Kryxana 200mg Tablet

Kryxana 200mg Tablet

Prescription requiredRx Required

Salt Composition: Ribociclib

Expiry Date: 01/2028

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Buy at $352.94

$352.94

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21 Tablet

About The Product

  • Metastatic Breast Cancer
  • Kryxana 200mg Tablet is an anticancer medicine with the active ingredient Ribociclib (200mg). It is prescribed to treat metastatic breast cancer. It belongs to a group of cancer-fighting medications known as antineoplastics.
  • This tablet works by blocking the action of the kinase protein, which is important for the growth and division of cells. It should be taken at the same time each day to get effective results. Don't take more than the recommended dose.
  • Typically, Kryxana should be administered as monotherapy combined with endocrine therapy once per day, with the tablet swallowed intact with or without food intake.
  • Patients using Kryxana are recommended not to consume grapefruit or pomegranate juices.
  • Liver function tests and complete blood count should be done routinely.

Uses

Treatment of HR-positive, HER2-negative advanced or metastatic breast cancer in adults

Side Effects

Most side effects of Kryxana 200mg Tablet do not require medical attention as they may disappear as your body adjusts to the medicine. In case these side effects become worse, consult your doctor immediately. Following are the side effects:

  • Fatigue and tiredness
  • Headache and dizziness (including vertigo or fainting)
  • Nausea, vomiting, diarrhea, or constipation
  • Abdominal pain
  • Rash, itching, or skin changes
  • Hair thinning or loss
  • Cough, breathlessness, or nasal inflammation
  • Fever and night sweats
  • Trouble sleeping (insomnia)
  • Back or joint pain, muscle cramps
  • Swelling in the face, legs, ankles, or feet (edema) with weight gain
  • Increased tearing (watery eyes) or dry eyes
  • Reduced appetite
  • Changes in blood counts (low red cells, white cells, or platelets)
  • Infections
  • Elevated liver enzymes or creatinine levels
  • Low calcium, potassium, or blood sugar (especially with insulin or sulphonylureas)
  • Severe neutropenia (very low white blood cell counts)
  • Hepatobiliary toxicity (serious liver problems or liver failure)
  • Heart failure or prolonged QT interval (abnormal heart rhythm)
  • Gastrointestinal disorders
  • Hypothyroidism
  • Pneumonitis or interstitial lung disease
  • Generalized swelling in the body

How To Use

  • Take Kryxana 200mg Tablet in exact dose as prescribed by the doctor.
  • The typical dose of this tablet varies with age, type & stage of the cancer, and overall health factor of the patient.
  • It can be taken with or without food but at a fixed time each day to get better results.
  • Ribociclib Tablet should be swallowed as a whole with water without crushing, chewing, or opening the capsule.
  • Don't miss a dose or overdose the medicine.

How It Works

  • Kryxana 200mg Tablet is an anticancer medicine with active ingredient Ribociclib (200mg). It belongs to a group of cancer-fighting medications known as antineoplastics.
  • This tablet works by blocking the action of the kinase protein, which is important for the growth and division of cells. As a result, it slows the progression of cancer.


Safety Advice

Alcohol
It is advisable not to consume alcohol while taking medicine, as it may increase dizziness.
Pregnancy
Do not take Kryxana 200mg Tablet may be considered unsafe during pregnancy as they may cause harm to the developing fetus.
Breast Feeding
Kryxana 200mg Tablet is probably not safe if you're breastfeeding, as it may pass through breast milk and cause toxicity to the newborn.
Driving
It is advisable not to drive or operate heavy machinery, you may feel dizzy as one of the side effects of the medicine.
Kidney
Do not consume Kryxana 200mg Tablet without a doctor's consultation in case of kidney problems.
Liver
Share your medical history with the doctor in case of liver disease before taking this medicine.

Missed Doses

  • ​If you forget to take a dose of Kryxana Tablet, consult your doctor.
  • Don’t double up the next dose to cope with the missed one unless your doctor recommends it.​​

Quick Tips

  • If a dosage is skipped or vomiting occurs after administration of the tablet, just skip the missed dose and keep on with the next scheduled one; however, never take a double dose.
  • The tablet is supposed to be taken once a day, either with or without meals, but at the same time every day in order to prevent missing a dose.
  • It is important to use effective birth control measures to avoid getting pregnant while on this treatment.
  • Make sure to notify your physician about your condition in case you are pregnant, want to become pregnant, or are nursing a child.
  • As the tablet may cause dizziness, do not drive or perform tasks that require clear thinking until its effects are determined.
  • Blood testings can be done on a frequent basis in order to check the state of your liver and blood count.

FAQs

It is an anti-cancer medication that is used in the treatment of breast cancer.

This medicine helps to stop the growth of cancer cells in breast.

References

  • Abdelmalak, M., Singh, R., Anwer, M., et al. (2022). The renaissance of CDK inhibitors in breast cancer therapy: An update on clinical trials and therapy resistance. Cancers, 14(21), 5388 - https://pubmed.ncbi.nlm.nih.gov/36358806/
  • Dajsakdipon, T., Susiriwatananont, T., Wongkraisri, C., Ithimakin, S., Parinyanitikul, N., Supavavej, A., & TSCO Breast Oncology Group. (2024). Comparative effectiveness analysis of survival with first-line palbociclib or ribociclib plus aromatase inhibitor in HR+/HER2− advanced breast cancer: Preliminary real‑world data from Thailand. BMC Cancer, 24(1), 1018 - https://link.springer.com/article/10.1186/s12885-024-12765-x
  • Hortobagyi, G. N., Stemmer, S. M., Burris, H. A., Yap, Y. S., Sonke, G. S., Paluch-Shimon, S., … Goetz, M. P. (2022). Overall survival with ribociclib plus letrozole in advanced breast cancer. New England Journal of Medicine, 386(18), 942–950 - https://pubmed.ncbi.nlm.nih.gov/35263519/
  • Ji, Y., Yartsev, V., Quinlan, M., Serra, P., Wang, Y., Chakraborty, A., & Miller, M. (2023). Justifying ribociclib dose in patients with advanced breast cancer with renal impairment based on PK, safety, and efficacy data: An innovative approach integrating data from a dedicated renal impairment study and oncology clinical trials. Clinical Pharmacokinetics, 62(3), 493–504 - https://pubmed.ncbi.nlm.nih.gov/36800111/
  • Xu, J., Wang, R., & Shen, K. (2025). A post-marketing disproportionality analysis of the safety of ribociclib based on the FDA Adverse Event Reporting System. Therapeutic Advances in Drug Safety, 16, 20420986251324633 - https://pmc.ncbi.nlm.nih.gov/articles/PMC11869255/

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