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Casodex 50mg Tablet

Prescription Required

Marketed By

astra zeneca

Pack of

28 tablet

Salt Composition

Bicalutamide

Storage

Keep in cold place

580635.63

8.75% Off

Inclusive of all taxes

1

Casodex 50mg Tablet

Casodex 50mg Tablet

580635.63
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Overview

Casodex 50mg tablet is an anticancer drug used for the treatment of advanced prostate cancer. This tablet can also be used to treat another disease, as per the doctor's prescription. This drug blocks the male sex hormone testosterone. Further, it slows down the multiplication of cancer cells. Casodex tablet is given with a Luteinizing Hormone-Releasing Hormone (LHRH) analog or after surgical removal of testicles.

Indication

Prostate Cancer

Description

Casodex 50mg tablet is a prescription-based anticancer drug with an active ingredient called Bicalutamide. The doctor prescribes this drug for the treatment of advanced prostate cancer. This tablet is given as androgen deprivation therapy, a combination of radiation and hormonal therapy. Androgen deprivation therapy drops down the levels of testosterone. The sensitivity of prostate cancer depends on androgen. Hence, the Casodex tablet aims to counteract the effect of androgen. It is recommended to take proper consultation with your doctor before taking it. Your doctor will decide the dosage and duration of taking this medicine. Taking it in the wrong way or overdosing can cause severe side effects. It is advised to use reliable methods of birth control and contraceptive pills to delay pregnancy while under treatment with Casodex 50mg tablet. Discuss with your healthcare expert the risks and benefits of taking this medicine if you want to conceive in the future.

Side Effects

Like other anticancer medicines, the Casodex 50mg tablet has mild to severe side effects. These are undesired symptoms observed in the body after taking this tablet. Usually, they disappear with time as the body adjusts to the medicine. These side effects don't need special medical attention, but if you observe them continually, talk to your medical expert. Some of them are listed below:


Common side effects:
Anemia
Diarrhea
Anxiety
Constipation
Low sex drive
Loss in appetite
Breathlessness
Fall and fractures
Body and back pain
Nausea & Vomiting
Weakness & dizziness
Rashes and skin allergy
Heavy urination during the night


Severe side effects:
Heart problem
blood in urine
Difficulty in urine
Rare disorders with swelling in the brain
Increased blood sugar and liver enzyme level

How To Use

Casodex 50mg Tablet is a prescription-based anticancer drug that should be administered orally. It is advised to take this tablet after consulting your healthcare expert.


How It Works

Casodex 50mg tablet belongs to the drug class of non-steroidal anti-androgens. This medicine binds to cytosol androgen receptors and inhibits the effect of androgen hormones. It blocks the interaction of androgen receptors with testosterone and dihydrotestosterone hormones. In such a way, it shrinks the tumors and slows down the multiplication of the cancer cells.


Safety Advice

Alcohol

Alcohol

consult your doctor

The interaction of alcohol with this drug is still unknown. It is advisable not to consume alcohol while taking Casodex 50mg Tablet. Consult your doctor for further information.

Pregnancy

Pregnancy

consult your doctor

Casodex 50mg Tablet may be considered unsafe during pregnancy. Please consult your doctor in such a condition.

Breast Feeding

Breast Feeding

consult your doctor

Casodex 50mg Tablet is probably not safe if you're breastfeeding. Kindly consult your doctor.

Driving

Driving

unsafe

It is advisable not to drive or operate heavy machinery as you may feel dizzy after taking Casodex 50mg Tablet.

Kidney

Kidney

safe if prescribed

Share your medical history with your healthcare expert in case of kidney disease before taking Casodex 50mg Tablet.

Liver

Liver

safe if prescribed

Inform your doctor before starting Casodex 50mg Tablet if you have liver disease to avoid any serious side effects.

Missed Doses

It is advised not to miss any scheduled dosage of Casodex 50mg Tablet. In case you miss a dose, consult your doctor immediately.


