Hepcinat 400mg Tablet
Rx RequiredSalt Composition: Sofosbuvir 400mg
Expiry Date: 01/2028
Buy at $70.55
Inclusive of all taxes
28 tablet
About The Product
Hepatitis C
Hepcinat 400mg tablet is an antiviral medication, used along with other medications, in the treatment of chronic Hepatitis C Virus (HCV) infection in adults. This medicine works to lower the growth and multiplication of viruses in the body and helps to eliminate the virus from the body.
Description
Sofosbuvir tends to inhibit the Hepatitis C NS5B protein. It shows a high barrier to the development of resistance.
Sofosbuvir is a prodrug of the Protide type, wherein the active phosphorylated nucleotide is granted with cell permeability and oral bioavailability. By hydrolysis of the carboxylate ester by either of the enzymes cathepsin A or carboxylesterase 1, Sofosbuvir is activated in the liver to the triphosphate GS-461203, which is followed by cleaving of the phosphoramidate by the enzyme histidine triad nucleotide-binding protein 1 (HINT1), with repeated phosphorylation.
Dephosphorylation tends to create the inactive metabolite GS-331077. The half-life of Sofosbuvir is 0.4 hours, and the half-life of GS-331077 is 27 hours.
Following a single 400 mg oral dose of Sofosbuvir, 80% is normally excreted in urine, 2.5% in expired air recovery, and 14% in feces.
Side Effects
Most side effects of Hepcinat 400mg tabletdo not require medical attention as they may disappear as your body adjusts to the medicine. In case these side effects become worse, consult your doctor immediately.
Headache
Fever
Chills
Nausea
Insomnia (difficulty in sleeping)
Tiredness
Loss of appetite
Fatigue
Anemia (low number of red blood cells)
Skin rash
Itching
Irritability
How To Use
- Take the Hepcinat tablet exactly as your healthcare provider tells you.
- Do not alter the dose strength on your own.
- Do not crush, chew, or break the tablet.
- Seek immediate medical attention, in case of overdose.
Safety Advice
Missed Doses
- If you miss a dose, take it as soon as you remember.
- If it is already time for your next scheduled dose, do not take the missed dose.
- Do not try to double the dose to catch up.
FAQs
Hepcinat (Sofosbuvir) 400mg tablet is an antiviral medication, used along with other medications, in the treatment of chronic Hepatitis C Virus (HCV) infection in adults.
Medical Disclaimer
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The content on this website has been produced solely for informational purposes. This is not intended to take the place of medical advice and care provided by a licensed professional, though.
This information may not include all potential side effects, warnings, and details about specific lab tests, medications, and medical conditions. Please ask your doctor any questions you may have about any drug or disease.
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