
baraclude 0.5mg Tablet
Salt Composition: Entecavir (0.5 mg)
Expiry Date: 01/2028
Inclusive of all taxes
10 tablet in a Strip
About The Product
Hepatitis B
Entecavir is a white to off-white powder. It is slightly soluble in water (2.4 mg/mL), and the pH of the saturated solution in water is 7.9 at 25° C ± 0.5° C. Baraclude film-coated tablets are for oral administration in strengths of 0.5 mg and 1 mg of entecavir. Baraclude 0.5 mg and 1 mg film-coated tablets contain the following inactive ingredients: lactose monohydrate, microcrystalline cellulose, crospovidone, povidone, and magnesium stearate. The tablet coating contains titanium dioxide, hypromellose, polyethylene glycol 400, polysorbate 80 (0.5 mg tablet only), and iron oxide red (1 mg tablet only). Baraclude Oral Solution is available for oral administration as a ready-to-use solution containing 0.05 mg of entecavir per milliliter. Baraclude Oral Solution contains the following inactive ingredients: maltitol, sodium citrate, citric acid, methylparaben, propylparaben, and orange flavor. Baraclude is a Hepatitis B virus nucleoside analog reverse transcriptase inhibitor, which is indicated for the treatment of chronic hepatitis B virus infection in adults and children, provided at least 2 years of age with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (ALT or AST) or histologically active disease. It is not known that Baraclude is safe for children below 2 years of age. Baraclude will not cure HPV. It may decrease the ability of HPV to multiply.
Description
Entecavir is phosphorylated to the active triphosphate form (ETV-TP) by cellular nucleoside kinases. This was shown in different cell systems including infected hepatoma cell lines but the extent of phosphorylation of entecavir was dependent on cell type.
The triphosphate competes with the natural substrate, deoxyguanosine triphosphate (dGTP), of human HBV polymerase. In vitro studies on the mechanism of action indicated that the three enzymatic activities of the viral polymerase were inhibited 1) priming activity, 2) reverse transcriptase activity resulting in first-strand DNA synthesis, and 3)
DNA-dependent DNA polymerase activity resulting in second-strand DNA synthesis.
Side Effects
- Following are the possible side effects that can occur during your treatment with baraclude 0.5mg Tablet.
- Contact your medical practitioner immediately if any of the above-mentioned side effects appear.
- Dizziness Unusual sweating Skin rash Itching Taste change Blurred vision Confusion Fever Chills Depression
How To Use
Baraclude is used in the treatment of chronic Hepatitis B virus infection in adults and children provided at least 2 years of age.
Safety Advice
Missed Doses
- It is advisable not to miss a dose.
- If you miss a scheduled dose of baraclude 0.5mg Tablet tablets, contact your doctor immediately.
FAQs
Ans-1 Baraclude is a prescription medicine used in the treatment of chronic Hepatitis B virus infection in adults and children (at least 2 years of age).
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