Marketed By
novartis india ltd
Pack of
21 Tablets in Strip
Salt Composition
Ribociclib
Storage
Keep in cold place
Delivering To: —
All Substitutes
Overview
Kisqali 600mg Tablet contain active ingredient Ribociclib. It is a targeted therapy anticancer drug prescribed to treat metastatic breast cancer. It works by blocking the action of specific proteins to slow down the growth of cancer cells and progression of disease. It can be used alone or in combination with other medicines. It should be taken in dose and duration as advice by the doctor. Don't take more than the recommended dose.
Indication
Breast Cancer
Uses
- Metastatic breast cancer
Side Effects
Kisqali 600mg Tablet can cause multiple side effects, most of which are mild to moderate and often temporary. Patients are advised to inform their healthcare provider immediately if symptoms stays for prolonged period of time.
Common side effects include:
- Infection
- Anemia
- Decreased appetite
- Vomiting
- Headache
- Low blood platelets
- Decreased potassium level in blood
- Decreased white blood cell count
- Dizziness
- Vertigo
- Fainting
- Increased lacrimation
- Breathlessness
- Cough
- Itching
- Abnormal liver enzyme
- Rash
- Nausea
- Constipation
- Fatigue
- Diarrhea
- Decreased white blood cell count
- Hair loss
How To Use
- Take Kisqali 600mg Tablet in exact dose as prescribed by the doctor. The typical dose of this capsule varies with age and overall health factor of the patient. It can be taken with or without food but at a fixed time each day to get better results.
- It should be swallowed as a whole with water without crushing, chewing, or opening the capsule. Don't miss a dose or overdose the medicine.
How It Works
Kisqali 600mg Tablet contain active ingredient Ribociclib. It is a targeted therapy anticancer drug that works by blocking the action of proteins (kinases) which are responsible for the growth and division of cells. Results in slows the growth of cancer cells and eventually kills them.
Safety Advice
Alcohol
UNSAFE
Pregnancy
CONSULT YOUR DOCTOR
Breast Feeding
CONSULT YOUR DOCTOR
Driving
DANGER
Kidney
PRECAUTION
Liver
PRECAUTION
FAQs
It is used in the treatment of metastatic breast cancer. It belongs to a group of cancer-fighting medications known as antineoplastics.
This medicine works by blocking the action of the kinase protein which is important for the growth and division of cells.
It is important to take Kisqali 600mg Tablet as prescribed by your doctor.
Kisqali 600mg Tablet may decrease your ability to drive, affect your vision, or make you feel sleepy. Do not drive if any symptoms occur.
This medicine is not recommended in breastfeeding unless it is necessary as it may harm the unborn baby.
References
- Slamon, D. J., Neven, P., Chia, S., Fasching, P. A., De Laurentiis, M., Im, S. A., ... & Jerusalem, G. (2020). Overall survival with ribociclib plus fulvestrant in advanced breast cancer. New England Journal of medicine, 382(6), 514-524. https://pubmed.ncbi.nlm.nih.gov/31826360/
- Slamon, D., Lipatov, O., Nowecki, Z., McAndrew, N., Kukielka-Budny, B., Stroyakovskiy, D., ... & Hortobagyi, G. (2024). Ribociclib plus endocrine therapy in early breast cancer. New England Journal of Medicine, 390(12), 1080-1091. https://pubmed.ncbi.nlm.nih.gov/38507751/
- Im, S. A., Lu, Y. S., Bardia, A., Harbeck, N., Colleoni, M., Franke, F., ... & Tripathy, D. (2019). Overall survival with ribociclib plus endocrine therapy in breast cancer. New England journal of medicine, 381(4), 307-316. https://www.nejm.org/doi/full/10.1056/NEJMoa1903765
- Tripathy, D., Bardia, A., & Sellers, W. R. (2017). Ribociclib (LEE011): mechanism of action and clinical impact of this selective cyclin-dependent kinase 4/6 inhibitor in various solid tumors. Clinical Cancer Research, 23(13), 3251-3262. https://pubmed.ncbi.nlm.nih.gov/28351928/
- Hortobagyi, G. N., Stemmer, S. M., Burris, H. A., Yap, Y. S., Sonke, G. S., Paluch-Shimon, S., ... & O’Shaughnessy, J. (2016). Ribociclib as first-line therapy for HR-positive, advanced breast cancer. New England journal of medicine, 375(18), 1738-1748. https://www.nejm.org/doi/full/10.1056/NEJMoa1609709
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