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Afanat 20mg tablets

4.8
Google Rating

Prescription Required

Marketed By

Natco

Pack of

28

Salt Composition

Afatinib

Storage

Keep in cold place

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Afanat 20mg tablets

Afanat 20mg tablets

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Overview

Afanat 20mg Tablet contains afatinib dimaleate as an active ingredient. It is an anticancer medicine used to treat patients with non-small cell lung cancer (NSCLC) whose tumors have certain abnormal epidermal growth factor receptor (EGFR) genes, and patients with metastatic, squamous NSCLC progressing after platinum-based chemotherapy.

Indication

Lung Cancer

Uses

Benefits

Non-small cell lung cancer (NSCLC)

Side Effects


How To Use

Undesired symptoms or responses vary from person to person as the human body reacts differently to the Afanat 20 mg Tablet, but they typically resolve naturally within a few days as the body adjusts to the medicine, requiring no medical attention. In case these symptoms don't go away and you face severe side effects, then immediately consult your doctor or medical team. Some of the common side effects of the Afanat 20 mg Tablet are:
Infection
Headache,
Fever
Loss of appetite
Rash
High blood pressure
Dry skin
lack of sleep.
Vomiting
Indigestion
Nausea
Kidney damage diarrhea, or constipation

How It Works

Afanat 20mg Tablet is taken once a day regularly at the same time each day to increase its effectiveness. It is an oral medication that can be taken with or without food. The capsules should not be chewed, opened, or crushed; they should be swallowed.

Safety Advice

Alcohol

Alcohol

consult your doctor

Excessive alcohol consumption can decrease the immunity of the individual and weaken the liver function. However, moderate levels of alcohol do not interfere with the working of the Afanat 20mg Tablet, as per the research.
Pregnancy

Pregnancy

consult your doctor

The Afanat 20 mg Tablet should be injected after consulting the doctor; during pregnancy, it is not suggested to take it routinely. Afanat 20 mg Tablet can be injected in case of severe, life-threatening conditions. However, it may harm the unborn.
Breast Feeding

Breast Feeding

consult your doctor

The Afanat 20 mg Tablet is considered unsafe to be taken while breastfeeding, as there is a chance that it may pass to the developing baby through the breast milk of the mother. It is generally considered unsafe, and there is no clear evidence found in the clinical data on how it harms the baby.
Driving

Driving

unsafe

Driving after taking the Afanat 20 mg Tablet may affect or interfere with driving ability or distract while operating machinery. With fever or dizziness, neurological effects can be seen after taking the capsule. Avoid driving until you feel better.
Kidney

Kidney

safe if prescribed

People with kidney issues can use the Afanat 20 mg Tablet after consulting with the doctor. It may harm the kidneys if taken on self-medication. The capsule contains afatinib, which belongs to a rare case of acute kidney injury (AKI).
Liver

Liver

safe if prescribed

The Afanat 20 mg Tablet is generally considered unsafe for people with mild to moderate liver disease. Although regular monitoring of the enzyme is required. The dose should be adjusted; take it with caution.

Missed Doses

Quick Tips

FAQs

What information should be told to the doctor before taking an Afanat 20 mg tablet?

Inform the doctor if you are allergic to the ingredient present in the Afanat 20 mg Tablet, in case of high sugar level, pregnancy or breastfeeding, or a weakened immune system. Patient with medical history or medication.

What precautions must be taken before taking an Afanat 20 mg tablet?

As the capsule suppresses the immune system, the risk of infection increases. Afanat 20 mg Tablet can increase the risk of getting cancer, such as lymph gland cancer (lymphoma) and skin cancer. It can lower the body's ability to fight infections.

Is Afanat 20 mg Tablet an antibiotic?

No, Afanat 20mg Tablet is an anti-cancer medication (specifically a kinase inhibitor or targeted therapy drug) used to treat certain types of non-small cell lung cancer.

