Abirapro 250mg Tablet
Prescription Required
Marketed By
glenmark
Pack of
120 Tablet in Bottle
Salt Composition
Abiraterone Acetate
Storage
Keep in cold place
₹6000₹26250
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Abirapro 250mg Tablet
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Overview
Abirapro is a hormonal anticancer medication containing abiraterone acetate (250 mg). It is used primarily to treat advanced prostate cancer in adult men. It is a steroidal derivative of Progesterone for the treatment of patients with hormone-refractory prostate cancer. It may also be used to treat other conditions, as determined by the doctor. It is sometimes used in combination with certain other medicines as part of a chemotherapy regimen. When Abirapro 250mg Tablet is prescribed for an early stage of this disorder, it is used with testosterone-lowering treatment. This medicine is not for use in women or children.
Indication
Prostate Cancer
Uses of Abirapro 250mg Tablet
Used in adult men for:
Metastatic castration‑resistant prostate
cancer (mCRPC).
High‑risk metastatic castration‑sensitive
prostate cancer (mCSPC).
Must be used: in combination with prednisone or prednisolone, and together with androgen-deprivation therapy (ADT) or post-orchiectomy.
Common Side effects of Abirapro 250mg Tablet
The human body takes some time to adjust after consuming the medicine. Not every side effect requires medical assistance. If you observe, there are serious changes that cannot be handled well by the patient, consult your doctor immediately. Common side effects are mentioned below:
- High blood pressure
- Low potassium
- Liver enzyme elevation
- Fluid retention (swelling)
- Fatigue, joint pain, diarrhea
Dosage and Administration
Abirapro 250mg Tablet should be taken on an empty stomach, at least 2 hours before or 1 hour after food. Taking it with food may increase the blood levels of Abirapro 250mg Tablet, which may cause side effects. You should take it exactly as your doctor has advised. Your doctor will decide the dose and duration of Abirapro 250mg Tablet.
Mechanism of action - Abirapro 250mg Tablet
Abirapro works by blocking an enzyme (CYP17) involved in producing androgens (male hormones) like testosterone. Prostate cancer cells rely on these hormones to grow, so reducing them slows or stops the cancer's progression.
Safety Advice for Abirapro 250mg Tablet
Alcohol
consult your doctor
Avoid the intake of alcohol when the treatment is going on. Consult the doctor before taking this medication.
Pregnancy
risky
Abirapro 250mg Tablet is not indicated to be used during pregnancy, as advised by the doctor. Women who are pregnant or who may become pregnant should not touch this medication without gloves.
Breast Feeding
precaution
Abirapro 250mg Tablet is not indicated to be use in breastfeeding women. Inform your doctor if you are breastfeeding before starting treatment with this medication.
Driving
unsafe
You may feel dizzy after consuming the medicine. So, avoid driving and operating any heavy machinery.
Kidney
caution
Share your medical history with the doctor in case of any kidney problems.
Liver
protective
Do not consume Abirapro 250 mg tablet in case of liver disease. Consult your doctor first.
Missed Doses
Try not to miss any dose of Abirapro 250 mg tablet. In case you missed it, do not overdose. Follow the regular schedule and consult your doctor immediately.
FAQs
Abirapro is an anti-cancer hormonal treatment drug. It is not administered for curing cancer but enables prolonging and improving life by curbing the spread of cancer in male patients suffering from prostate cancer.
Abirapro should be strictly taken as per your prescription from the doctor treating you with specific cancer. It is advisable not to change or stop your dose without prior discussion/suggestion from your doctor. The medicine should be taken on an empty stomach.
Abirapro may cause various side effects or use interactions if administered with other medicines, vitamins, and herbal supplements. Before starting Abirapro, your doctor should be completely aware of your medical history, previous ongoing treatments, and prescriptions.
Abirapro is not a cancer treatment drug. It is a hormonal treatment to slow down the growth of prostate cancer cells in men. Specific studies to prove its efficiency/cure in any other type of cancer are yet not available.
Yes, Abirapro is advised to be taken on an empty stomach to curb the side effects of the medicine when taken with food. Adverse effects such as high blood pressure, muscle weakness, paralysis, and breathing difficulties are common symptoms noticed if medicine is taken along with food. The interval of 1 hour before meal and 2 hours after meal is advised for administration of the medicine.
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Reference
Auchus, R. J., Yu, M. K., Nguyen, S., & Mundle, S. D. (2014). Use of prednisone with abiraterone acetate in metastatic castration-resistant prostate cancer. The oncologist, 19(12), 1231-1240.
Cancer Research UK. 2024. Together we will beat cancer. 2024. Steroids (dexamethasone, prednisolone,methylprednisolone and hydrocortisone). https://www.cancerresearchuk.org/about-cancer/treatment/drugs/steroids.
Fizazi, K., Tran, N., Fein, L., Matsubara, N., Rodriguez-Antolin, A., Alekseev, B. Y., ... & Chi, K. N. (2017). Abiraterone plus prednisone in metastatic, castration-sensitive prostate cancer. New England Journal of Medicine, 377(4), 352-360.
Jena, B. R., Panda, S. P., Kulandaivelu, U., Alavala, R. R., Rao, G. K., Swain, S., ... & Ghose, D. (2021). AQbD driven development of an RP-HPLC method for the quantitation of abiraterone acetate for its pharmaceutical formulations in the presence of degradants. Turkish journal of pharmaceutical sciences, 18(6),
718.
Kaler, J., Hussain, A., Haque, A., Naveed, H., & Patel, S. (2020). A comprehensive review of pharmaceutical and surgical interventions of prostate cancer. Cureus, 12(11).
Kumar, S., Joshi, A., Takke, A., Varghese, D., Pathak, S., Noronha, V., ... & Gota, V. (2025). Comparison of PSA Response to Generic Versus Innovator (Zytiga) Formulations of Abiraterone in Metastatic CRPC: A Retrospective Analysis. Indian Journal of Medical and Paediatric Oncology.
National cancer institute. 2023. Abiraterone acetate. https://www.cancer.gov/about-cancer/treatment/drugs/abirateroneacetate.
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