KISQALI

Mfd. by :- Novartis (Fulfilled By : Magicine Pharma)

Kisqali

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Magicine Pharma is registered with the Government Of NCT, India, Ministry Of Health in Government of Delhi, India, registration number DL-RAJ-122372 and as a wholesale distributor, department file No. 44208.

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Brand Name: Kisqali  

Generic Name: Ribociclib 

Manufacturer: Novartis  

Dosage Form: Tablet 

Strength: 600mg  

Composition: Ribociclib 

Packaging: 21 tablets (21 / strip) 

Indication: Breast cancer  

Storage: Store at room temperature  

Overview  

Kisqali (Ribociclib) tablet is used in the treatment of Breast cancer. It belongs to a group of cancer-fighting medications known as antineoplastics. Kisqali tablets work by blocking the action of the kinase protein which is important for the growth and division of cells. This tablet is used when the cancer cells have spread to other parts of the body. Take this medication as prescribed by your healthcare provider. Close monitoring of blood cell count is required during treatment with this medicine. The recommended dose of Kisqali tablets is decided by a doctor according to your previous medical condition and response to the treatment.  

Pharmacodynamics 

Ribociclib is an inhibitor of cyclin-dependent kinase (CDK) 4 and 6. These kinases are activated upon binding to D-cyclins and play a crucial role in signaling pathways which lead to cell cycle progression and cellular proliferation.  

Usage 

Kisqali tablet is an anti-cancer medication that is used in the treatment of metastatic breast cancer. This medicine helps to stop the growth of cancer cells. Take this medicine with or without food orally once a day. Swallow the whole tablet with a glass of water. Do not take this medicine in the wrong way as it may lead to some severe side effects. It is advisable not to change your regular dosing schedule without taking suggestions from your doctor. If you experience any signs and symptoms while receiving this medicine, inform your doctor immediately. Avoid driving because this medicine may cause excessive dizziness.  

Interactions  

Kisqali tablets can interact with other medications and it may increase the risk for side effects. Don’t forget to disclose and discuss your previous medical history with the doctor.  

Medicine Interactions 

  • Dofetilide  

  • Halothane  

  • Levofloxacin  

  • Abiraterone  

  • Clarithromycin  

  • Alfuzosin  

Disease Interaction 

  • Lung toxicity 

Alcohol Interaction  

  • Interaction with alcohol is unknown. Please consult your doctor before consuming alcohol.  

Contraindications  

  • Do not take this medicine if you are allergic to Ribociclib. 

  • Kisqali (Ribociclib) medicine is not recommended in patients known to be hypersensitive. 

This medicine may cause some common side effects. Discuss the risks and benefits of the Kisqali tablets with the doctor before starting the treatment. 

Common side effects  

  • Headache  

  • Decreased white blood cell count  

  • Back pain  

  • Tingling of hands and feet 

  • Shortness of breath  

  • Swollen glands  

  • Coughing up blood 

  • Unusual weakness 

  • Nosebleeds  

  • Bruising  

  • Allergic reactions  

  • Irregular heartbeat  

  • Decreased appetite  

  • Weight gain  

  • Fainting  

  • Bloating  

  • Chills  

  • Fever  

  • Pale skin  

  • Sore throat  

  • Bleeding  

  • Itching  

  • Loss of strength  

  • Changed sense of taste  

  • Trouble sleeping  

  • Seizures  

  • Vomiting  

  • Diarrhea  

  • Chest tightness  

  • Stomach pain  

  • Nausea 

  • Unusual tiredness  

Note - Immediately contact your doctor or healthcare provider if any side effects occur  

Take this medicine as prescribed by your doctor. Do not stop or skip your regular dosing schedule.  

Missed dose  

  • It is advisable not to miss a dose. If you miss a scheduled dose of Kisqali tablet, contact your doctor immediately.  

Overdose  

  • In case of an overdose of Kisqali tablets, the doctor will provide emergency medical treatment.  

 

Warnings 

Before starting treatment with Kisqali medicine, please inform your doctor about your previous medical history. If you experience any signs and symptoms while receiving this medication, do not ignore those symptoms because it may lead to higher risk.  

  •  Contraception  

  • Use suitable methods of contraception to prevent pregnancy while taking Kisqali tablets.  

  • Children and adolescents  

  •   Kisqali tablets are not advisable for use in children. Under the age of 18. 

Warnings for female  

  • Pregnancy 

  • Do not use  Kisqali (Ribociclib) if you are planning to become pregnant. Avoid this medication at the time of pregnancy.  

  • Breastfeeding 

  • This medicine is not recommended in breastfeeding unless it is required. Please consult with your doctor before starting treatment with  Kisqali medicine. 

Precautions 

  • Kisqali tablets should be used with caution in patients who have prolongation of QT interval.  

  • Close monitoring of liver function is required during treatment with this medicine.  

  • Do not forget to disclose and discuss your previous history with your healthcare provider. 

  • Kisqali medicine may decrease white blood cells in some patients.   

  • Do not skip your regular dosing schedule.  

  • Inform your doctor if you experience any side effects like - dizziness, nausea, abdominal pain, loss of appetite, and vomiting. 

Cautions 

  • Do not drive or operate heavy machinery. 

  • Do not crush or break the tablet.  

  • Not safe for pregnant women.  

  • Do not breastfeed while receiving this medication. 

Q1. What is Kisqali (Ribociclib)? 

Ans. It is used in the treatment of Breast cancer. It belongs to a group of cancer-fighting medications known as antineoplastics. 

 

Q2. How does Kisqali work? 

Ans. This medicine works by blocking the action of the kinase protein which is important for the growth and division of cells. 

 

Q3. What are the side effects?  

Ans. Some common side effects are:- fast heartbeat, bleeding, seizures, diarrhea, back pain, constipation, etc.  

 

Q4.  How to take this medicine?  

Ans. It is important to take this medicine as prescribed by your doctor.  

 

Q5. What should I avoid while receiving this medication?  

Ans. Follow your doctor’s advice about any restrictions on food and other activities. 

 

Q6. What happens if I miss a dose?  

Ans. If you miss a scheduled dose of Kisqali tablet, contact your doctor immediately. 

 

Q7.  Can I drive after taking this medicine?  

Ans. This medicine may affect your vision and your ability to concentrate. 

 

Q8.  In what strength is it available?  

Ans. It is available in the strength of 600mg.  

 

Q9. Can I take this medicine during pregnancy?  

Ans. This medicine is not recommended during pregnancy. 

 

Q10. Does this medicine affect liver function?  

Ans. Please consult your doctor before consuming this drug. 

 

Q11. Can I consume alcohol while receiving this medicine?  

Ans. Please consult your doctor before consuming alcohol. 

 

Q12. Can I take this medicine during breastfeeding?  

Ans. This medicine is not recommended in breastfeeding unless it is necessary. 

 

Q13.  What are the storage conditions?  

Ans. Store this medicine at room temperature. 

Above Content has been reviewed by Professionals