Marketed By
glenmark
Pack of
28
Salt Composition
Afatinib
Storage
Keep in cold place
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1

Afayro 30mg Tablet
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Indication
Lung Cancer, monotherapy
Description
Afayro 30mg tablet is an ant-cancer medication which is a prescription based medication used to treat non small cell lung cancer (NSCLC). It works by blocking the epidermal growth factor (EGFR) which is involved for the growth and multiplication of cancer cells, thereby helping to slow or stop tumor growth. The active ingredient in the medication is Afatinib, which is a salt form used in the tablet.The medication is used alone as it is a monotherapy medication. Patient should take it exactly as prescribed by the doctor, all medical instructions carefully and report any side effects or unusual symptoms promptly.
Indication
Non small cell lung cancer (NSCLC)
Common side effects
Like other medication Afayro 30mg tablet cause various side effects, some may resolve on their own and some need proper medication to relieve the symptoms. Consult the doctor If the symptoms worsen:
● Diarrhea
● Mouth sores
● Acne or skin rash
● Nausea and vomiting
● Fatigue
● Loss of appetite
● Abdominal pain
● Interstitial lung disease (ILD)
● Severe diarrhea or dehydration
● Liver problems
● Eye problems, such as corneal erosion or ulceration
Dosage and administration
Doctor recommend the correct dosage and duration of Afayro 30mg tablet based on the patient's medical condition and response to the treatment. This tablet should be taken with a whole glass of water, do not crush or chew it take it as it is. Never skip or double the dose without consulting the doctor to ensure safety and effectiveness of the treatment.
Mechanism of action
Afayro 30g tablet is a targeted therapy which specifically target on the cancer cells that is most commonly those with mutation in the EGFR (epidermal growth factor receptor). The medication block EGFR mutation gene which is the responsible for the growth of cancer cells in the body. It helps prevent the growth and multiplication of tumor cells in the body.
Safety advice

Alcohol
caution
Alcohol should not be taken while using Afayro 30mg tablet, as it interfere with the treatment outcomes in many patients.

Driving
consult your doctor
Afayro 30mg tablet do not affect the driving but if you experience any of the side effects while using the medication, must consult the doctor instantly.

Pregnancy
unsafe
Pregnant women should avoid using Afayro 30mg tablet because it harm the fetus and cause birth defects. Women who are pregnant and planning to be pregnant should consult the doctor before taking this medication.

Breast Feeding
unsafe
Afayro 30mg tablet should not be taken by breastfeeding women. The drug may pass into breast milk and could potentially harm the nursing infant. Mothers either avoid feeding milk to their child or should consult the doctor before using the medication.

Kidney
caution
Afayro 30mg is not harmful to kidney patient but the doctor should evaluate kidney function before and during treatment to ensure safety.

Liver
consult your doctor
Afayro tablet is safe for liver patient but it is better to consult the doctor before using them to ensure safety and proper monitoring.
FAQs
Afayro 30mg tablet show various side effects such as diarrhea, mouth sores, fatigue, abdominal pain etc. but they are manageable with proper care and regular medical guidance.
Afayro 30mg tablet is a monotherapy, which means it is used alone without combining it with other anti-cancer medications. The doctor will determine the best treatment plan based on the condition.
Afayro 30mg tablet is prescribed for non small cell lung cancer that work to block the epidermal growth factor receptor (EGFR) which is the cause of cancer cell growth in the body.
Patient should not donate blood while taking Afayro 30mg tablet as the medication can be harmful to the recipient. It is important to inform the doctor if you are planning to donate blood.
If you have a history of heart problem then discuss the problem with the healthcare provider also the benefits of Afayro 30mg tablet to avoid complications and enhance the effectiveness of the treatment.
Reference
• Wecker, H., & Waller, C. F. (2018). Afatinib. Small Molecules in Oncology, 199-215.
• Dungo, R. T., & Keating, G. M. (2013). Afatinib: first global approval. Drugs, 73(13), 1503-1515.
• Wind, S., Schnell, D., Ebner, T., Freiwald, M., & Stopfer, P. (2017). Clinical pharmacokinetics and pharmacodynamics of afatinib. Clinical pharmacokinetics, 56(3), 235-250.
• Nelson, V., Ziehr, J., Agulnik, M., & Johnson, M. (2013). Afatinib: emerging next-generation tyrosine kinase inhibitor for NSCLC. OncoTargets and therapy, 135-143.
• Keating, G. M. (2014). Afatinib: a review of its use in the treatment of advanced non-small cell lung cancer. Drugs, 74(2), 207-221.
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