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Natco Pharma
28 tablet
Sofosbuvir 400mg
Keep in cold place
Delivering To: —
Overview
Hepcinat 400mg tablet is an antiviral medication, used along with other medications, in the treatment of chronic Hepatitis C Virus (HCV) infection in adults. This medicine works to lower the growth and multiplication of viruses in the body and helps to eliminate the virus from the body.
Hepatitis C
Sofosbuvir tends to inhibit the Hepatitis C NS5B protein. It shows a high barrier to the development of resistance. Sofosbuvir is a prodrug of the Protide type, wherein the active phosphorylated nucleotide is granted with cell permeability and oral bioavailability. By hydrolysis of the carboxylate ester by either of the enzymes cathepsin A or carboxylesterase 1, Sofosbuvir is activated in the liver to the triphosphate GS-461203, which is followed by cleaving of the phosphoramidate by the enzyme histidine triad nucleotide-binding protein 1 (HINT1), with repeated phosphorylation. Dephosphorylation tends to create the inactive metabolite GS-331077. The half-life of Sofosbuvir is 0.4 hours, and the half-life of GS-331077 is 27 hours. Following a single 400 mg oral dose of Sofosbuvir, 80% is normally excreted in urine, 2.5% in expired air recovery, and 14% in feces.
Most side effects of Hepcinat 400mg tabletdo not require medical attention as they may disappear as your body adjusts to the medicine. In case these side effects become worse, consult your doctor immediately.
Headache
Fever
Chills
Nausea
Insomnia (difficulty in sleeping)
Tiredness
Loss of appetite
Fatigue
Anemia (low number of red blood cells)
Skin rash
Itching
Irritability
Take the Hepcinat tablet exactly as your healthcare provider tells you. Do not alter the dose strength on your own. Do not crush, chew, or break the tablet.
Seek immediate medical attention, in case of overdose.
Alcohol
unsafe
It is advisable not to consume alcohol while taking this medicine.
Pregnancy
consult your doctor
Do not take Doxilyd 10mg injection without consulting the doctor, in case of pregnancy.
Breast Feeding
consult your doctor
Without a doctor's consultation, do not take this medicine if you're breastfeeding.
Driving
danger
It is advisable not to drive or operate heavy machinery, you may feel dizzy as one of the side effects of the medicine.
Kidney
caution
Do not take Doxilyd 10mg injection without a doctor's consultation in case of kidney problems.
Liver
caution
Share your medical history with the doctor in case of liver disease before taking this medicine.
If you miss a dose, take it as soon as you remember. If it is already time for your next scheduled dose, do not take the missed dose. Do not try to double the dose to catch up.
Hepcinat (Sofosbuvir) 400mg tablet is an antiviral medication, used along with other medications, in the treatment of chronic Hepatitis C Virus (HCV) infection in adults.
Take the Hepcinat tablet exactly as your healthcare provider tells you. Do not alter the dose strength on your own. Do not crush, chew, or break the tablet.
Side effects of Hepcinat are fever, nausea, anemia, insomnia, chills, muscle pain, cramps, fainting, and skin rash. If you experience these or any other side effect(s), make sure to consult your healthcare provider for the same.
Avoid the consumption of fatty or sugary foods and alcohol.
Do not drive or operate heavy machines if you feel unwell after taking this medicine.
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Natco Pharma
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