Bdparp 150mg Tablet

Bdparp 150mg Tablet

Prescription requiredRx Required

Salt Composition: Olaparib

Expiry Date: 01/2028

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28 Tablets in Bottle

About The Product

Ovarian Cancer, Breast Cancer

Olaparib, an element of the antiviral medication class polyadenosine diphosphate-ribose polymerase (PARP), is found in the Bdparp 150mg. Cells proliferate uncontrollably in cancer. This tablet can be taken either by itself or in combination with other anticancer drugs to treat pancreatic and prostate cancer.

Uses

Prostate cancer

Pancreatic cancer, Breast cancer, Ovarian cancer


Side Effects

Undesired symptoms or responses vary from person to person as the human body reacts differently to the Bdparp 100mg tablet. Still, they typically resolve naturally within a few days as the body adjusts to the medicine, requiring no medical attention. In case these symptoms don't go away and you face severe side effects, then immediately consult your doctor or medical team. Some of the common side effects of the Bdparp 100mg tablet are:

Headache,

Fever

Loss of appetite

Pain in the eyes

Blurred vision

High blood pressure

red and itchy eyes

lack of sleep.

Vomiting

Indigestion

Nausea diarrhea, or constipation

blood in the urine or a burning sensation while urinating

hair loss


How To Use

  • Bdparp 100mg tablets should never be used for self-medication; instead, they should always be used as directed by a physician.
  • As prescribed by the physician, it can be taken with or without food.
  • Your doctor will decide on the amount and timing of the Bdparp 100mg based on your condition and other factors.
  • For best results, the Bdparp 100mg tablet should be swallowed rather than chewed, opened, or crushed.
  • It is an oral drug that should be taken as prescribed by the physician at the same time each day.

How It Works

Bdparp 100mg tablet works by blocking the repair mechanism of DNA, as a result growth of cancer cells stops. The tablet inhibits PARP (poly-ADP-Ribose Polymerases), which belongs to the family of proteins that play an important role in genomic stability, DNA repair, and cellular stress responses.

The enzymes repair the single-strand DNA breaks (SSBs). Bdparp 100mg tablet inhibits the working of PARP enzymes, which hinders the growth and development of cancer cells.

Safety Advice

Alcohol
Drinking too much alcohol could damage a person's immunity and liver function. Alcohol consumption can cause dizziness, confusion, tiredness, and cognitive impairment, so it is advised not to consume alcohol while taking the Bdparp 150mg tablet.
Pregnancy
It is not advised to take the Bdparp 150mg tablet when pregnant because it affects the fetus. This is not for use in pregnant women.
Breast Feeding
Because the Bdparp 150 mg tablet may be transferred to the developing infant through breast milk, it is not advised to take it while nursing. It is widely regarded as dangerous, and there is not enough evidence in the clinical data on its adverse impacts on infants.
Driving
Taking a Bdparp 150 mg tablet while operating machinery may cause confusion or impair one's driving capacity. The capsule may cause neurological side effects, such as fever or feeling dizzy. Until you feel better, don't drive.
Kidney
People with kidney issues can use the Bdparp 150 mg tablet after consulting the doctor. It may harm the kidneys if taken as self-medication.
Liver
People with severe liver illness should not use the Bdparp 150 mg tablet. Whereas people with mild liver disease can use this solution, but it must be regularly monitored. Use caution and alter the dosage of the Bdparp 150 mg tablet as advised by your doctor.

FAQs

A person with low white blood cells is advised to consult the doctor first before taking the Bdparp 150 mg tablet, as this drug can also cause neutropenia.

Reference

Audeh, M. W., Carmichael, J., Penson, R.

T., Friedlander, M., Powell, B., Bell-McGuinn, K. M., & Tutt, A.

(2020). Oral poly (ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial.

The Lancet, 376(9737), 245-251. Guo, X.

X., Wu, H. L., Shi, H.

Y., Su, L., & Zhang, X. (2024).

The efficacy and safety of olaparib in the treatment of cancers: a meta-analysis of randomized controlled trials. Cancer Management and Research, 2553-2562.

Tutt, A., Robson, M., Garber, J. E., Domchek, S.

M., Audeh, M. W., Weitzel, J.

N. & Carmichael, J. (2020).

Oral poly (ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial. The Lancet, 376(9737), 235-244. van der Noll, R., Jager, A., Ang, J.

E., Marchetti, S., Mergui-Roelvink, M. W., de Bono, J.

S., & Schellens, J. H.

(2020). Phase I study of intermittent olaparib capsule or tablet dosing in combination with carboplatin and paclitaxel (part 2).

Investigational New Drugs, 38(4), 1096-1107. Yamamoto, N., Nokihara, H., Yamada, Y., Goto, Y., Tanioka, M., Shibata, T.,& Tamura, T.

(2020). A Phase I, dose‐finding and pharmacokinetic study of olaparib (AZD2281) in Japanese patients with advanced solid tumors.

Cancer science, 103(3), 504-509.

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