Marketed By
Natco
Pack of
28
Salt Composition
Afatinib
Storage
Keep in cold place
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Afanat 20mg tablets
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Overview
Afanat 20mg Tablet contains afatinib dimaleate as an active ingredient. It is an anticancer medicine used to treat patients with non-small cell lung cancer (NSCLC) whose tumors have certain abnormal epidermal growth factor receptor (EGFR) genes, and patients with metastatic, squamous NSCLC progressing after platinum-based chemotherapy.
Indication
Lung Cancer
Uses
Benefits
Non-small cell lung cancer (NSCLC)
Side Effects
How To Use
Undesired symptoms or responses vary from person to person as the human body reacts differently to the Afanat 20 mg Tablet, but they typically resolve naturally within a few days as the body adjusts to the medicine, requiring no medical attention. In case these symptoms don't go away and you face severe side effects, then immediately consult your doctor or medical team. Some of the common side effects of the Afanat 20 mg Tablet are:
Infection
Headache,
Fever
Loss of appetite
Rash
High blood pressure
Dry skin
lack of sleep.
Vomiting
Indigestion
Nausea
Kidney damage diarrhea, or constipation
How It Works
Afanat 20mg Tablet is taken once a day regularly at the same time each day to increase its effectiveness. It is an oral medication that can be taken with or without food. The capsules should not be chewed, opened, or crushed; they should be swallowed.
Safety Advice

Alcohol
consult your doctor

Pregnancy
consult your doctor

Breast Feeding
consult your doctor

Driving
unsafe

Kidney
safe if prescribed

Liver
safe if prescribed
Missed Doses
Quick Tips
FAQs
Inform the doctor if you are allergic to the ingredient present in the Afanat 20 mg Tablet, in case of high sugar level, pregnancy or breastfeeding, or a weakened immune system. Patient with medical history or medication.
As the capsule suppresses the immune system, the risk of infection increases. Afanat 20 mg Tablet can increase the risk of getting cancer, such as lymph gland cancer (lymphoma) and skin cancer. It can lower the body's ability to fight infections.
No, Afanat 20mg Tablet is an anti-cancer medication (specifically a kinase inhibitor or targeted therapy drug) used to treat certain types of non-small cell lung cancer.
It is advised not to take alcohol while taking the Afanat 20 mg Tablet, because consuming alcohol can cause serious side effects and can damage your liver badly. Consult your doctor if you have concerns or queries.
As soon as you remember, take the missed dose unless it's time for your next dose. You should never take a double dose to make up for a missed one
Common side effects of the Afanat 20 mg Tablet are constipation, muscle pain, swelling, nausea, diarrhea, infection, loss of appetite, hair loss, vomiting, and weakness.
The doctor decides how long the treatment with the Afanat 20 mg tablet will continue, depending on the stage and health of the patient.
During pregnancy, it is not safe to take Afanat 20 mg Tablet, as it can cause harm to the unborn baby. Furthermore, during breastfeeding, this medicine must not be used. Please make sure to consult your healthcare provider regarding the same.
Afanat 20 mg Tablet works by inhibiting or binding with the enzyme receptors (EGFR, HER2, and HER4). It causes the downregulation of signaling pathways, stopping or slowing the spread of cancer.
Reference
Brückl WM, Reck M, Griesinger F, Schäfer H, Kortsik C, Gaska T, Rawluk J, Krüger S, Kokowski K, Budweiser S, Ficker JH, Hoffmann C, Schüler A, Laack E. (2023). Afatinib as first-line treatment in patients with EGFR-mutated non-small cell lung cancer in routine clinical practice. Ther Adv Med Oncol.;13.
Inoue, A., Kobayashi, K., Usui, K., Maemondo, M., Okinaga, S., Mikami, I., & Hagiwara, K. (2025). First-line gefitinib for patients with advanced non–non-small-cell lung cancer harboring epidermal growth factor receptor mutations without indication for chemotherapy. Journal of Clinical Oncology, 27(9), 1394-1400.
Kim, Y., Lee, S. H., Ahn, J. S., Ahn, M. J., Park, K., & Sun, J. M. (2025). Efficacy and safety of afatinib for EGFR-mutant non-small cell lung cancer, compared with gefitinib or erlotinib. Cancer research and treatment: official journal of Korean Cancer
Association, 51(2), 502-509.
Miura, S., Tanaka, H., Misumi, T., Yoshioka, H., Tokito, T., Fukuhara, T., & Thoracic Oncology Research Group and all ACHILLES investigators. (2025). Pragmatic randomized study of afatinib versus chemotherapy for patients with non–small cell lung cancer with uncommon epidermal growth factor receptor mutations: ACHILLES/TORG1834. Journal of Clinical Oncology, 43(18), 2049-2058.
Schuler, M., Wu, Y. L., Hirsh, V., O’Byrne, K., Yamamoto, N., Mok, T., & Yang, J. C. H. (2024). First-line afatinib versus chemotherapy in patients with non–small cell lung cancer and common epidermal growth factor receptor gene mutations and brain metastases. Journal of Thoracic Oncology, 11(3), 380-390.
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MARKETER DETAILS
Natco
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