Can I drink alcohol while taking the Afanat 20 mg Tablet?

It is advised not to take alcohol while taking the Afanat 20 mg Tablet, because consuming alcohol can cause serious side effects and can damage your liver badly. Consult your doctor if you have concerns or queries.

I forgot to take the Afanat 20 mg tablet. What to do?

As soon as you remember, take the missed dose unless it's time for your next dose. You should never take a double dose to make up for a missed one

What are the side effects of the Afanat 20 mg Tablet?

Common side effects of the Afanat 20 mg Tablet are constipation, muscle pain, swelling, nausea, diarrhea, infection, loss of appetite, hair loss, vomiting, and weakness.

How long does the treatment with Afanat 20 mg Tablet last?

The doctor decides how long the treatment with the Afanat 20 mg tablet will continue, depending on the stage and health of the patient.

Is it safe to take this Afanat 20 mg tablet during pregnancy or breastfeeding?

During pregnancy, it is not safe to take Afanat 20 mg Tablet, as it can cause harm to the unborn baby. Furthermore, during breastfeeding, this medicine must not be used. Please make sure to consult your healthcare provider regarding the same.

How does the Afanat 20 mg Tablet work?

Afanat 20 mg Tablet works by inhibiting or binding with the enzyme receptors (EGFR, HER2, and HER4). It causes the downregulation of signaling pathways, stopping or slowing the spread of cancer.

Reference

Brückl WM, Reck M, Griesinger F, Schäfer H, Kortsik C, Gaska T, Rawluk J, Krüger S, Kokowski K, Budweiser S, Ficker JH, Hoffmann C, Schüler A, Laack E. (2023). Afatinib as first-line treatment in patients with EGFR-mutated non-small cell lung cancer in routine clinical practice. Ther Adv Med Oncol.;13.
Inoue, A., Kobayashi, K., Usui, K., Maemondo, M., Okinaga, S., Mikami, I., & Hagiwara, K. (2025). First-line gefitinib for patients with advanced non–non-small-cell lung cancer harboring epidermal growth factor receptor mutations without indication for chemotherapy. Journal of Clinical Oncology, 27(9), 1394-1400.
Kim, Y., Lee, S. H., Ahn, J. S., Ahn, M. J., Park, K., & Sun, J. M. (2025). Efficacy and safety of afatinib for EGFR-mutant non-small cell lung cancer, compared with gefitinib or erlotinib. Cancer research and treatment: official journal of Korean Cancer
Association, 51(2), 502-509.
Miura, S., Tanaka, H., Misumi, T., Yoshioka, H., Tokito, T., Fukuhara, T., & Thoracic Oncology Research Group and all ACHILLES investigators. (2025). Pragmatic randomized study of afatinib versus chemotherapy for patients with non–small cell lung cancer with uncommon epidermal growth factor receptor mutations: ACHILLES/TORG1834. Journal of Clinical Oncology, 43(18), 2049-2058.
Schuler, M., Wu, Y. L., Hirsh, V., O’Byrne, K., Yamamoto, N., Mok, T., & Yang, J. C. H. (2024). First-line afatinib versus chemotherapy in patients with non–small cell lung cancer and common epidermal growth factor receptor gene mutations and brain metastases. Journal of Thoracic Oncology, 11(3), 380-390.

Ratings And Reviews

4.8
Google Rating

4.80/5

5 Ratings

5

80.00%

4

20.00%

3

0.00%

2

0.00%

1

0.00%

Riya Kumar

Satisfied with the purchase

Reliable product. Afanat 20mg tablets has been serving me well. The quality is good and delivery was timely. Good value for money and I'm satisfied with my purchase.

a year ago

John Davis

Very satisfied with purchase

Excellent service and product quality! Afanat 20mg tablets is reliable and works perfectly. The packaging was secure and delivery was on time. Great experience overall!

9 months ago

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MARKETER DETAILS

Natco

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