Mfd. by :- Boehringer Ingelheim (Fulfilled By : Magicine Pharma)
Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.
Brand Name:- Giotrif
Generic Name:- Afatinib
Manufacturer:- Boehringer Ingelheim
Dosage Form:- Tablets
Strength:- 20mg
Composition:- Afatinib
Packaging:- 30 tablets
Indication:- Non-small cell lung cancer
Storage:- Store medicine at room temperature.
Giotrif (Afatinib) medicine helps to treat and prevent the growth of metastatic non-small cell lung cancer. Afatinib 30mg Tablet is an anticancer medicine. Afatinib 30mg Tablet belongs to a group of medicine called a tyrosine kinase inhibitor which blocks proteins that promote the growth of cancer cells. It comes in the form of tablets and is to be taken on an empty stomach. Non-small cell lung cancer (NSCLC) results from the uncontrolled growth of cancer cells in the lung. EGFR is a protein found on the surface of cancer cells that controls the development of cancerous cells. Afatinib 30mg Tablet is not recommended to use if you are allergic to it. Dose administration is decided by your doctor.
Afatinib 30mg Tablet is a powerful and selective, irreversible ErbB family blocker. It irreversibly blocks signals from all homo heterodimers formed by the ErbB family members EGFR (ErbB1), ErbB2, ErbB3, and ErbB4. The effect of Afatinib 30mg Tablet can be observed within 2 to 5 hours after oral administration.
Afatinib 30mg Tablet may cause some serious and unwanted side effects. Which requires immediate medical attention otherwise it can also lead to higher risk. Do not forget to discuss the risk and benefits of this medication with your doctor.
Mouth sore
Vomiting
Decreased appetite
Dry skin
Infection
Runny or stuffy nose
Nausea
Skin rash
Diarrhea
Muscle pain
Nose bleeds
Muscle pain
Change in taste
Stomach pain
Weight loss
Swelling around nails
Acne
Blurred vision
Severe diarrhea
Skin reactions
Liver problems
Tiredness
Yellowing of skin
Pain in the upper abdomen
Dark or brown urine
Heart problems
Shortness of breath
Irregular heartbeat
Sudden weight gain
Swelling of feet and legs
Lung problems
Trouble in breathing
Cough
Fever
Note- If any of these side effects occur, please contact your doctor
Use Afatinib 30mg Tablet as prescribed by your doctor. Do not take this medicine in the wrong way and make sure to take this medication according to your dosing schedule.
In case you missed a dose, immediately contact your doctor. Do not use extra medicine to double up for the missed dose.
Emergency medical treatment is required. Please contact your medical advisor in case of an overdose.
Afatinib 30mg Tablet is prescribed to use in the treatment of non-small cell lung cancer. Take this medicine orally once a day. This medicine should be taken at least 1 hour before or 3 hours after the meals. Do not stop the use of this medicine without taking permission from your doctor. Take this medicine as prescribed by your medical advisor. Try not to miss your regular dosing schedule. Protect Afatinib 30mg Tablet from heat and light.
Before starting treatment with the Giotrif tablet, do not forget to discuss your previous medical history with your doctor.
Contraception
Use effective methods of contraception to prevent pregnancy while taking Afatinib 30mg Tablet
Children and adolescents
Afatinib 30mg Tablet is not advisable for use in children and adolescents.
Pregnancy
Afatinib 30mg Tablet shouldn’t be used by women who are pregnant. It is recommended that this medication should be avoided during pregnancy.
Breastfeeding
Afatinib 30mg Tablet is not recommended for use in breastfeeding women unless it is necessary. Please consult your doctor.
Afatinib 30mg Tablet should be used with caution because it may increase the risk of skin reactions.
Avoid sunlight and use sunscreen during treatment with this medicine.
This medication may increase the risk of severe diarrhea and renal impairment.
This medication increases the risk of lung disorders like shortness of breath etc.
Close monitoring of liver function is required during the treatment with this medicine.
Afatinib 30mg Tablet may cause eye problems such as - pain in the eyes, blurred vision, and tearing.
Do not take 2 doses at the same time.
Do not crush, chew, or break the medicine.
May harm liver
Not safe for pregnant women
Do not drive if you experience dizziness.
May cause rash or skin irritation
Ans. Afatinib 30mg Tablet is used to treat non-small cell lung cancer that is also spread in other areas of the body and has abnormal EGF receptor genes which promote the growth of cancer cells.
Ans. Afatinib belongs to a class of medicines called tyrosine kinase inhibitors. This medicine blocks the signals of a particular protein which tells the cancer cells to grow.
Ans. Take Afatinib 30mg Tablet orally once a day and it should be taken at least 1 hour before or 3 hours after the meals. Do not stop the dosage before taking permission from your doctor.
Ans. Some common side effects of Afatinib 30mg Tablet are:- diarrhea, muscle pain, loss of appetite, skin rash, vomiting, stomach pain, blurred vision, change of taste, mouth sore, etc.
Ans. Do not take this medicine if you are allergic to afatinib, or other drugs that are used in this medicine.
Ans. It is available in the strength of 20mg, 30mg, 40mg.
Ans. In case you miss a dose try to take the medicine as soon as you remember or skip the dose and take your next dose according to your dosing schedule.
Ans. Do not drive if you experience any symptoms of dizziness because it may affect your ability to drive.
Ans. Afatinib 30mg Tablet is not recommended for pregnant women.
Ans. This medicine is not recommended for use in breastfeeding women unless it is necessary.
Ans. Interaction with alcohol is unknown. Please consult your doctor before consuming alcohol.
Ans. The effect of this medicine can be observed within 2 to 5 hours after oral administration.
Ans. Afatinib 30mg Tablet may harm your liver. Your doctor will monitor your liver functioning during the treatment with this medicine.
Ans. Store Afatinib 30mg Tablet at room temperature. Protect from heat and light.
Interactions may change how your medication works and increase the risk of side effects. Discuss with your doctor about your previous medical history.
Cyclosporine
Ritonavir
Ketoconazole
Lomitapide
Efavirenz
Mipomersen
Leflunomide
Afatinib 30mg Tablet should be used with caution in patients who are suffering from lung disease. This medicine can worsen your condition. Please refer to your doctor in case of this.
Afatinib 30mg Tablet may interact if you have kidney, liver, or heart disease. Your doctor will monitor you closely during the treatment with this drug.
Interaction with alcohol is unknown. Please consult your doctor before consuming alcohol.
Afatinib 30mg Tablet is not recommended for use in patients with known allergies to Afatinib.
Afatinib 30mg Tablet is contracted in patients with known hypersensitivity to Afatinib.
Reference
Afatinib: Drug Uses, mechanism, and Side Effects available at: https://reference.medscape.com/drug/gilotrif-afatinib-999864, https://go.drugbank.com/drugs/DB08916, and https://www.webmd.com/drugs/2/drug-164730/afatinib-oral/details.
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