Afanat 20mg tablets

Afanat 20mg tablets

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Salt Composition: Afatinib

Expiry Date: 01/2028

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About The Product

Lung Cancer

Afanat 20mg Tablet contains afatinib dimaleate as an active ingredient. It is an anticancer medicine used to treat patients with non-small cell lung cancer (NSCLC) whose tumors have certain abnormal epidermal growth factor receptor (EGFR) genes, and patients with metastatic, squamous NSCLC progressing after platinum-based chemotherapy.

Benefits

Non-small cell lung cancer (NSCLC)

How To Use

  • Undesired symptoms or responses vary from person to person as the human body reacts differently to the Afanat 20 mg Tablet, but they typically resolve naturally within a few days as the body adjusts to the medicine, requiring no medical attention.
  • In case these symptoms don't go away and you face severe side effects, then immediately consult your doctor or medical team.
  • Some of the common side effects of the Afanat 20 mg Tablet are: Infection Headache, Fever Loss of appetite Rash High blood pressure Dry skin lack of sleep.
  • Vomiting Indigestion Nausea Kidney damage diarrhea, or constipation

How It Works

Afanat 20mg Tablet is taken once a day regularly at the same time each day to increase its effectiveness. It is an oral medication that can be taken with or without food.

The capsules should not be chewed, opened, or crushed; they should be swallowed.

Safety Advice

Alcohol
Excessive alcohol consumption can decrease the immunity of the individual and weaken the liver function. However, moderate levels of alcohol do not interfere with the working of the Afanat 20mg Tablet, as per the research.
Pregnancy
The Afanat 20 mg Tablet should be injected after consulting the doctor; during pregnancy, it is not suggested to take it routinely. Afanat 20 mg Tablet can be injected in case of severe, life-threatening conditions. However, it may harm the unborn.
Breast Feeding
The Afanat 20 mg Tablet is considered unsafe to be taken while breastfeeding, as there is a chance that it may pass to the developing baby through the breast milk of the mother. It is generally considered unsafe, and there is no clear evidence found in the clinical data on how it harms the baby.
Driving
Driving after taking the Afanat 20 mg Tablet may affect or interfere with driving ability or distract while operating machinery. With fever or dizziness, neurological effects can be seen after taking the capsule. Avoid driving until you feel better.
Kidney
People with kidney issues can use the Afanat 20 mg Tablet after consulting with the doctor. It may harm the kidneys if taken on self-medication. The capsule contains afatinib, which belongs to a rare case of acute kidney injury (AKI).
Liver
The Afanat 20 mg Tablet is generally considered unsafe for people with mild to moderate liver disease. Although regular monitoring of the enzyme is required. The dose should be adjusted; take it with caution.

FAQs

Inform the doctor if you are allergic to the ingredient present in the Afanat 20 mg Tablet, in case of high sugar level, pregnancy or breastfeeding, or a weakened immune system.

Patient with medical history or medication.

Reference

Brückl WM, Reck M, Griesinger F, Schäfer H, Kortsik C, Gaska T, Rawluk J, Krüger S, Kokowski K, Budweiser S, Ficker JH, Hoffmann C, Schüler A, Laack E. (2023).

Afatinib as first-line treatment in patients with EGFR-mutated non-small cell lung cancer in routine clinical practice. Ther Adv Med Oncol.;13.

Inoue, A., Kobayashi, K., Usui, K., Maemondo, M., Okinaga, S., Mikami, I., & Hagiwara, K. (2025).

First-line gefitinib for patients with advanced non–non-small-cell lung cancer harboring epidermal growth factor receptor mutations without indication for chemotherapy. Journal of Clinical Oncology, 27(9), 1394-1400.

Kim, Y., Lee, S. H., Ahn, J.

S., Ahn, M. J., Park, K., & Sun, J.

M. (2025).

Efficacy and safety of afatinib for EGFR-mutant non-small cell lung cancer, compared with gefitinib or erlotinib. Cancer research and treatment: official journal of Korean Cancer Association, 51(2), 502-509.

Miura, S., Tanaka, H., Misumi, T., Yoshioka, H., Tokito, T., Fukuhara, T., & Thoracic Oncology Research Group and all ACHILLES investigators. (2025).

Pragmatic randomized study of afatinib versus chemotherapy for patients with non–small cell lung cancer with uncommon epidermal growth factor receptor mutations: ACHILLES/TORG1834. Journal of Clinical Oncology, 43(18), 2049-2058.

Schuler, M., Wu, Y. L., Hirsh, V., O’Byrne, K., Yamamoto, N., Mok, T., & Yang, J.

C. H.

(2024). First-line afatinib versus chemotherapy in patients with non–small cell lung cancer and common epidermal growth factor receptor gene mutations and brain metastases.

Journal of Thoracic Oncology, 11(3), 380-390.

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