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Bracaloc 150mg Tablet

Bracaloc 150mg Tablet

Prescription requiredRx Required

Salt Composition: Olaparib

Expiry Date: 01/2028

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30 Tablets in Bottle

About The Product

Ovarian Cancer, Breast Cancer


Description

Bracaloc 150mg tablet is a targeted based medication. The medicine is used in the treatment of breast cancer and ovarian cancer as wellIts active ingredient is Olaparib which belongs to the class group of PARP ( Poly ADP- Ribose polymerase inhibitor).

This works by blocking PARP enzyme which is the major cause of growth of cancer cell in the body, preventing them from repairing damaged DNA that leads to cancer cell death and help slow down the disease progression with specific genetic mutation. By specifically acting on cancer cell mechanism, the medicine supports better clinical outcomes and a more precise cancer therapy.

This medicine is not recommended to children under the age of 18.

Indication

Breast cancer and ovarian cancer

Common Side Effects

  • All drugs can cause some side effects, some of them may show acute and some may cause severe symptoms.
  • Consult the doctor if any if these symptoms persist: ● Muscle cramps ● Confusion, visual disturbances, seizures, and headache ● Breathlessness ● Swelling of feet ● Changes in heartbeat ● High blood pressure ● Pneumonia ● Loss of appetite ● Sensitivity, tingling and burning sensation of the skin ● Nausea, vomiting, and diarrhea ● Mouth ulcers ● Constipation

Dosage And Duration

  • Bracaloc 150mg tablet should be taken with or without food.
  • It should be taken under orally with a whole glass of water.
  • Do not crush or chew the tablet as it may affect the medicine is absorbed in the body.
  • Consistency is key.
  • Try to take it regularly at the same time everyday to increase the effectiveness of the medicine.
  • Taking the injection in the wrong way may increase the side effects which interrupt the treatment.

Mechanism Of Action

Breast and ovarian cancer develops because of genetic mutation which is caused by the gene mutation. Bracaloc 150mg tablet specifically inhibiting the PARP enzyme in cancer cells, which is the major cause of cancer growth in the body.

The medicine also helps to slow down the disease progression and provides patients a less toxic option.

Safety Advice

Alcohol
Taking Bracaloc 150mg tablet with alcohol is may be dangerous to the patient health but consult the doctor before taking the medication.
Driving
Bracaloc tablet may not cause dizziness or sleepiness but patient may still experience some side effects. It is important to monitor the response of medication and report any unusual symptoms to the doctor.
Pregnancy
Bracaloc 150mg tablet is not recommended to pregnant and breastfeeding women as it may affect the fetus or newborn. Take guidance from a healthcare expert to ensure safety and precautions.
Kidney
Kidney patients should take precautions while using the medication as dose adjustment and doctor's prescription is much needed.
Liver
Bracaloc 150mg tablet may interrupt with liver function. Patients with liver disease should consult the doctor before using it.

Reference

• Bochum, S., Berger, S., & Martens, U. M.

(2018). Olaparib.

Small molecules in oncology, 217-233. • Deeks, E. D.

(2015). Olaparib: first global approval.

Drugs, 75(2), 231-240. • Robson, M., Im, S. A., Senkus, E., Xu, B., Domchek, S.

M., Masuda, N., ... & Conte, P. (2017).

Olaparib for metastatic breast cancer in patients with a germline BRCA mutation. New England Journal of Medicine, 377(6), 523-533. • de Bono, J., Mateo, J., Fizazi, K., Saad, F., Shore, N., Sandhu, S., ... & Hussain, M.

(2020). Olaparib for metastatic castration-resistant prostate cancer.

New England Journal of Medicine, 382(22), 2091-2102. • Mateo, J., Carreira, S., Sandhu, S., Miranda, S., Mossop, H., Perez-Lopez, R., ... & de Bono, J. S.

(2015). DNA-repair defects and olaparib in metastatic prostate cancer.

New England Journal of Medicine, 373(18), 1697-1708.

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