Dasamed 50mg Tablet
Rx RequiredSalt Composition: Dasatinib
Expiry Date: 01/2028
Buy at $52.41
Inclusive of all taxes
60 Tablets in Bottle
About The Product
Chronic Myeloid Leukemia
Description
Dasamed 50mg Tablet is an allopathic medicine prescribed by the doctor to treat various phrases of Chronic Myeloid Leukemia (CML) as well as Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ALL), especially when other therapies failed. Dasamed 50mg Tablet contains 50mg of Dasatinib that binds to the specific abnormal tyrosine kinase protein that is responsible for cancer progression signaling.
Blockage of such abnormal protein lead to reduction in cancer growth and proliferation.
Indication
Chronic Myeloid Leukemia (CML) as well as Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ALL)
Dosage And Administration
- Dasamed 50mg Tablet is taken orally once a day with or without food.
- This is the usual starting dosage for adults but can vary later based on the cancer stage and its progression.
- Tablets should be consumed whole as it is without breaking, chewing or biting to maintain their efficacy.
- For exact dosage, contact your doctor.
- Don't miss the dosage and remain consistent about medication.
Mechanism Of Action
Dasamed 50mg Tablet contains Dasatinib salt that primarily inhibits abnormal BCR-ABL tyrosine kinase activity that is responsible for cancer cell growth and proliferation. It binds to the mutated BCR-ABL tyrosine kinase that inhibits further signaling of cancer progression.
It also blocks other such families such as SRC family kinases that is responsible for cancer progression. Blockage of BCR-ABL tyrosine kinase and SRC family kinases leads to reduction in cancer progression.
Faqs
Dasamed 50mg Tablet is used to treat various phrases of Chronic Myeloid Leukemia (CML) as well as Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ALL), especially when other therapies failed.
References
• Lindauer, M., & Hochhaus, A. (2009).
Dasatinib. Small molecules in oncology, 83-102. • Aguilera, D.
G., & Tsimberidou, A. M.
(2009). Dasatinib in chronic myeloid leukemia: a review.
Therapeutics and Clinical Risk Management, 281-289. • Wang, M., & Chang, A. Y.
C. (2018).
Molecular mechanism of action and potential biomarkers of growth inhibition of synergistic combination of afatinib and dasatinib against gefitinib-resistant non-small cell lung cancer cells. Oncotarget, 9(23), 16533. • Caldemeyer, L., Dugan, M., Edwards, J., & Akard, L.
(2016). Long-term side effects of tyrosine kinase inhibitors in chronic myeloid leukemia.
Current hematologic malignancy reports, 11(2), 71-79.
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