Calutide 50mg Tablet
Prescription Required
Marketed By
cipla
Pack of
10 tablet
Salt Composition
Bicalutamide
Storage
Keep in cold place
₹335₹462.53
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Calutide 50mg Tablet
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Overview
Calutide 50mg Tablet is an anticancer drug used for the treatment of advanced prostate cancer. Calutide 50mg Tablet can also be used to treat other diseases, as a doctor prescribes. This drug blocks the male sex hormone testosterone. Further, it slows down the multiplication of cancer cells. This drug is given with a Luteinizing Hormone-Releasing Hormone (LHRH) analog after surgical removal of testicles.
Indication
Prostate Cancer
Description
Calutide 50mg tablet is a prescription-based anticancer drug with an active ingredient called Bicalutamide. The doctor prescribes this drug for the treatment of advanced prostate cancer. Calutide 50mg tablet is given as androgen deprivation therapy, a combination of radiation and hormonal therapy. Androgen deprivation therapy drops down the levels of testosterone. The sensitivity of prostate cancer depends on androgen. Hence, the Calutide 50mg tablet aims to counteract the effect of androgen. It is recommended to take proper consultation with your doctor before taking it. Your doctor will decide the dosage and duration of taking this medicine. Taking it in the wrong way or overdosing can cause severe side effects. It is advised to use reliable methods of birth control and contraceptive pills to delay pregnancy while under treatment with Calutide 50mg tablet. Discuss with your healthcare expert the risks and benefits of taking this medicine if you want to conceive in the future.
Side Effects
Like other anticancer medicines, the Calutide 50mg Tablet has mild to severe side effects. These are undesired symptoms observed in the body after taking this tablet. Usually, they disappear with time as the body adjusts to the medicine. These adverse effects don't need special medical attention, but if you observe them continually, talk to your medical expert. Some of them are listed below:
Common side effects:
Anemia
Nausea & Vomiting
Constipation
Body pain
Rashes and skin allergy
Heavy urination during the night
Low sex drive
Loss in appetite
Edema
Weakness & dizziness
Breathlessness
Hair loss
Hot flushes
Severe side effects:
Heart problem
blood in urine
Difficulty in urine
Increased blood sugar level
Increase in liver enzyme level
How To Use
Calutide 50mg Tablet is a prescription-based anticancer drug that should be administered orally. It is advised to take this tablet after consulting your healthcare expert.
How It Works
Calutide 50mg Tablet belongs to the drug class of non-steroidal anti-androgens. This medicine binds to cytosol androgen receptors and inhibits the effect of androgen hormones. It blocks the interaction of androgen receptors with testosterone and dihydrotestosterone hormones. In such a way, it shrinks the tumors and slows down the multiplication of the cancer cells.
Safety Advice

Alcohol
consult your doctor
The interaction of alcohol with this drug is still unknown. It is advisable not to consume alcohol while taking Calutide 50mg Tablet. Consult your doctor for further information.

Pregnancy
consult your doctor
Calutide 50mg Tablet may be considered unsafe during pregnancy. Please consult your doctor in such a condition.

Breast Feeding
consult your doctor
Calutide 50mg Tablet is probably not safe if you're breastfeeding. Kindly consult your doctor.

Driving
unsafe
It is advisable not to drive or operate heavy machinery as you may feel dizzy after taking Calutide 50mg Tablet.

Kidney
safe if prescribed
Share your medical history with your healthcare expert in case of kidney disease before taking Calutide 50mg Tablet.

Liver
safe if prescribed
Inform your doctor before starting Calutide 50mg Tablet if you have liver disease to avoid any serious side effects.
Missed Doses
It is advised not to miss any scheduled dosage of Calutide 50mg Tablet. In case you miss a dose, consult your doctor immediately.
Don't overdose to compensate for the missed one. Contact your doctor or any healthcare provider and seek medical attention immediately in such cases.
Quick Tips
Using Calutide 50mg Tablet causes light sensitivity. Use sunscreen before exposing to direct sunlight.
It is recommended to inform your doctor if you take any prescribed and non-prescribed medications, nutritional or vitamin supplements, or herbal products. These drugs can interact with Calutide 50mg Tablet and may result in some severe side effects.
Your healthcare provider will decide how much you take and how often you need Calutide 50mg Tablet. You are advised to follow the prescription strictly.
Your healthcare expert must measure your blood sugar & pressure, and liver function tests at regular intervals. Taking the Calutide 50mg Tablet can cause fluctuations in their levels.
FAQs
Calutide 50mg tablet is prescribed with another medication (gonadotropin-releasing hormone (GnRH) agonists) for the treatment of advanced prostate cancer, which has spread to other parts of the body. Calutide Tablet is also used for treating PCOS, but it is not approved for use in that.
The most common side effect of using Calutide 50mg tablet is anemia. Consult with your medical professional if you experience any side effects such as blood in urine, loss of appetite, shortness of breath, abdominal pain, dark urine, skin rashes, and difficulty in urination.
No, Calutide 50mg tablet is not chemotherapy. It is an anti-androgen medicine that blocks the actions of male sex hormones. By blocking, it lowers the growth and multiplication of cancer cells.
Yes, Taking Calutide 50mg tablet may cause infertility in males. Men should not become fathers or donate sperm during or for 3 months after the last dose of Calutide Tablet. Consult your physician on prior if you are planning to conceive in the future.
Using Calutide 50mg tablet causes light sensitivity. It is advised to avoid direct exposure to sunlight, sunbeds, sunlamps, and tanning. Use sunscreen before exposing to direct sunlight.
Reference
Boccardo, F., Rubagotti, A., Battaglia, M., Di Tonno, P., Selvaggi, F. P., Conti, G. & Montefiore, F. (2025). Evaluation of tamoxifen and anastrozole in the prevention of gynecomastia and breast pain induced by bicalutamide monotherapy of prostate cancer. Journal of Clinical Oncology, 23(4), 808-815.
Boccardo, F., Rubagotti, A., Conti, G., Potenzoni, D., Manganelli, A., & Monaco, D. D. (2024). Exploratory study of drug plasma levels during bicalutamide 150 mg therapy co-administered with tamoxifen or anastrozole for prophylaxis of gynecomastia and breast pain in men with prostate cancer. Cancer chemotherapy and pharmacology, 56(4), 415-420.
Kotake, T., Usami, M., Isaka, S., Shimazaki, J., Nakano, E., Okuyama, A., & Tsukagoshi, S. (2025). Clinical early phase II study of bicalutamide (Casodex) in patients with prostatic cancer. Hinyokika Kiyo. Acta Urologica Japonica, 42(2), 157-168.
Kotake, T., Usami, M., Isaka, S., Shimazaki, J., Oishi, K., Yoshida, O., & Taguchi, T. (2023). Phase I study of bicalutamide (Casodex), a nonsteroidal antiandrogen in patients with prostatic cancer. Hinyokika Kiyo. Acta Urologica Japonica, 42(2), 143-153.
Kunath, F., Grobe, H. R., Ruecker, G., Motschall, E., Antes, G., Dahm, P. & Meerpohl, J. J. (2024). Non‐steroidal antiandrogen monotherapy compared with luteinising hormone–releasing hormone agonists or surgical castration monotherapy for advanced prostate cancer. Cochrane Database of Systematic Reviews, (6).
Saltzstein, D., Sieber, P., Morris, T., & Gallo, J. (2025). Prevention and management of bicalutamide-induced gynecomastia and breast pain: randomized endocrinologic and clinical studies with tamoxifen and anastrozole. Prostate cancer and prostatic diseases, 8(1), 75-83.
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