Afanat 30mg Tablet

Afanat 30mg Tablet

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Salt Composition: Afatinib

Expiry Date: 01/2028

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About The Product

Lung Cancer

The active component of Afanat 30mg Tablet is afatinib dimaleate. Patients with non-small cell lung cancer (NSCLC) whose tumors include specific abnormal epidermal growth factor receptor (EGFR) genes, as well as those with metastatic, squamous NSCLC that progresses following platinum-based chemotherapy, are treated with this anticancer medication.

Reference

Cheema, P. K., Thawer, A., Leake, J., Cheng, S.

Y., Khanna, S., & Charles Victor, J. (2024).

Multi-disciplinary proactive follow-up algorithm for patients with advanced NSCLC receiving afatinib. Supportive Care in Cancer, 27(3), 1029-1039.

Harvey, R. D., Adams, V.

R., Beardslee, T., & Medina, P. (2020).

Afatinib for the treatment of EGFR mutation-positive NSCLC: A review of clinical findings. Journal of Oncology Pharmacy Practice, 26(6), 1461-1474.

Jin, H., Liang, P., Hou, J., Li, B., Wang, P., & He, X. (2023).The Efficacy and Safety of Afatinib in Non‐Small Cell Lung Cancer Patients with Brain Metastasis: A Meta‐Analysis.

Journal of Oncology, (1), 5493725. Lee, C.

K., Wu, Y. L., Ding, P.

N., Lord, S. J., Inoue, A., Zhou, C., & Yang, J.

C. H.

(2025). Impact of specific epidermal growth factor receptor (EGFR) mutations and clinical characteristics on outcomes after treatment with EGFR tyrosine kinase inhibitors versus chemotherapy in EGFR-mutant lung cancer: a meta-analysis.

Journal of Clinical Oncology, 33(17), 1958-1965. Wu, S.

G., Yu, C. J., Yang, J.

C. H., & Shih, J.

Y. (2020).

The effectiveness of afatinib in patients with lung adenocarcinoma harboring complex epidermal growth factor receptor mutation. Therapeutic Advances in Medical Oncology, 12.

Uses

Non-small cell lung cancer (NSCLC) and certain mutations of epidermal growth factor receptor (EGFR).

Side Effects

  • Some of the common side effects of the Afanat 30 mg Tablet are: Infection Headache, Fever Loss of appetite Rash High blood pressure Hair loss lack of sleep.
  • Vomiting Indigestion Nausea Constipation

How To Use

  • Afanat 30mg Tablet is taken once a day regularly at the same time each day to increase its effectiveness.
  • It is an oral medication that can be taken with or without food.
  • The capsules should not be chewed, opened, or crushed; they should be swallowed.
  • Afanat 30mg Tablet should be taken as recommended by the doctor.

How It Works

Afanat 30mg Tablet inhibits or binds to the HER2, HER4, and EGFR enzyme receptors.

It stops or slows the spread of cancer by downregulating signaling pathways.

Safety Advice

Alcohol

Taking an Afanat 30 mg tablet while operating machinery may cause confusion or affect one's capacity to drive. The capsule may cause neurological side effects, such as fever or feeling dizzy. Until you feel better, don't drive

Pregnancy

It is not advised to take the Afanat 30 mg Tablet regularly when pregnant; instead, it should be injected after speaking with the doctor. In cases of difficult, life-threatening situations, Afanat 30 mg Tablet can be administered. But it might affect the fetus.

Breast Feeding

Because there is a possibility that the Afanat 30 mg Tablet could be transferred to the developing infant through the mother's breast milk, it is not advised to consume it while nursing. It is widely regarded as dangerous, and there is not enough evidence in the clinical data on its adverse impacts on infants

Driving

Taking an Afanat 30 mg tablet while operating machinery may cause confusion or affect one's capacity to drive. The capsule may cause neurological side effects, such as fever or feeling dizzy. Until you feel better, don't drive.

Kidney

People with kidney issues can use the Afanat 30 mg Tablet after consulting with the doctor. It may harm the kidneys if taken on self-medication. The capsule contains afatinib, which belongs to a rare case of acute kidney injury (AKI)

Liver

People with mild to severe liver illness should not use the Afanat 30 mg tablet. Even so, the enzyme must be regularly monitored. Use caution and alter the dosage.

FAQs

No, Afanat 30mg Tablet is an anti-cancer medication (specifically a kinase inhibitor or targeted therapy drug) used to treat certain types of non-small cell lung cancer.

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