Casodex 50mg Tablet
Rx RequiredSalt Composition: Bicalutamide
Expiry Date: 01/2028
Price on Request
Inclusive of all taxes
28 tablet
About The Product
Prostate Cancer
Casodex 50mg tablet is an anticancer drug used for the treatment of advanced prostate cancer. This tablet can also be used to treat another disease, as per the doctor's prescription. This drug blocks the male sex hormone testosterone. Further, it slows down the multiplication of cancer cells. Casodex tablet is given with a Luteinizing Hormone-Releasing Hormone (LHRH) analog or after surgical removal of testicles.
Description
Casodex 50mg tablet is a prescription-based anticancer drug with an active ingredient called Bicalutamide. The doctor prescribes this drug for the treatment of advanced prostate cancer.
This tablet is given as androgen deprivation therapy, a combination of radiation and hormonal therapy. Androgen deprivation therapy drops down the levels of testosterone.
The sensitivity of prostate cancer depends on androgen. Hence, the Casodex tablet aims to counteract the effect of androgen.
It is recommended to take proper consultation with your doctor before taking it. Your doctor will decide the dosage and duration of taking this medicine.
Taking it in the wrong way or overdosing can cause severe side effects. It is advised to use reliable methods of birth control and contraceptive pills to delay pregnancy while under treatment with Casodex 50mg tablet.
Discuss with your healthcare expert the risks and benefits of taking this medicine if you want to conceive in the future.
Side Effects
- Like other anticancer medicines, the Casodex 50mg tablet has mild to severe side effects.
- These are undesired symptoms observed in the body after taking this tablet.
- Usually, they disappear with time as the body adjusts to the medicine.
- These side effects don't need special medical attention, but if you observe them continually, talk to your medical expert.
- Some of them are listed below: Common side effects: Anemia Diarrhea Anxiety Constipation Low sex drive Loss in appetite Breathlessness Fall and fractures Body and back pain Nausea & Vomiting Weakness & dizziness Rashes and skin allergy Heavy urination during the night Severe side effects: Heart problem blood in urine Difficulty in urine Rare disorders with swelling in the brain Increased blood sugar and liver enzyme level
How To Use
- Casodex 50mg Tablet is a prescription-based anticancer drug that should be administered orally.
- It is advised to take this tablet after consulting your healthcare expert.
How It Works
Casodex 50mg tablet belongs to the drug class of non-steroidal anti-androgens. This medicine binds to cytosol androgen receptors and inhibits the effect of androgen hormones.
It blocks the interaction of androgen receptors with testosterone and dihydrotestosterone hormones. In such a way, it shrinks the tumors and slows down the multiplication of the cancer cells.
Safety Advice
Missed Doses
- It is advised not to miss any scheduled dosage of Casodex 50mg Tablet.
- In case you miss a dose, consult your doctor immediately.
- Don't overdose to compensate for the missed one.
- Contact your doctor or any healthcare provider and seek medical attention immediately in such cases.
Quick Tips
Using Casodex 50mg Tablet makes skin light sensitive and dry. Use high SPF sunscreen before exposing to direct sunlight.
Your healthcare expert must measure your blood sugar & pressure and liver function tests at regular intervals. Taking the Casodex 50mg Tablet can cause fluctuations in their levels.
It is recommended to inform your doctor if you take any prescribed and non-prescribed medications, nutritional or vitamin supplements, or herbal products. These drugs can interact with Casodex 50mg Tablet and may result in some severe side effects.
FAQs
Casodex 50mg tablet is prescribed with another medication (gonadotropin-releasing hormone (GnRH) agonists) for the treatment of advanced prostate cancer, which has spread to other parts of the body.
Casodex 50mg Tablet is also used for treating PCOS, but it is not approved for use in that.
Reference
Shiner, A., Sperandio, R. C., Naimi, M., & Emmenegger, U.
(2024). Prostate cancer liver metastasis: an ominous metastatic site in need of distinct management strategies.
Journal of Clinical Medicine, 13(3), 734. Sun, Y., Xu, T., Zhu, S., & Xu, H.
(2024). Characteristics of adverse drug reactions induced by flutamide and bicalutamide: a real-world pharmacovigilance study using FAERS.
Expert Opinion on Drug Safety, 23(3), 305-311. Iversen, P., Tveter, K., Varenhorst, E., & Scandinavian Casodex Cooperative Group.
(2024). Randomised study of Casodex 50 mg monotherapy vs orchidectomy in the treatment of metastatic prostate cancer.
Scandinavian Journal of Urology and Nephrology, 30(2), 93-98. Kotake, T., Usami, M., Isaka, S., Shimazaki, J., Oishi, K., Yoshida, O. & Taguchi, T.
(2025). Phase I study of bicalutamide (Casodex), a nonsteroidal antiandrogen in patients with prostatic cancer.
Hinyokika Kiyo. Acta Urologica Japonica, 42(2), 143-153.
Kaisary, A. V., Tyrrell, C.
J., Beacock, C., Lunglmayr, G., & Debruyne, F. (2023).
A randomised comparison of monotherapy with Casodex 50 mg daily and castration in the treatment of metastatic prostate carcinoma. European urology, 28(3), 215-222.
Tyrrell, C. J., Iversen, P., Tammela, T., Anderson, J., Björk, T., Kaisary, A.
V., & Morris, T. (2024).
Tolerability, efficacy, and pharmacokinetics of bicalutamide 300 mg, 450 mg, or 600 mg as monotherapy for patients with locally advanced or metastatic prostate cancer, compared with castration. BJU international, 98(3), 563-572.
Medical Disclaimer
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