm • Headache • Urinary tract infection • Fever, chills, and shivering • Inflammation of nasal cavities • Cough, sore throat • Loss of hair • Swelling in the face and body • Diarrhea and nausea • Itchy skin • Increased or decreased blood pressure • Chest pain • Hypersensitivity reactions • Hepatitis B viral infection • Memory loss, trouble thinking, difficulty walking

How To Use

  • Rituximab 500mg Injection can be taken with or without food at the fixed time everyday to enhance the effectiveness of the treatment. It can be taken by a nurse in a hospital through the skin through intravenous infusion into a vein under medical supervision.
  • Consult the healthcare professional about the correct dosage and duration to ensure safe and effective treatment option.
    ​

How It Works

  • Rituximab 500mg Injection is an anticancer medication that binds to the CD20 antigen on B lymphocytes. After binding it causes B cell destruction through complement-dependent cytotoxicity (CDC), antibody-dependent cellular cytotoxicity (ADCC), and direct apoptosis.
  • This leads to depletion of CD20 positive B cells while sparing stem cells. As a result, it blocks B cells and reduce the size of cancer cells in the body.
    ​

Safety Advice

Alcohol
Rituximab 500mg Injection may cause certain side effects while consuming alcohol. Consult the doctor if the symptoms persist.
Pregnancy
Pregnant women should consult the healthcare supervision whether if Rituximab 500mg Injection should be taken or not to avoid complications during the treatment.
Breast Feeding
Rituximab 500mg Injection is passed through the breast milk which is harmful for the baby. So consult your doctor first.
Driving
Driving should avoid while taking Rituximab 500mg Injection as it may cause dizziness and Weakness. Also avoid using machinery while using the medication.
Kidney
Rituximab 500mg Injection may interfere with the kidney function. If the person is a kidney patient, they should take a proper prescription to the doctor.
Liver
Rituximab 500mg Injection may harmful for liver patient as it can be disrupt the liver function and harm the liver in many ways. It is necessary to consult a healthcare professional before using the injection.

FAQs

Rituximab 500mg Injection can be taken with other medication but the doctor prescription as doctor will decide the dosage and duration with other medication based on the patient medical history and response to the treatment.

References

  • Grillo-López, A. J., Hedrick, E., Rashford, M., & Benyunes, M. (2002, February). Rituximab: ongoing and future clinical development. In Seminars in oncology (Vol. 29, No. 1, pp. 105-112). WB Saunders. https://www.sciencedirect.com/science/article/abs/pii/S0093775402500853
  • Cohen, M. D., & Keystone, E. (2015). Rituximab for rheumatoid arthritis. Rheumatology and therapy, 2(2), 99-111. https://pubmed.ncbi.nlm.nih.gov/27747531/
  • Borker, A., & Choudhary, N. (2011). Rituximab. Indian pediatrics, 48(8), 627-632. https://pubmed.ncbi.nlm.nih.gov/21918268/
  • Maloney, D. G., Smith, B., & Rose, A. (2002, February). Rituximab: mechanism of action and resistance. In Seminars in oncology (Vol. 29, No. 1, pp. 2-9). WB Saunders. https://pubmed.ncbi.nlm.nih.gov/11842383/
  • Rezvani, A. R., & Maloney, D. G. (2011). Rituximab resistance. Best practice & research Clinical haematology, 24(2), 203-216. https://pubmed.ncbi.nlm.nih.gov/21658619/​

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