Don't overdose to compensate for the missed one. Contact your doctor or any healthcare provider and seek medical attention immediately in such cases.

Quick Tips

Using Casodex 50mg Tablet makes skin light sensitive and dry. Use high SPF sunscreen before exposing to direct sunlight.


Your healthcare expert must measure your blood sugar & pressure and liver function tests at regular intervals. Taking the Casodex 50mg Tablet can cause fluctuations in their levels.


It is recommended to inform your doctor if you take any prescribed and non-prescribed medications, nutritional or vitamin supplements, or herbal products. These drugs can interact with Casodex 50mg Tablet and may result in some severe side effects.

FAQs

Which disease is treatable with a Casodex 50mg tablet?

Casodex 50mg tablet is prescribed with another medication (gonadotropin-releasing hormone (GnRH) agonists) for the treatment of advanced prostate cancer, which has spread to other parts of the body. Casodex 50mg Tablet is also used for treating PCOS, but it is not approved for use in that.

Can we manage side effects that are observed after taking Casodex 50mg tablet?

The most common side effect after taking Casodex 50mg Tablet is anemia. Consult with your medical professional if you experience any side effects such as blood in urine, loss of appetite, shortness of breath, abdominal pain, dark urine, skin rashes, and difficulty in urination.

Is Casodex 50mg tablet chemotherapy drug?

No, the Casodex 50mg tablet is not a chemotherapy drug. It is an anti-androgen medicine that blocks the actions of male sex hormones. By blocking, it lowers the growth and multiplication of cancer cells.

Does taking Casodex 50mg make person infertile?

Yes, Taking Casodex 50mg tablet may cause infertility in males. Men should not become fathers or donate sperm during or for 3 months after the last dose of Casodex 50mg Tablet. Consult your physician on prior if you are planning to conceive in the future.

What precautions should I take while taking Casodex 50mg Tablet?

Using Casodex 50mg tablet makes skin light sensitive, and dry. It is advised to avoid direct exposure to sunlight, sunbeds, sunlamps, and tanning. Use high SPF sunscreen before exposing to direct sunlight.

Reference

Shiner, A., Sperandio, R. C., Naimi, M., & Emmenegger, U. (2024). Prostate cancer liver metastasis: an ominous metastatic site in need of distinct management strategies. Journal of Clinical Medicine, 13(3), 734.
Sun, Y., Xu, T., Zhu, S., & Xu, H. (2024). Characteristics of adverse drug reactions induced by flutamide and bicalutamide: a real-world pharmacovigilance study using FAERS. Expert Opinion on Drug Safety, 23(3), 305-311.
Iversen, P., Tveter, K., Varenhorst, E., & Scandinavian Casodex Cooperative Group. (2024). Randomised study of Casodex 50 mg monotherapy vs orchidectomy in the treatment of metastatic prostate cancer. Scandinavian Journal of Urology and Nephrology, 30(2), 93-98.
Kotake, T., Usami, M., Isaka, S., Shimazaki, J., Oishi, K., Yoshida, O. & Taguchi, T. (2025). Phase I study of bicalutamide (Casodex), a nonsteroidal antiandrogen in patients with prostatic cancer. Hinyokika Kiyo. Acta Urologica Japonica, 42(2), 143-153.
Kaisary, A. V., Tyrrell, C. J., Beacock, C., Lunglmayr, G., & Debruyne, F. (2023). A randomised comparison of monotherapy with Casodex 50 mg daily and castration in the treatment of metastatic prostate carcinoma. European urology, 28(3), 215-222.
Tyrrell, C. J., Iversen, P., Tammela, T., Anderson, J., Björk, T., Kaisary, A. V., & Morris, T. (2024). Tolerability, efficacy, and pharmacokinetics of bicalutamide 300 mg, 450 mg, or 600 mg as monotherapy for patients with locally advanced or metastatic prostate cancer, compared with castration. BJU international, 98(3), 563-572.

MARKETER DETAILS

astra zeneca

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